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Gordon Florence
Gordon Florence
School of Chemistry & BSRC, University of St Andrews
Verified email at st-andrews.ac.uk
Title
Cited by
Cited by
Year
A practical synthesis of (+)-discodermolide and analogues: fragment union by complex aldol reactions
I Paterson, J Gordon, K Gerlach, JP Scott, N Sereinig
Journal of the American Chemical Society 123 (39), 9535-9544, 2001
2892001
Total Synthesis of the Antimicrotubule Agent (+)‐Discodermolide Using Boron‐Mediated Aldol Reactions of Chiral Ketones
I Paterson, GJ Florence, K Gerlach, JP Scott
Angewandte Chemie 112 (2), 385-388, 2000
2142000
Highly chemoselective oxidation of 1, 5-diols to δ-lactones with TEMPO/BAIB
TM Hansen, GJ Florence, P Lugo-Mas, J Chen, JN Abrams, CJ Forsyth
Tetrahedron letters 44 (1), 57-59, 2003
2132003
Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 5:  Linkage of Fragments C1-6 and C7-24 and Finale
SJ Mickel, D Niederer, R Daeffler, A Osmani, E Kuesters, E Schmid, ...
Organic process research & development 8 (1), 122-130, 2004
1942004
Large-Scale Synthesis of the Anti-Cancer Marine Natural Product (+)-Discodermolide. Part 4:  Preparation of Fragment C7-24
SJ Mickel, GH Sedelmeier, D Niederer, F Schuerch, M Seger, K Schreiner, ...
Organic process research & development 8 (1), 113-121, 2004
1292004
Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin
GJ Florence, NM Gardner, I Paterson
Natural product reports 25 (2), 342-375, 2008
1232008
1, 6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide
I Paterson, O Delgado, J Gordon, I Lyothier, JP Scott, N Sereinig
Organic Letters 5 (1), 35-38, 2003
1172003
Approaches to CNS drug delivery with a focus on transporter-mediated transcytosis
R Abdul Razzak, GJ Florence, FJ Gunn-Moore
International journal of molecular sciences 20 (12), 3108, 2019
862019
Synthesis of (+)-discodermolide and analogues by control of asymmetric induction in aldol reactions of γ-chiral (Z)-enals
I Paterson, GJ Florence
Tetrahedron Letters 41 (35), 6935-6939, 2000
792000
Stereocontrolled Total Synthesis of (−)‐Aurisides A and B
I Paterson, GJ Florence, AC Heimann, AC Mackay
Angewandte Chemie International Edition 44 (7), 1130-1133, 2005
742005
The development of a practical total synthesis of discodermolide, a promising microtubule‐stabilizing anticancer agent
I Paterson, GJ Florence
European Journal of Organic Chemistry 2003 (12), 2193-2208, 2003
742003
Total synthesis and stereochemical reassignment of (+)-dolastatin 19
I Paterson, AD Findlay, GJ Florence
Organic Letters 8 (10), 2131-2134, 2006
612006
An internal thioester in a pathogen surface protein mediates covalent host binding
M Walden, JM Edwards, AM Dziewulska, R Bergmann, G Saalbach, ...
Elife 4, e06638, 2015
582015
Discodermolide interferes with the binding of tau protein to microtubules
S Kar, GJ Florence, I Paterson, LA Amos
FEBS letters 539 (1-3), 34-36, 2003
582003
Total Synthesis of (−)‐Reidispongiolide A, an Actin‐Targeting Marine Macrolide
I Paterson, K Ashton, R Britton, G Cecere, G Chouraqui, GJ Florence, ...
Angewandte Chemie International Edition 46 (32), 6167-6171, 2007
522007
Total Synthesis of (−)‐Reidispongiolide A, an Actin‐Targeting Macrolide Isolated from the Marine Sponge Reidispongia coerulea
I Paterson, K Ashton, R Britton, G Cecere, G Chouraqui, GJ Florence, ...
Chemistry–An Asian Journal 3 (2), 367-387, 2008
442008
The trypanosome alternative oxidase: a potential drug target?
SK Menzies, LB Tulloch, GJ Florence, TK Smith
Parasitology 145 (2), 175-183, 2018
422018
Direct and indirect approaches to identify drug modes of action
LB Tulloch, SK Menzies, RP Coron, MD Roberts, GJ Florence, TK Smith
Iubmb Life 70 (1), 9-22, 2018
382018
Total synthesis and stereochemical reassignment of (+)-dolastatin 19, a cytotoxic marine macrolide isolated from Dolabella auricularia
I Paterson, AD Findlay, GJ Florence
Tetrahedron 63 (26), 5806-5819, 2007
382007
A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel
DA Dabydeen, GJ Florence, I Paterson, E Hamel
Cancer chemotherapy and pharmacology 53, 397-403, 2004
312004
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