Suivre
Tasha N. Sims
Tasha N. Sims
AbbVie, Regeneron, NYU, University of Alberta, Washington University
Adresse e-mail validée de abbvie.com
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The immunological synapse
SK Bromley, WR Burack, KG Johnson, K Somersalo, TN Sims, C Sumen, ...
Annual review of immunology 19 (1), 375-396, 2001
12332001
The immunological synapse balances T cell receptor signaling and degradation
KH Lee, AR Dinner, C Tu, G Campi, S Raychaudhuri, R Varma, TN Sims, ...
science 302 (5648), 1218-1222, 2003
6642003
Opposing effects of PKCθ and WASp on symmetry breaking and relocation of the immunological synapse
TN Sims, TJ Soos, HS Xenias, B Dubin-Thaler, JM Hofman, JC Waite, ...
Cell 129 (4), 773-785, 2007
4072007
CX3CR1+ interstitial dendritic cells form a contiguous network throughout the entire kidney
TJ Soos, TN Sims, L Barisoni, K Lin, DR Littman, ML Dustin, PJ Nelson
Kidney international 70 (3), 591-596, 2006
3492006
The immunological synapse: integrins take the stage
TN Sims, ML Dustin
Immunological reviews 186 (1), 100-117, 2002
2132002
WIP deficiency reveals a differential role for WIP and the actin cytoskeleton in T and B cell activation
IM Antón, MA de la Fuente, TN Sims, S Freeman, N Ramesh, JH Hartwig, ...
Immunity 16 (2), 193-204, 2002
2122002
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes
N Anikeeva, K Somersalo, TN Sims, VK Thomas, ML Dustin, Y Sykulev
Proceedings of the National Academy of Sciences 102 (18), 6437-6442, 2005
2092005
Tumor-reprogrammed resident T cells resist radiation to control tumors
A Arina, M Beckett, C Fernandez, W Zheng, S Pitroda, SJ Chmura, ...
Nature communications 10 (1), 3959, 2019
1832019
Lateral membrane waves constitute a universal dynamic pattern of motile cells
HG Döbereiner, BJ Dubin-Thaler, JM Hofman, HS Xenias, TN Sims, ...
Physical review letters 97 (3), 038102, 2006
1802006
Cytotoxic T lymphocytes form an antigen-independent ring junction
K Somersalo, N Anikeeva, TN Sims, VK Thomas, RK Strong, T Spies, ...
The Journal of clinical investigation 113 (1), 49-57, 2004
1492004
Disturbed MHC regulation in the IFN-gamma knockout mouse. Evidence for three states of MHC expression with distinct roles for IFN-gamma.
N Goes, T Sims, J Urmson, D Vincent, V Ramassar, PF Halloran
Journal of immunology (Baltimore, Md.: 1950) 155 (10), 4559-4566, 1995
801995
Central role for interferon-γ receptor in the regulation of renal MHC expression
Y Takei, TN Sims, J Urmson, PF Halloran
Journal of the American Society of Nephrology 11 (2), 250-261, 2000
352000
First-in-human study of REGN3767 (R3767), a human LAG-3 monoclonal antibody (mAb),±cemiplimab in patients (pts) with advanced malignancies.
KP Papadopoulos, NJ Lakhani, ML Johnson, H Park, D Wang, TA Yap, ...
Journal of Clinical Oncology 37 (15_suppl), 2508-2508, 2019
322019
Clinical activity of fianlimab (REGN3767), a human anti-LAG-3 monoclonal antibody, combined with cemiplimab (anti-PD-1) in patients (pts) with advanced melanoma.
O Hamid, D Wang, TM Kim, SW Kim, NJ Lakhani, ML Johnson, ...
Journal of Clinical Oncology 39 (15_suppl), 9515-9515, 2021
272021
SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery
S Hu-Lieskovan, S Bhaumik, K Dhodapkar, JCJB Grivel, S Gupta, ...
Journal for Immunotherapy of Cancer 8 (2), 2020
272020
In Vivo Class Ii Transactivator Expression In Mice Is Induced By A Non-interferon-γ Mechanism In Response To Local Injury1, 2
TN Sims, NB Goes, V Ramassar, J Urmson, PF Halloran
Transplantation 64 (12), 1657-1664, 1997
261997
Mouse class II transactivator: cDNA sequence and amino acid comparison with the human class II transactivator
TN Sims, JF Elliott, V Ramassar, DW Denney Jr, PF Halloran
Immunogenetics 45, 220-222, 1997
221997
MHC expression in organ transplants: lessons from the knock-out mice
PF Halloran, N Goes, J Urmson, V Ramassar, M Hobart, T Sims, SL Lui, ...
Transplantation proceedings 29 (1-2), 1041-1044, 1997
171997
The role of the class II transactivator (CIITA) in MHC class I and II regulation and graft rejection in kidney
TN Sims, M Afrouzian, J Urmson, LF Zhu, PF Halloran
American Journal of Transplantation 1 (3), 211-221, 2001
162001
Potential predictive and prognostic biomarkers identified in baseline plasma samples from the VELOUR trial.
TN Sims, B Gao, M Chiron, P Mancini, E Dochy, I Lowy
Journal of Clinical Oncology 33 (15_suppl), e14536-e14536, 2015
152015
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