| Consequences of trace metal variability and supplementation on Chinese hamster ovary (CHO) cell culture performance: A review of key mechanisms and considerations RJ Graham, H Bhatia, S Yoon Biotechnology and Bioengineering 116 (12), 3446-3456, 2019 | 74 | 2019 |
| Zinc supplementation improves the harvest purity of β-glucuronidase from CHO cell culture by suppressing apoptosis RJ Graham, S Ketcham, A Mohammad, BMB Bandaranayake, T Cao, ... Applied microbiology and biotechnology 104, 1097-1108, 2020 | 17 | 2020 |
| Effect of iron addition on mAb productivity and oxidative stress in Chinese hamster ovary culture RJ Graham, A Mohammad, G Liang, Q Fu, B Kuang, A Polanco, YS Lee, ... Biotechnology Progress 37 (5), e3181, 2021 | 8 | 2021 |
| Zinc supplementation modulates intracellular metal uptake and oxidative stress defense mechanisms in CHO cell cultures RJ Graham, SA Ketcham, A Mohammad, E Paregol, S Yoon, G Zou, T Ju, ... Biochemical Engineering Journal 169, 107928, 2021 | 8 | 2021 |
| Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events EJ Fratz‐Berilla, P Angart, RJ Graham, DN Powers, A Mohammad, ... Biotechnology and Bioengineering 117 (9), 2802-2815, 2020 | 7 | 2020 |
| Trace metal optimization in CHO cell culture through statistical design of experiments A Polanco, G Liang, SY Park, Y Wang, RJ Graham, S Yoon Biotechnology Progress 39 (6), e3368, 2023 | 1 | 2023 |
| Achieving product quality targets while maintaining high titer in CHO cell culture processes R Graham, T DiRocco, S Varma, N Vijayasankaran, A Abdun-Nabi | | 2023 |
| Consequences of Trace Metal Variability and Supplementation on Cho Cell Culture Performance: Impacts on Productivity and Quality of Recombinant Therapeutic Proteins R Graham University of Massachusetts Lowell, 2021 | | 2021 |
| Trace metal variability in culture media can impair CHO culture performance by enhancing mechanisms of oxidative stress S Yoon, A Polanco, Y Lee, R Graham, G Liang, A Mohammad American Chemical Society SciMeetings 1 (2), 2020 | | 2020 |
| Integrated omics modeling of trace metal effects on lactate metabolism and product quality for improved bioprocess control A Polanco, R Graham, S Yoon American Chemical Society SciMeetings 1 (1), 2020 | | 2020 |
| Zinc enhances beta-glucuronidase secretion from CHO cells by suppressing apoptosis R Graham, S Ketcham, B Ghosh, A Mohammad, P Faustino, M Ashraf, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Automated and high throughput ICP-MS sample prep platform to study the effect of trace metals in upstream manufacturing of therapeutic proteins A Mohammad, R Graham, S Ketcham, C Madhavarao, C Agarabi, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
Seongkyu YoonUniversity of Massachusetts LowellAdresse e-mail validée de uml.edu
