| CRISPR immunity relies on the consecutive binding and degradation of negatively supercoiled invader DNA by Cascade and Cas3 ER Westra, PBG van Erp, T Künne, SP Wong, RHJ Staals, CLC Seegers, ... Molecular cell 46 (5), 595-605, 2012 | 737 | 2012 |
| The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity ER Westra, DC Swarts, RHJ Staals, MM Jore, SJJ Brouns, J van der Oost Annual review of genetics 46, 311-339, 2012 | 401 | 2012 |
| Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species A Pawluk, RHJ Staals, C Taylor, BNJ Watson, S Saha, PC Fineran, ... Nature microbiology 1 (8), 1-6, 2016 | 350 | 2016 |
| RNA Targeting by the Type III-A CRISPR-Cas Csm Complex of Thermus thermophilus RHJ Staals, Y Zhu, DW Taylor, JE Kornfeld, K Sharma, A Barendregt, ... Molecular cell 56 (4), 518-530, 2014 | 338 | 2014 |
| CRISPRDetect: a flexible algorithm to define CRISPR arrays A Biswas, RHJ Staals, SE Morales, PC Fineran, CM Brown BMC genomics 17 (1), 1-14, 2016 | 318 | 2016 |
| Degenerate target sites mediate rapid primed CRISPR adaptation PC Fineran, MJH Gerritzen, M Suárez-Diez, T Künne, J Boekhorst, ... Proceedings of the National Academy of Sciences 111 (16), E1629-E1638, 2014 | 295 | 2014 |
| Structure and activity of the RNA-targeting Type III-B CRISPR-Cas complex of Thermus thermophilus RHJ Staals, Y Agari, S Maki-Yonekura, Y Zhu, DW Taylor, E van Duijn, ... Molecular cell 52 (1), 135-145, 2013 | 283 | 2013 |
| Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility D Astuti, MR Morris, WN Cooper, RHJ Staals, NC Wake, GA Fews, H Gill, ... Nature genetics 44 (3), 277-284, 2012 | 266 | 2012 |
| The role of CRISPR-Cas systems in virulence of pathogenic bacteria R Louwen, RHJ Staals, HP Endtz, P van Baarlen, J van der Oost Microbiology and Molecular Biology Reviews 78 (1), 74-88, 2014 | 255 | 2014 |
| Priming in the Type IF CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer C Richter, RL Dy, RE McKenzie, BNJ Watson, C Taylor, JT Chang, ... Nucleic acids research 42 (13), 8516-8526, 2014 | 222 | 2014 |
| Quorum sensing controls adaptive immunity through the regulation of multiple CRISPR-Cas systems AG Patterson, SA Jackson, C Taylor, GB Evans, GPC Salmond, ... Molecular Cell 64 (6), 1102-1108, 2016 | 210 | 2016 |
| Ethylene regulates fast apoplastic acidification and expansin A transcription during submergence‐induced petiole elongation in Rumex palustris RAM Vreeburg, JJ Benschop, AJM Peeters, TD Colmer, AHM Ammerlaan, ... The Plant Journal 43 (4), 597-610, 2005 | 172 | 2005 |
| Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning DW Taylor, Y Zhu, RHJ Staals, JE Kornfeld, A Shinkai, J van der Oost, ... Science 348 (6234), 581-585, 2015 | 168 | 2015 |
| Dis3‐like 1: a novel exoribonuclease associated with the human exosome RHJ Staals, AW Bronkhorst, G Schilders, S Slomovic, G Schuster, ... The EMBO journal 29 (14), 2358-2367, 2010 | 155 | 2010 |
| Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system RHJ Staals, SA Jackson, A Biswas, SJJ Brouns, CM Brown, PC Fineran Nature communications 7 (1), 12853, 2016 | 153 | 2016 |
| The Cpf1 CRISPR-Cas protein expands genome-editing tools RD Fagerlund, RHJ Staals, PC Fineran Genome biology 16 (1), 1-3, 2015 | 130 | 2015 |
| Spacer capture and integration by a type IF Cas1–Cas2-3 CRISPR adaptation complex RD Fagerlund, ME Wilkinson, O Klykov, A Barendregt, FG Pearce, ... Proceedings of the National Academy of Sciences 114 (26), E5122-E5128, 2017 | 114 | 2017 |
| CRISPR-Cas-mediated phage resistance enhances horizontal gene transfer by transduction BNJ Watson, RHJ Staals, PC Fineran MBio 9 (1), 10.1128/mbio. 02406-17, 2018 | 103 | 2018 |
| Keeping crispr in check: diverse mechanisms of phage-encoded anti-crisprs D Trasanidou, AS Geros, P Mohanraju, AC Nieuwenweg, FL Nobrega, ... FEMS microbiology letters 366 (9), fnz098, 2019 | 81 | 2019 |
| Keeping crispr in check: diverse mechanisms of phage-encoded anti-crisprs D Trasanidou, AS Geros, P Mohanraju, AC Nieuwenweg, FL Nobrega, ... FEMS microbiology letters 366 (9), fnz098, 2019 | 81 | 2019 |
