Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer NA Zhao, J Cao, L Xu, Q Tang, LE Dobrolecki, X Lv, M Talukdar, Y Lu, ... The Journal of clinical investigation 128 (4), 1283-1299, 2018 | 178 | 2018 |
Ter94 ATPase complex targets k11-linked ubiquitinated ci to proteasomes for partial degradation Z Zhang, X Lv, W Yin, X Zhang, J Feng, W Wu, C Hui, L Zhang, Y Zhao Developmental cell 25 (6), 636-644, 2013 | 60 | 2013 |
Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction D Shi, X Lv, Z Zhang, X Yang, Z Zhou, L Zhang, Y Zhao Journal of Biological Chemistry 288 (18), 12605-12614, 2013 | 57 | 2013 |
Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover S Huang, Z Zhang, C Zhang, X Lv, X Zheng, Z Chen, L Sun, H Wang, ... PLoS biology 11 (11), e1001721, 2013 | 52 | 2013 |
Dual roles of Hh signaling in the regulation of somatic stem cell self-renewal and germline stem cell maintenance in Drosophila testis Z Zhang, X Lv, J Jiang, L Zhang, Y Zhao Cell research 23 (4), 573-576, 2013 | 49 | 2013 |
Drosophila Vps36 regulates Smo trafficking in Hedgehog signaling X Yang, F Mao, X Lv, Z Zhang, L Fu, Y Lu, W Wu, Z Zhou, L Zhang, Y Zhao Journal of cell science 126 (18), 4230-4238, 2013 | 42* | 2013 |
Chromatin Assembly Factor 1 (CAF-1) facilitates the establishment of facultative heterochromatin during pluripotency exit L Cheng, X Zhang, Y Wang, H Gan, X Xu, X Lv, X Hua, J Que, T Ordog, ... Nucleic acids research 47 (21), 11114-11131, 2019 | 38 | 2019 |
Atrophin–Rpd3 complex represses Hedgehog signaling by acting as a corepressor of CiR Z Zhang, J Feng, C Pan, X Lv, W Wu, Z Zhou, F Liu, L Zhang, Y Zhao Journal of Cell Biology 203 (4), 575-583, 2013 | 34 | 2013 |
A positive role for polycomb in transcriptional regulation via H4K20me1 X Lv, Z Han, H Chen, B Yang, X Yang, Y Xia, C Pan, L Fu, S Zhang, ... Cell research 26 (5), 529-542, 2016 | 26 | 2016 |
Gut–neuron interaction via Hh signaling regulates intestinal progenitor cell differentiation in Drosophila H Han, C Pan, C Liu, X Lv, X Yang, Y Xiong, Y Lu, W Wu, J Han, Z Zhou, ... Cell discovery 1 (1), 1-13, 2015 | 24 | 2015 |
Multiomics analyses reveal DARS1-AS1/YBX1–controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance C Zheng, Y Wei, Q Zhang, M Sun, Y Wang, J Hou, P Zhang, X Lv, D Su, ... Science advances 9 (31), eadf3984, 2023 | 18 | 2023 |
SUMO regulates somatic cyst stem cell maintenance and directly targets the Hedgehog pathway in adult Drosophila testis X Lv, C Pan, Z Zhang, Y Xia, H Chen, S Zhang, T Guo, H Han, H Song, ... Development 143 (10), 1655-1662, 2016 | 18 | 2016 |
Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β− selection X Liu, J Yu, L Xu, K Umphred-Wilson, F Peng, Y Ding, BM Barton, X Lv, ... Elife 10, e69975, 2021 | 17 | 2021 |
Systematic functional interrogation of human pseudogenes using CRISPRi M Sun, Y Wang, C Zheng, Y Wei, J Hou, P Zhang, W He, X Lv, Y Ding, ... Genome biology 22, 1-29, 2021 | 14 | 2021 |
Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors X Lv, X Lu, J Cao, Q Luo, Y Ding, F Peng, A Pataer, D Lu, D Han, ... Science 381 (6662), eabn4180, 2023 | 13 | 2023 |
Orthotopic transplantation of breast tumors as preclinical models for breast cancer X Lv, LE Dobrolecki, Y Ding, JM Rosen, MT Lewis, X Chen JoVE (Journal of Visualized Experiments), e61173, 2020 | 13 | 2020 |
Repression of Abd-B by Polycomb is critical for cell identity maintenance in adult Drosophila testis S Zhang, C Pan, X Lv, W Wu, H Chen, W Wu, H Wu, L Zhang, Y Zhao Scientific Reports 7 (1), 5101, 2017 | 12 | 2017 |
CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer C Zheng, Y Wei, P Zhang, L Xu, Z Zhang, K Lin, J Hou, X Lv, Y Ding, ... The Journal of Clinical Investigation 133 (5), 2023 | 11 | 2023 |
UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing C Pan, Y Xiong, X Lv, Y Xia, S Zhang, H Chen, J Fan, W Wu, F Liu, H Wu, ... EMBO reports 18 (11), 1922-1934, 2017 | 9 | 2017 |
Analysis on gene modular network reveals morphogen-directed development robustness in Drosophila S Zhang, J Zhao, X Lv, J Fan, Y Lu, T Zeng, H Wu, L Chen, Y Zhao Cell discovery 6 (1), 43, 2020 | 8 | 2020 |