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Emily Pfeiffer Kaushik
Emily Pfeiffer Kaushik
Takeda
Adresse e-mail validée de alum.mit.edu - Page d'accueil
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Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response
I Banerjee, J Zhang, T Moore-Morris, E Pfeiffer, KS Buchholz, A Liu, ...
PLoS genetics 10 (2), e1004114, 2014
1532014
Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization
JT Morgan, ER Pfeiffer, TL Thirkill, P Kumar, G Peng, HN Fridolfsson, ...
Molecular biology of the cell 22 (22), 4324-4334, 2011
1392011
Biomechanics of cardiac electromechanical coupling and mechanoelectric feedback
ER Pfeiffer, JR Tangney, JH Omens, AD McCulloch
Journal of biomechanical engineering 136 (2), 021007, 2014
1292014
Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model
RC Lyon, V Mezzano, AT Wright, E Pfeiffer, J Chuang, K Banares, ...
Human molecular genetics 23 (5), 1134-1150, 2014
1042014
High Throughput Measurement of Ca++ Dynamics in Human Stem Cell-Derived Cardiomyocytes by Kinetic Image Cytometery: A Cardiac Risk Assessment …
HR Lu, R Whittaker, JH Price, R Vega, ER Pfeiffer, F Cerignoli, R Towart, ...
Toxicological Sciences 148 (2), 503-516, 2015
952015
The effects of glycosaminoglycan content on the compressive modulus of cartilage engineered in type II collagen scaffolds
E Pfeiffer, SM Vickers, E Frank, AJ Grodzinsky, M Spector
Osteoarthritis and Cartilage 16 (10), 1237-1244, 2008
782008
Caveolae in ventricular myocytes are required for stretch-dependent conduction slowing
ER Pfeiffer, AT Wright, AG Edwards, JC Stowe, K McNall, J Tan, ...
Journal of Molecular and Cellular Cardiology 76, 265-274, 2014
542014
Desmosomal junctions are necessary for adult sinus node function
V Mezzano, Y Liang, AT Wright, RC Lyon, E Pfeiffer, MY Song, Y Gu, ...
Cardiovascular research 111 (3), 274-286, 2016
462016
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations
G Gintant, EP Kaushik, T Feaster, S Stoelzle-Feix, Y Kanda, T Osada, ...
Regulatory toxicology and pharmacology 117, 104756, 2020
342020
Specific prediction of clinical QT prolongation by kinetic image cytometry in human stem cell derived cardiomyocytes
ER Pfeiffer, R Vega, PM McDonough, JH Price, R Whittaker
Journal of pharmacological and toxicological methods 81, 263-273, 2016
342016
Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms
ER Pfeiffer-Kaushik, GL Smith, B Cai, GT Dempsey, MP Hortigon-Vinagre, ...
Journal of pharmacological and toxicological methods 99, 106612, 2019
312019
Increased cell membrane capacitance is the dominant mechanism of stretch-dependent conduction slowing in the rabbit heart: a computational study
BL Oliveira, ER Pfeiffer, J Sundnes, ST Wall, AD McCulloch
Cellular and molecular bioengineering 8, 237-246, 2015
152015
Cell-based two-dimensional morphological assessment system to predict cancer drug-induced cardiotoxicity using human induced pluripotent stem cell-derived cardiomyocytes
T Matsui, K Miyamoto, K Yamanaka, Y Okai, EP Kaushik, K Harada, ...
Toxicology and Applied Pharmacology 383, 114761, 2019
132019
Calcium regulation of an actin spring
BK Tam, JH Shin, E Pfeiffer, P Matsudaira, L Mahadevan
Biophysical journal 97 (4), 1125-1129, 2009
92009
Gaining Efficiency in Clinical Trials With Cardiac Biomarkers: JACC Review Topic of the Week
JL Januzzi Jr, JM Canty, S Das, CR DeFilippi, GA Gintant, DE Gutstein, ...
Journal of the American College of Cardiology 77 (15), 1922-1933, 2021
72021
Video-based assessment of drug-induced effects on contractile motion properties using human induced pluripotent stem cell-derived cardiomyocytes
Y Okai, K Matsune, K Yamanaka, T Matsui, EP Kaushik, K Harada, ...
Journal of Pharmacological and Toxicological Methods 105, 106893, 2020
52020
Kinetic image cytometry for predicting arrhythmias using human stem cell-derived cardiomyocytes
ER Pfeiffer, R Whittaker, R Vega, F Cerignoli, PM McDonough, JH Price
Stem Cell-Derived Models in Toxicology, 153-171, 2017
22017
Strain-dependent stretch-activated ion channel in Hodgkin-Huxley-form models of ventricular cardiomyocyte action potential
C Villongco, E Pfeiffer
BENG 260 Neurodynamics University of California San Diego, 2010
12010
15.4 The effects of glycosaminoglycan content on the compressive modulus of chondrocyte-seeded type II collagen scaffolds
E Pfeiffer, SM Vickers, E Frank, A Grodzinsky, M Spector
Osteoarthritis and Cartilage, B71, 2007
12007
Lifetime Prediction of Glass Fiber/DERAKANE 411-350 Composites
E Pfeiffer, SW Case, JJ Lesko, J Moore, N Verghese, J Bicerano, H Pham
ANTEC-CONFERENCE PROCEEDINGS- 3, 3020-3024, 2004
12004
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