Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila GR Jackson, M Wiedau-Pazos, TK Sang, N Wagle, CA Brown, ... Neuron 34 (4), 509-519, 2002 | 586 | 2002 |
Neuronal cell death mechanisms in major neurodegenerative diseases H Chi, HY Chang, TK Sang International journal of molecular sciences 19 (10), 3082, 2018 | 309 | 2018 |
Dissociation of tau toxicity and phosphorylation: role of GSK-3β, MARK and Cdk5 in a Drosophila model S Chatterjee, TK Sang, GM Lawless, GR Jackson Human molecular genetics 18 (1), 164-177, 2009 | 192 | 2009 |
A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine TK Sang, HY Chang, GM Lawless, A Ratnaparkhi, L Mee, LC Ackerson, ... Journal of Neuroscience 27 (5), 981-992, 2007 | 173 | 2007 |
Drosophila models of neurodegenerative disease TK Sang, GR Jackson NeuroRx 2, 438-446, 2005 | 169 | 2005 |
A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration SL Karsten, TK Sang, LT Gehman, S Chatterjee, J Liu, GM Lawless, ... Neuron 51 (5), 549-560, 2006 | 154 | 2006 |
Population structure of the Japanese eel, Anguilla japonica. TK Sang, HY Chang, CT Chen, CF Hui Molecular Biology and Evolution 11 (2), 250-260, 1994 | 147 | 1994 |
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis TK Sang, C Li, W Liu, A Rodriguez, JM Abrams, SL Zipursky, GR Jackson Human molecular genetics 14 (3), 357-372, 2005 | 67 | 2005 |
Hydrolethalus syndrome is caused by a missense mutation in a novel gene HYLS1 L Mee, H Honkala, O Kopra, J Vesa, S Finnilä, I Visapää, TK Sang, ... Human molecular genetics 14 (11), 1475-1488, 2005 | 58 | 2005 |
Pathogenic VCP/TER94 Alleles Are Dominant Actives and Contribute to Neurodegeneration by Altering Cellular ATP Level in a Drosophila IBMPFD Model YC Chang, WT Hung, YC Chang, HC Chang, CL Wu, AS Chiang, ... PLoS genetics 7 (2), e1001288, 2011 | 55 | 2011 |
Untangling the Tauopathy for Alzheimer’s disease and parkinsonism HY Chang, TK Sang, AS Chiang Journal of biomedical science 25 (1), 54, 2018 | 52 | 2018 |
Eyes closed, a Drosophila p47 homolog, is essential for photoreceptor morphogenesis TK Sang, DF Ready Oxford University Press for The Company of Biologists Limited 129 (1), 143-154, 2002 | 44 | 2002 |
Reduced neuronal expression of ribose‐5‐phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in Drosophila CT Wang, YC Chen, YY Wang, MH Huang, TL Yen, H Li, CJ Liang, ... Aging cell 11 (1), 93-103, 2012 | 38 | 2012 |
Cellular DNA contents and cell volumes of batoids HY Chang, TK Sang, KY Jan, CT Chen Copeia, 571-576, 1995 | 27 | 1995 |
Derlin-1 regulates mutant VCP-linked pathogenesis and endoplasmic reticulum stress-induced apoptosis CJ Liang, YC Chang, HC Chang, CK Wang, YC Hung, YE Lin, CC Chan, ... Plos Genetics 10 (9), e1004675, 2014 | 21 | 2014 |
Cardiac-Restricted Expression of VCP/TER94 RNAi or Disease Alleles Perturbs Drosophila Heart Structure and Impairs Function MC Viswanathan, AC Blice-Baum, TK Sang, A Cammarato Journal of cardiovascular development and disease 3 (2), 19, 2016 | 16 | 2016 |
Ecdysone-Induced Receptor Tyrosine Phosphatase PTP52F Regulates Drosophila Midgut Histolysis by Enhancement of Autophagy and Apoptosis A Santhanam, WH Peng, YT Yu, TK Sang, GC Chen, TC Meng Molecular and Cellular Biology 34 (9), 1594-1606, 2014 | 16 | 2014 |
Cleavage of human tau at Asp421 inhibits hyperphosphorylated tau induced pathology in a Drosophila model H Chi, L Sun, RH Shiu, R Han, CP Hsieh, TM Wei, CC Lo, HY Chang, ... Scientific Reports 10 (1), 13482, 2020 | 9 | 2020 |
Proteomic analysis of a drosophila IBMPFD model reveals potential pathogenic mechanisms HT Chan, TR Lee, SH Huang, HY Lee, T Sang, HL Chan, PC Lyu Molecular BioSystems 8 (6), 1730-1741, 2012 | 8 | 2012 |
VCP maintains nuclear size by regulating the DNA damage-associated MDC1–p53–autophagy axis in Drosophila YC Chang, YX Peng, BH Yu, HC Chang, PS Liang, TY Huang, CJ Shih, ... Nature Communications 12 (1), 4258, 2021 | 6 | 2021 |