| A new DREADD facilitates the multiplexed chemogenetic interrogation of behavior E Vardy, JE Robinson, C Li, RHJ Olsen, JF DiBerto, PM Giguere, ... Neuron 86 (4), 936-946, 2015 | 399 | 2015 |
| Structural basis for selectivity and diversity in angiotensin II receptors H Zhang, GW Han, A Batyuk, A Ishchenko, KL White, N Patel, ... Nature 544 (7650), 327-332, 2017 | 223 | 2017 |
| Allosteric coupling of drug binding and intracellular signaling in the A2A adenosine receptor MT Eddy, MY Lee, ZG Gao, KL White, T Didenko, R Horst, M Audet, ... Cell 172 (1), 68-80. e12, 2018 | 200 | 2018 |
| The G protein–biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo KL White, JE Robinson, H Zhu, JF DiBerto, PR Polepally, JK Zjawiony, ... Journal of Pharmacology and Experimental Therapeutics 352 (1), 98-109, 2015 | 195 | 2015 |
| Structural connection between activation microswitch and allosteric sodium site in GPCR signaling KL White, MT Eddy, ZG Gao, GW Han, T Lian, A Deary, N Patel, ... Structure 26 (2), 259-269. e5, 2018 | 148 | 2018 |
| Identification of novel functionally selective κ-opioid receptor scaffolds KL White, AP Scopton, ML Rives, RV Bikbulatov, PR Polepally, PJ Brown, ... Molecular pharmacology 85 (1), 83-90, 2014 | 135 | 2014 |
| Single-molecule view of basal activity and activation mechanisms of the G protein-coupled receptor β2AR R Lamichhane, JJ Liu, G Pljevaljcic, KL White, E van der Schans, ... Proceedings of the National Academy of Sciences 112 (46), 14254-14259, 2015 | 114 | 2015 |
| Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists T Claff, J Yu, V Blais, N Patel, C Martin, L Wu, GW Han, BJ Holleran, ... Science advances 5 (11), eaax9115, 2019 | 95 | 2019 |
| NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor C O’Connor, KL White, N Doncescu, T Didenko, BL Roth, G Czaplicki, ... Proceedings of the National Academy of Sciences 112 (38), 11852-11857, 2015 | 91 | 2015 |
| Opportunities and challenges in building a spatiotemporal multi-scale model of the human pancreatic β cell J Singla, KM McClary, KL White, F Alber, A Sali, RC Stevens Cell 173 (1), 11-19, 2018 | 62 | 2018 |
| Federating structural models and data: outcomes from a workshop on archiving integrative structures HM Berman, PD Adams, AA Bonvin, SK Burley, B Carragher, W Chiu, ... Structure 27 (12), 1745-1759, 2019 | 47 | 2019 |
| Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor M Audet, KL White, B Breton, B Zarzycka, GW Han, Y Lu, C Gati, A Batyuk, ... Nature chemical biology 15 (1), 11-17, 2019 | 47 | 2019 |
| Biased signaling of the G-protein-coupled receptor β2AR is governed by conformational exchange kinetics R Lamichhane, JJ Liu, KL White, V Katritch, RC Stevens, K Wüthrich, ... Structure 28 (3), 371-377. e3, 2020 | 43 | 2020 |
| Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography KL White, J Singla, V Loconte, JH Chen, A Ekman, L Sun, X Zhang, ... Science advances 6 (50), eabc8262, 2020 | 35 | 2020 |
| In Vitro and In Vivo Characterization of the Alkaloid Nuciferine MS Farrell, JD McCorvy, XP Huang, DJ Urban, KL White, PM Giguere, ... PLoS One 11 (3), e0150602, 2016 | 35 | 2016 |
| Receptor reserve moderates mesolimbic responses to opioids in a humanized mouse model of the OPRM1 A118G polymorphism JE Robinson, E Vardy, JF DiBerto, VI Chefer, KL White, EW Fish, M Chen, ... Neuropsychopharmacology 40 (11), 2614-2622, 2015 | 35 | 2015 |
| Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes Z Wang, T Gurlo, AV Matveyenko, D Elashoff, P Wang, M Rosenberger, ... Communications biology 4 (1), 594, 2021 | 27 | 2021 |
| Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography X Zhang, SD Carter, J Singla, KL White, PC Butler, RC Stevens, ... Science Advances 6 (50), eabc8258, 2020 | 24 | 2020 |
| Bayesian metamodeling of complex biological systems across varying representations B Raveh, L Sun, KL White, T Sanyal, J Tempkin, D Zheng, K Bharath, ... Proceedings of the National Academy of Sciences 118 (35), e2104559118, 2021 | 23 | 2021 |
| Soft X-ray tomography to map and quantify organelle interactions at the mesoscale V Loconte, J Singla, A Li, JH Chen, A Ekman, G McDermott, A Sali, ... Structure 30 (4), 510-521. e3, 2022 | 22 | 2022 |
