|Production of reactive oxygen species, alteration of cytosolic ascorbate peroxidase, and impairment of mitochondrial metabolism are early events in heat shock-induced …|
RA Vacca, MC de Pinto, D Valenti, S Passarella, E Marra, L De Gara
Plant physiology 134 (3), 1100-1112, 2004
|Cytochrome c is released in a reactive oxygen species-dependent manner and is degraded via caspase-like proteases in tobacco Bright-Yellow 2 cells en route to heat shock …|
RA Vacca, D Valenti, A Bobba, RS Merafina, S Passarella, E Marra
Plant Physiology 141 (1), 208-219, 2006
|Mitochondrial dysfunction as a central actor in intellectual disability-related diseases: an overview of Down syndrome, autism, Fragile X and Rett syndrome|
D Valenti, L de Bari, B De Filippis, A Henrion-Caude, RA Vacca
Neuroscience & Biobehavioral Reviews 46, 202-217, 2014
|Deficit of complex I activity in human skin fibroblasts with chromosome 21 trisomy and overproduction of reactive oxygen species by mitochondria: involvement of cAMP/PKA …|
D Valenti, GA Manente, L Moro, E Marra, RA Vacca
Portland Press Limited, 2011
|Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome|
D Valenti, D De Rasmo, A Signorile, L Rossi, L de Bari, I Scala, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (4), 542-552, 2013
|Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention|
D Tewari, SF Nabavi, SM Nabavi, A Sureda, AA Farooqi, AG Atanasov, ...
Pharmacological Research 128, 366-375, 2018
|The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model|
D Valenti, L de Bari, D de Rasmo, A Signorile, A Henrion-Caude, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (6 …, 2016
|Therapeutic role of sirtuins in neurodegenerative disease and their modulation by polyphenols|
M Ajami, H Pazoki-Toroudi, H Amani, SF Nabavi, N Braidy, RA Vacca, ...
Neuroscience & Biobehavioral Reviews 73, 39-47, 2017
|Helium‐Neon laser irradiation of hepatocytes can trigger increase of the mitochondrial membrane potential and can stimulate c‐fos expression in a Ca2+‐dependent manner|
M Greco, RA Vacca, L Moro, E Perlino, VA Petragallo, E Marra, ...
Lasers in Surgery and Medicine: The Official Journal of the American Society …, 2001
|Impairment of ATPase, adenine nucleotide translocator, and adenylate kinase causes mitochondrial energy deficit in human skin fibroblasts with chromosome 21 trisomy|
D Valenti, A Tullo, MF Caratozzolo, RS Merafina, P Scartezzini, E Marra, ...
Portland Press Limited, 2010
|Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1|
B De Filippis, D Valenti, L de Bari, D De Rasmo, M Musto, A Fabbri, ...
Free Radical Biology and Medicine 83, 167-177, 2015
|Regulation of mRNA and protein levels of β1 integrin variants in human prostate carcinoma|
E Perlino, M Lovecchio, RA Vacca, M Fornaro, L Moro, P Ditonno, ...
The American journal of pathology 157 (5), 1727-1734, 2000
|Activation of mitochondrial DNA replication by He-Ne laser irradiation|
RA Vacca, E Marra, E Quagliariello, M Greco
Biochemical and biophysical research communications 195 (2), 704-709, 1993
|Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells|
D Valenti, L de Bari, GA Manente, L Rossi, L Mutti, L Moro, RA Vacca
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013
|Active-site Arg→ Lys substitutions alter reaction and substrate specificity of aspartate aminotransferase|
RA Vacca, S Giannattasio, R Graber, E Sandmeier, E Marra, P Christen
Journal of Biological Chemistry 272 (35), 21932-21937, 1997
|Increase in cytosolic and mitochondrial protein synthesis in rat hepatocytes irradiated in vitro by He Ne laser|
RA Vacca, E Marra, S Passarella, VA Petragallo, M Greco
Journal of Photochemistry and Photobiology B: Biology 34 (2-3), 197-202, 1996
|Plant polyphenols as natural drugs for the management of Down syndrome and related disorders|
RA Vacca, D Valenti, S Caccamese, M Daglia, N Braidy, SM Nabavi
Neuroscience & Biobehavioral Reviews 71, 865-877, 2016
|Mitochondria as pharmacological targets in Down syndrome|
D Valenti, N Braidy, D De Rasmo, A Signorile, L Rossi, AG Atanasov, ...
Free Radical Biology and Medicine 114, 69-83, 2018
|Increase of both transcription and translation activities following separate irradiation of the in vitro system components with He-Ne laser|
RA Vacca, E Marra, E Quagliariello, M Greco
Biochemical and biophysical research communications 203 (2), 991-997, 1994
|Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells|
RA Vacca, D Valenti, A Bobba, MC de Pinto, RS Merafina, L De Gara, ...
Febs Letters 581 (5), 917-922, 2007