Thomas Zichner
Thomas Zichner
Distinguished Scientist, Boehringer Ingelheim RCV, Austria
Verified email at embl.de
TitleCited byYear
An integrated map of structural variation in 2,504 human genomes
PH Sudmant, T Rausch, EJ Gardner, RE Handsaker, A Abyzov, ...
Nature 526 (7571), 75, 2015
9812015
DELLY: structural variant discovery by integrated paired-end and split-read analysis
T Rausch, T Zichner, A Schlattl, AM Stütz, V Benes, JO Korbel
Bioinformatics 28 (18), i333-i339, 2012
8132012
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100, 2012
6442012
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1), 59-71, 2012
5902012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49, 2012
5782012
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927, 2013
4672013
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445, 2014
3902014
The genomic and transcriptomic landscape of a HeLa cell line
JJM Landry, PT Pyl, T Rausch, T Zichner, MM Tekkedil, AM Stütz, A Jauch, ...
G3: Genes, Genomes, Genetics 3 (8), 1213-1224, 2013
3642013
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
W Huang, A Massouras, Y Inoue, J Peiffer, M Ràmia, AM Tarone, ...
Genome research 24 (7), 1193-1208, 2014
3482014
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ...
Nature 511 (7510), 428, 2014
2952014
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer
J Weischenfeldt, R Simon, L Feuerbach, K Schlangen, D Weichenhan, ...
Cancer cell 23 (2), 159-170, 2013
2652013
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311, 2017
2242017
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
J Weischenfeldt, T Dubash, AP Drainas, BR Mardin, Y Chen, AM Stütz, ...
Nature genetics 49 (1), 65, 2017
1262017
Shadow enhancers are pervasive features of developmental regulatory networks
E Cannavò, P Khoueiry, DA Garfield, P Geeleher, T Zichner, ...
Current Biology 26 (1), 38-51, 2016
1072016
Identifying the unknowns by aligning fragmentation trees
F Rasche, K Scheubert, F Hufsky, T Zichner, M Kai, A Svatoš, S Böcker
Analytical chemistry 84 (7), 3417-3426, 2012
962012
Genomics and drug profiling of fatal TCF3-HLF−positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options
U Fischer, M Forster, A Rinaldi, T Risch, S Sungalee, HJ Warnatz, ...
Nature genetics 47 (9), 1020, 2015
892015
Algorithm engineering for color-coding with applications to signaling pathway detection
F Hüffner, S Wernicke, T Zichner
Algorithmica 52 (2), 114-132, 2008
722008
Impact of genomic structural variation in Drosophila melanogaster based on population-scale sequencing
T Zichner, DA Garfield, T Rausch, AM Stütz, E Cannavó, M Braun, ...
Genome research 23 (3), 568-579, 2013
632013
Systematic inference of copy-number genotypes from personal genome sequencing data reveals extensive olfactory receptor gene content diversity
SM Waszak, Y Hasin, T Zichner, T Olender, I Keydar, M Khen, AM Stütz, ...
PLoS computational biology 6 (11), e1000988, 2010
632010
Recurrent MET fusion genes represent a drug target in pediatric glioblastoma
S Bender, J Gronych, HJ Warnatz, B Hutter, S Gröbner, M Ryzhova, ...
Nature medicine 22 (11), 1314, 2016
562016
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