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Charles Brenner
Charles Brenner
Alfred E Mann Family Foundation Chair, Beckman Research Inst at City of Hope
Verified email at coh.org - Homepage
Title
Cited by
Cited by
Year
p53 activation by knockdown technologies
ME Robu, JD Larson, A Nasevicius, S Beiraghi, C Brenner, SA Farber, ...
PLoS genetics 3 (5), e78, 2007
11792007
NAD+ metabolism in health and disease
P Belenky, KL Bogan, C Brenner
Trends in biochemical sciences 32 (1), 12-19, 2007
11312007
Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
P Bieganowski, C Brenner
Cell 117 (4), 495-502, 2004
8022004
Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition
KL Bogan, C Brenner
Annu. Rev. Nutr. 28, 115-130, 2008
7302008
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
SAJ Trammell, MS Schmidt, BJ Weidemann, P Redpath, F Jaksch, ...
Nature communications 7 (1), 12948, 2016
6142016
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast
AB Parsons, A Lopez, IE Givoni, DE Williams, CA Gray, J Porter, G Chua, ...
Cell 126 (3), 611-625, 2006
5542006
The nitrilase superfamily: classification, structure and function
HC Pace, C Brenner
Genome biology 2, 1-9, 2001
4652001
Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
P Belenky, FG Racette, KL Bogan, JM McClure, JS Smith, C Brenner
Cell 129 (3), 473-484, 2007
4492007
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction
I Miyajima, M Nakafuku, N Nakayama, C Brenner, A Miyajima, K Kaibuchi, ...
Cell 50 (7), 1011-1019, 1987
4131987
Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases
C Brenner
Biochemistry 41 (29), 9003-9014, 2002
3372002
Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice
SAJ Trammell, BJ Weidemann, A Chadda, MS Yorek, A Holmes, ...
Scientific reports 6 (1), 26933, 2016
3152016
Circadian reprogramming in the liver identifies metabolic pathways of aging
S Sato, G Solanas, FO Peixoto, L Bee, A Symeonidi, MS Schmidt, ...
Cell 170 (4), 664-677. e11, 2017
3102017
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
J Ratajczak, M Joffraud, SAJ Trammell, R Ras, N Canela, M Boutant, ...
Nature communications 7 (1), 13103, 2016
3082016
Nicotinamide improves aspects of healthspan, but not lifespan, in mice
SJ Mitchell, M Bernier, MA Aon, S Cortassa, EY Kim, EF Fang, ...
Cell metabolism 27 (3), 667-676. e4, 2018
3022018
Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures
YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ...
Cell reports 28 (7), 1717-1728. e6, 2019
3012019
Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy
N Diguet, SAJ Trammell, C Tannous, R Deloux, J Piquereau, N Mougenot, ...
Circulation 137 (21), 2256-2273, 2018
2972018
Catalysis in the nitrilase superfamily
C Brenner
Current opinion in structural biology 12 (6), 775-782, 2002
2792002
A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects
OL Dollerup, B Christensen, M Svart, MS Schmidt, K Sulek, S Ringgaard, ...
The American journal of clinical nutrition 108 (2), 343-353, 2018
2482018
Structural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 protease.
C Brenner, RS Fuller
Proceedings of the National Academy of Sciences 89 (3), 922-926, 1992
2441992
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
AJ Covarrubias, A Kale, R Perrone, JA Lopez-Dominguez, AO Pisco, ...
Nature metabolism 2 (11), 1265-1283, 2020
2342020
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