Charles Brenner
Charles Brenner
Alfred E Mann Chair of Diabetes & Cancer Metabolism, Beckman Research Inst at City of Hope
Verified email at - Homepage
Cited by
Cited by
p53 activation by knockdown technologies
ME Robu, JD Larson, A Nasevicius, S Beiraghi, C Brenner, SA Farber, ...
PLOS genet 3 (5), e78, 2007
NAD+ metabolism in health and disease
P Belenky, KL Bogan, C Brenner
Trends in biochemical sciences 32 (1), 12-19, 2007
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
P Bieganowski, C Brenner
Cell 117 (4), 495-502, 2004
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast
AB Parsons, A Lopez, IE Givoni, DE Williams, CA Gray, J Porter, G Chua, ...
Cell 126 (3), 611-625, 2006
Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition
KL Bogan, C Brenner
Annu. Rev. Nutr. 28, 115-130, 2008
The nitrilase superfamily: classification, structure and function
HC Pace, C Brenner
Genome biology 2 (1), 1-9, 2001
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction
I Miyajima, M Nakafuku, N Nakayama, C Brenner, A Miyajima, K Kaibuchi, ...
Cell 50 (7), 1011-1019, 1987
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
P Belenky, FG Racette, KL Bogan, JM McClure, JS Smith, C Brenner
Cell 129 (3), 473-484, 2007
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
SAJ Trammell, MS Schmidt, BJ Weidemann, P Redpath, F Jaksch, ...
Nature communications 7 (1), 1-14, 2016
Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases
C Brenner
Biochemistry 41 (29), 9003-9014, 2002
Catalysis in the nitrilase superfamily
C Brenner
Current opinion in structural biology 12 (6), 775-782, 2002
Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease.
C Brenner, RS Fuller
Proceedings of the National Academy of Sciences 89 (3), 922-926, 1992
The ataxia–oculomotor apraxia 1 gene product has a role distinct from ATM and interacts with the DNA strand break repair proteins XRCC1 and XRCC4
PM Clements, C Breslin, ED Deeks, PJ Byrd, L Ju, P Bieganowski, ...
DNA repair 3 (11), 1493-1502, 2004
Scaffolding Functions of Arrestin-2 Revealed by Crystal Structure and Mutagenesis,
SK Milano, HC Pace, YM Kim, C Brenner, JL Benovic
Biochemistry 41 (10), 3321-3328, 2002
Arabidopsis VTC2 encodes a GDP-L-galactose phosphorylase, the last unknown enzyme in the Smirnoff-Wheeler pathway to ascorbic acid in plants
CL Linster, TA Gomez, KC Christensen, LN Adler, BD Young, C Brenner, ...
Journal of Biological Chemistry 282 (26), 18879-18885, 2007
Genetic, biochemical, and crystallographic characterization of Fhit–substrate complexes as the active signaling form of Fhit
HC Pace, PN Garrison, AK Robinson, LD Barnes, A Draganescu, ...
Proceedings of the National Academy of Sciences 95 (10), 5484-5489, 1998
Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins
C Brenner, P Garrison, J Gilmour, D Peisach, D Ringe, GA Petsko, ...
Nature structural biology 4 (3), 231-238, 1997
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
J Ratajczak, M Joffraud, SAJ Trammell, R Ras, N Canela, M Boutant, ...
Nature communications 7 (1), 1-12, 2016
The histidine triad superfamily of nucleotide‐binding proteins
C Brenner, P Bieganowski, HC Pace, K Huebner
Journal of cellular physiology 181 (2), 179-187, 1999
Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice
SAJ Trammell, BJ Weidemann, A Chadda, MS Yorek, A Holmes, ...
Scientific reports 6 (1), 1-7, 2016
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