How cells respond to interferons GR Stark, IM Kerr, BRG Williams, RH Silverman, RD Schreiber Annual review of biochemistry 67 (1), 227-264, 1998 | 5212 | 1998 |
Interferon-inducible antiviral effectors AJ Sadler, BRG Williams Nature reviews immunology 8 (7), 559-568, 2008 | 2562 | 2008 |
Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays SD Der, A Zhou, BRG Williams, RH Silverman Proceedings of the National Academy of Sciences 95 (26), 15623-15628, 1998 | 2370 | 1998 |
Activation of the interferon system by short-interfering RNAs CA Sledz, M Holko, MJ De Veer, RH Silverman, BRG Williams Nature cell biology 5 (9), 834-839, 2003 | 1957 | 2003 |
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon E Meurs, K Chong, J Galabru, NSB Thomas, IM Kerr, BRG Williams, ... Cell 62 (2), 379-390, 1990 | 1279 | 1990 |
Functional classification of interferon-stimulated genes identified using microarrays MJ de Veer, M Holko, M Frevel, E Walker, S Der, JM Paranjape, ... Journal of leukocyte biology 69 (6), 912-920, 2001 | 1239 | 2001 |
PKR; a sentinel kinase for cellular stress BRG Williams Oncogene 18 (45), 6112-6120, 1999 | 1143 | 1999 |
Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis M Chawla-Sarkar, DJ Lindner, YF Liu, BR Williams, GC Sen, ... Apoptosis 8, 237-249, 2003 | 1112 | 2003 |
TLR4, but not TLR2, mediates IFN-β–induced STAT1α/β-dependent gene expression in macrophages V Toshchakov, BW Jones, PY Perera, K Thomas, MJ Cody, S Zhang, ... Nature immunology 3 (4), 392-398, 2002 | 1030 | 2002 |
Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase. YL Yang, LF Reis, J Pavlovic, A Aguzzi, R Schäfer, A Kumar, BR Williams, ... The EMBO journal 14 (24), 6095-6106, 1995 | 821 | 1995 |
Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. A Kumar, J Haque, J Lacoste, J Hiscott, BR Williams Proceedings of the National Academy of Sciences 91 (14), 6288-6292, 1994 | 761 | 1994 |
Biological properties of recombinant α-interferons: 40th anniversary of the discovery of interferons LM Pfeffer, CA Dinarello, RB Herberman, BRG Williams, EC Borden, ... Cancer research 58 (12), 2489-2499, 1998 | 672 | 1998 |
Neutralising antibody activity against SARS-CoV-2 VOCs B. 1.617. 2 and B. 1.351 by BNT162b2 vaccination EC Wall, M Wu, R Harvey, G Kelly, S Warchal, C Sawyer, R Daniels, ... The Lancet 397 (10292), 2331-2333, 2021 | 597 | 2021 |
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis SD Der, YL Yang, C Weissmann, BRG Williams Proceedings of the National Academy of Sciences 94 (7), 3279-3283, 1997 | 558 | 1997 |
Inhibition of cell-free protein synthesis by pppA2′ p5′ A2′ p5′ A: a novel oligonucleotide synthesized by interferon-treated L cell extracts MJ Clemens, BRG Williams Cell 13 (3), 565-572, 1978 | 541 | 1978 |
JNK2 and IKKβ are required for activating the innate response to viral infection WM Chu, D Ostertag, ZW Li, L Chang, Y Chen, Y Hu, B Williams, ... Immunity 11 (6), 721-731, 1999 | 537 | 1999 |
Signal integration via PKR BRG Williams Science's STKE 2001 (89), re2-re2, 2001 | 533 | 2001 |
ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins T Bakheet, M Frevel, BRG Williams, W Greer, KSA Khabar Nucleic acids research 29 (1), 246-254, 2001 | 521 | 2001 |
A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells JT Marques, T Devosse, D Wang, M Zamanian-Daryoush, P Serbinowski, ... Nature biotechnology 24 (5), 559-565, 2006 | 512 | 2006 |
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons KC Goh, SJ Haque, BRG Williams The EMBO journal, 1999 | 499 | 1999 |