Suivre
Helena Ramos
Helena Ramos
REQUIMTE
Adresse e-mail validée de icbas.up.pt
Titre
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Année
p53 and glucose metabolism: an orchestra to be directed in cancer therapy
AS Gomes, H Ramos, J Soares, L Saraiva
Pharmacological research 131, 75-86, 2018
1162018
DIMP 53‐1: a novel small‐molecule dual inhibitor of p53–MDM 2/X interactions with multifunctional p53‐dependent anticancer properties
J Soares, M Espadinha, L Raimundo, H Ramos, AS Gomes, S Gomes, ...
Molecular Oncology 11 (6), 612-627, 2017
472017
New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma
S Gomes, L Raimundo, J Soares, JB Loureiro, M Leao, H Ramos, ...
Cancer letters 446, 90-102, 2019
442019
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule
J Soares, L Raimundo, NAL Pereira, Â Monteiro, S Gomes, C Bessa, ...
Oncotarget 7 (4), 4326, 2016
442016
Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53–MDM2 interaction
M Leão, J Soares, S Gomes, L Raimundo, H Ramos, C Bessa, G Queiroz, ...
Life sciences 142, 60-65, 2015
362015
A selective p53 activator and anticancer agent to improve colorectal cancer therapy
H Ramos, MIL Soares, J Silva, L Raimundo, J Calheiros, C Gomes, F Reis, ...
Cell Reports 35 (2), 2021
302021
SLMP53-1 inhibits tumor cell growth through regulation of glucose metabolism and angiogenesis in a P53-dependent manner
H Ramos, J Calheiros, J Almeida, V Barcherini, S Santos, ATP Carvalho, ...
International Journal of Molecular Sciences 21 (2), 596, 2020
242020
SLMP53-2 restores wild-type-like function to mutant p53 through Hsp70: promising activity in hepatocellular carcinoma
S Gomes, B Bosco, JB Loureiro, H Ramos, L Raimundo, J Soares, ...
Cancers 11 (8), 1151, 2019
242019
BRCA1/P53: Two strengths in cancer chemoprevention
L Raimundo, H Ramos, JB Loureiro, J Calheiros, L Saraiva
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1873 (1), 188339, 2020
212020
p53 family interactions and yeast: together in anticancer therapy
S Gomes, M Leao, L Raimundo, H Ramos, J Soares, L Saraiva
Drug Discovery Today 21 (4), 616-624, 2016
172016
SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations
AS Gomes, H Ramos, S Gomes, JB Loureiro, J Soares, V Barcherini, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1864 (1), 129440, 2020
162020
Naphthoylhydrazones: coordination to metal ions and biological screening
N Ribeiro, AM Galvão, CSB Gomes, H Ramos, R Pinheiro, L Saraiva, ...
New Journal of Chemistry 43 (45), 17801-17818, 2019
152019
A simple linearization method unveils hidden enzymatic assay interferences
MF Pinto, J Ripoll-Rozada, H Ramos, EE Watson, C Franck, RJ Payne, ...
Biophysical Chemistry 252, 106193, 2019
62019
Targeting neuroblastoma with a new inhibitor of the TAp73 interaction with MDM2 and mutant p53
L Raimundo, S Gomes, J Soares, J Loureiro, M Leão, H Ramos, ...
MDPI AG, 2019
2019
Strategies to Discover p53 Activators and a p73 Activator for Neuroblastoma
E Sousa, S Gomes, L Raimundo, J Soares, J Loureiro, M Leão, H Ramos, ...
Multidisciplinary Digital Publishing Institute Proceedings 22 (1), 56, 2019
2019
Flavones: Promising Basis for Drug Devel-opment of Caspase Activators
JP Moreira, H Ramos, S Salazar, MM Pinto, L Saraiva, H Cidade
2017
Uncovering the binding of the anticancer small molecule SLMP53-1 to mutant p53R280K
AS Gomes, S Gomes, J Soares, H Ramos, C Oliveira, F Freire, B Pinheiro, ...
2017
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