Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning D Vitsios, RS Dhindsa, L Middleton, AB Gussow, S Petrovski Nature communications 12 (1), 1504, 2021 | 50 | 2021 |
Unbiased Markov chain Monte Carlo for intractable target distributions L Middleton, G Deligiannidis, A Doucet, PE Jacob | 32 | 2020 |
Unbiased smoothing using particle independent Metropolis-Hastings L Middleton, G Deligiannidis, A Doucet, PE Jacob The 22nd International Conference on Artificial Intelligence and Statistics …, 2019 | 25 | 2019 |
Assessing the contribution of rare-to-common protein-coding variants to circulating metabolic biomarker levels via 412,394 UK Biobank exome sequences A Nag, L Middleton, RS Dhindsa, D Vitsios, E Wigmore, EL Allman, ... MedRxiv, 2021.12. 24.21268381, 2021 | 12 | 2021 |
DrugnomeAI is an ensemble machine-learning framework for predicting druggability of candidate drug targets A Raies, E Tulodziecka, J Stainer, L Middleton, RS Dhindsa, P Hill, ... Communications Biology 5 (1), 1291, 2022 | 10 | 2022 |
Effects of protein-coding variants on blood metabolite measurements and clinical biomarkers in the UK Biobank A Nag, RS Dhindsa, L Middleton, X Jiang, D Vitsios, E Wigmore, ... The American Journal of Human Genetics 110 (3), 487-498, 2023 | 6 | 2023 |
Gene-SCOUT: identifying genes with similar continuous trait fingerprints from phenome-wide association analyses L Middleton, AR Harper, A Nag, Q Wang, A Reznichenko, D Vitsios, ... Nucleic Acids Research 50 (8), 4289-4301, 2022 | 4 | 2022 |
Analysis of 983 civilian blast and ballistic casualties and the generation of a template of injury burden: An observational study L Maitland, L Middleton, H Veen, DJ Harrison, J Baden, S Hettiaratchy EClinicalMedicine 54, 2022 | 2 | 2022 |
Applying Machine Learning on UK Biobank biomarker data empowers case-control discovery yield M Garg, M Karpinski, D Matelska, L Middleton, J Mitchell, A O'Neill, ... medRxiv, 2023.10. 10.23296832, 2023 | | 2023 |
Assessing the role of rare pathogenic variants in heart failure progression by exome sequencing in 8,089 patients O Chazara, MP Dubé, Q Wang, L Middleton, D Vitsios, A Walentinsson, ... medRxiv, 2023.07. 28.23293350, 2023 | | 2023 |
Trading styles and long-run variance of asset prices L Middleton, J Dodd, S Rijavec arXiv preprint arXiv:2109.08242, 2021 | | 2021 |
Scalable inference in state-space models L Middleton University of Oxford, 2019 | | 2019 |