| Differential affinities of visual arrestin, βarrestin1, and βarrestin2 for G protein-coupled receptors delineate two major classes of receptors RH Oakley, SA Laporte, JA Holt, MG Caron, LS Barak Journal of Biological Chemistry 275 (22), 17201-17210, 2000 | 1060 | 2000 |
| β-Arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3 PH McDonald, CW Chow, WE Miller, SA Laporte, ME Field, FT Lin, ... Science 290 (5496), 1574-1577, 2000 | 1051 | 2000 |
| The β2-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis SA Laporte, RH Oakley, J Zhang, JA Holt, SSG Ferguson, MG Caron, ... Proceedings of the National Academy of Sciences 96 (7), 3712-3717, 1999 | 865 | 1999 |
| Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and ß-arrestin proteins A Claing, SA Laporte, MG Caron, RJ Lefkowitz Progress in neurobiology 66 (2), 61-79, 2002 | 739 | 2002 |
| Association of β-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization RH Oakley, SA Laporte, JA Holt, LS Barak, MG Caron Journal of Biological Chemistry 274 (45), 32248-32257, 1999 | 716 | 1999 |
| Role for G protein-coupled receptor kinase in agonist-specific regulation of μ-opioid receptor responsiveness J Zhang, SSG Ferguson, LS Barak, SR Bodduluri, SA Laporte, PY Law, ... Proceedings of the National Academy of Sciences 95 (12), 7157-7162, 1998 | 646 | 1998 |
| Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-β-arrestin complexes after receptor endocytosis RH Oakley, SA Laporte, JA Holt, LS Barak, MG Caron Journal of Biological Chemistry 276 (22), 19452-19460, 2001 | 562 | 2001 |
| The interaction of β-arrestin with the AP-2 adaptor is required for the clustering of β2-adrenergic receptor into clathrin-coated pits SA Laporte, RH Oakley, JA Holt, LS Barak, MG Caron Journal of Biological Chemistry 275 (30), 23120-23126, 2000 | 522 | 2000 |
| The stability of the G protein-coupled receptor-β-arrestin interaction determines the mechanism and functional consequence of ERK activation A Tohgo, EW Choy, D Gesty-Palmer, KL Pierce, S Laporte, RH Oakley, ... Journal of Biological Chemistry 278 (8), 6258-6267, 2003 | 436 | 2003 |
| The oxytocin receptor HH Zingg, SA Laporte Trends in Endocrinology & Metabolism 14 (5), 222-227, 2003 | 373 | 2003 |
| The experimental power of FR900359 to study Gq-regulated biological processes R Schrage, AL Schmitz, E Gaffal, S Annala, S Kehraus, D Wenzel, ... Nature communications 6 (1), 10156, 2015 | 342 | 2015 |
| Cellular trafficking of G protein-coupled receptor/β-arrestin endocytic complexes J Zhang, LS Barak, PH Anborgh, SA Laporte, MG Caron, SSG Ferguson Journal of Biological Chemistry 274 (16), 10999-11006, 1999 | 319 | 1999 |
| Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus LS Barak, RH Oakley, SA Laporte, MG Caron Proceedings of the National Academy of Sciences 98 (1), 93-98, 2001 | 292 | 2001 |
| Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET Y Namkung, C Le Gouill, V Lukashova, H Kobayashi, M Hogue, E Khoury, ... Nature communications 7 (1), 12178, 2016 | 272 | 2016 |
| Muscarinic supersensitivity and impaired receptor desensitization in G protein–coupled receptor kinase 5–deficient mice RR Gainetdinov, LM Bohn, JKL Walker, SA Laporte, AD Macrae, ... Neuron 24 (4), 1029-1036, 1999 | 254 | 1999 |
| Phosphoinositide 3-kinase regulates β2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/β-arrestin complex SV Naga Prasad, SA Laporte, D Chamberlain, MG Caron, L Barak, ... The Journal of cell biology 158 (3), 563-575, 2002 | 247 | 2002 |
| C5L2 is a functional receptor for acylation-stimulating protein D Kalant, R MacLaren, W Cui, R Samanta, PN Monk, SA Laporte, ... Journal of Biological Chemistry 280 (25), 23936-23944, 2005 | 243 | 2005 |
| The conformational signature of β-arrestin2 predicts its trafficking and signalling functions MH Lee, KM Appleton, EG Strungs, JY Kwon, TA Morinelli, YK Peterson, ... Nature 531 (7596), 665-668, 2016 | 224 | 2016 |
| β-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a β-arrestin binding site in β2-adaptin SA Laporte, WE Miller, KM Kim, MG Caron Journal of Biological Chemistry 277 (11), 9247-9254, 2002 | 205 | 2002 |
| Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9 LM Luttrell, J Wang, B Plouffe, JS Smith, L Yamani, S Kaur, ... Science Signaling 11 (549), eaat7650, 2018 | 192 | 2018 |
Marc G. CaronJames B. Duke Professor, Cell Biology, Medicine, Neurobiology Duke UniversityAdresse e-mail validée de duke.edu
