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Paul J. Carter
Paul J. Carter
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Humanization of an anti-p185HER2 antibody for human cancer therapy.
P Carter, LEN Presta, CM Gorman, JB Ridgway, D Henner, WL Wong, ...
Proceedings of the National Academy of Sciences 89 (10), 4285-4289, 1992
30381992
Potent antibody therapeutics by design
PJ Carter
Nature reviews immunology 6 (5), 343-357, 2006
16662006
Hydrogen bonding and biological specificity analysed by protein engineering
AR Fersht, JP Shi, J Knill-Jones, DM Lowe, AJ Wilkinson, DM Blow, ...
Nature 314 (6008), 235-238, 1985
13381985
Improving the efficacy of antibody-based cancer therapies
P Carter
Nature Reviews Cancer 1 (2), 118-129, 2001
13262001
Therapeutic antibodies for autoimmunity and inflammation
AC Chan, PJ Carter
Nature reviews immunology 10 (5), 301-316, 2010
11542010
‘Knobs-into-holes’ engineering of antibody CH3 domains for heavy chain heterodimerization
JBB Ridgway, LG Presta, P Carter
Protein Engineering, Design and Selection 9 (7), 617-621, 1996
10811996
Dissecting the catalytic triad of a serine protease
P Carter, JA Wells
Nature 332 (6164), 564-568, 1988
8691988
An efficient route to human bispecific IgG
AM Merchant, Z Zhu, JQ Yuan, A Goddard, CW Adams, LG Presta, ...
Nature biotechnology 16 (7), 677-681, 1998
8241998
Improved oligonudeotide site-directed rautagenesis using M13 vectors
P Carter, H Bedouelle, G Winter
Nucleic Acids Research 13 (12), 4431-4443, 1985
8011985
Alternative molecular formats and therapeutic applications for bispecific antibodies
C Spiess, Q Zhai, PJ Carter
Molecular immunology 67 (2), 95-106, 2015
7222015
The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)
PJ Carter, G Winter, AJ Wilkinson, AR Fersht
Cell 38 (3), 835-840, 1984
7061984
Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies
GD Lewis, I Figari, B Fendly, W Lee Wong, P Carter, C Gorman, ...
Cancer Immunology, Immunotherapy 37, 255-263, 1993
6951993
Next generation antibody drugs: pursuit of the 'high-hanging fruit'
GA Carter, P. J. and Lazar
Nature Reviews Drug Discovery 17, 197-223, 2018
6932018
Sterically stabilized anti-HER2 immunoliposomes: design and targeting to human breast cancer cells in vitro
D Kirpotin, JW Park, K Hong, S Zalipsky, WL Li, P Carter, CC Benz, ...
Biochemistry 36 (1), 66-75, 1997
6361997
High Level Escherichia coli Expression and Production of a Bivalent Humanized Antibody Fragment
P Carter, RF Kelley, ML Rodrigues, B Snedecor, M Covarrubias, ...
Bio/technology 10 (2), 163-167, 1992
6311992
Introduction to current and future protein therapeutics: a protein engineering perspective
PJ Carter
Experimental cell research 317 (9), 1261-1269, 2011
6112011
Antibody-drug conjugates for cancer therapy
PJ Carter, PD Senter
The Cancer Journal 14 (3), 154-169, 2008
5142008
Development of anti-p185HER2 immunoliposomes for cancer therapy.
JW Park, K Hong, P Carter, H Asgari, LY Guo, GA Keller, C Wirth, ...
Proceedings of the National Academy of Sciences 92 (5), 1327-1331, 1995
4801995
Site-directed mutagenesis.
P Carter
Biochemical Journal 237 (1), 1, 1986
4791986
Bispecific human IgG by design
P Carter
Journal of immunological methods 248 (1-2), 7-15, 2001
3832001
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