| 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data JK Nicholson, JC Lindon, E Holmes Xenobiotica 29 (11), 1181-1189, 1999 | 4199 | 1999 |
| Host-gut microbiota metabolic interactions JK Nicholson, E Holmes, J Kinross, R Burcelin, G Gibson, W Jia, ... Science 336 (6086), 1262-1267, 2012 | 2902 | 2012 |
| Metabonomics: a platform for studying drug toxicity and gene function JK Nicholson, J Connelly, JC Lindon, E Holmes Nature reviews Drug discovery 1 (2), 153-161, 2002 | 2300 | 2002 |
| Multi-and megavariate data analysis L Eriksson, E Johansson, N Kettaneh-Wold, J Trygg, C Wikström, S Wold Umetrics 1, 1, 2006 | 2260 | 2006 |
| Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ... Nature protocols 2 (11), 2692-2703, 2007 | 1748 | 2007 |
| Chemometrics in metabonomics J Trygg, E Holmes, T Lundstedt Journal of proteome research 6 (2), 469-479, 2007 | 1305 | 2007 |
| Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1 H-NMR-based metabonomics JT Brindle, H Antti, E Holmes, G Tranter, JK Nicholson, HWL Bethell, ... Nature medicine 8 (12), 1439-1445, 2002 | 1285 | 2002 |
| 750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma JK Nicholson, PJD Foxall, M Spraul, RD Farrant, JC Lindon Analytical chemistry 67 (5), 793-811, 1995 | 1101 | 1995 |
| OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification M Bylesjö, M Rantalainen, O Cloarec, JK Nicholson, E Holmes, J Trygg Journal of Chemometrics: A Journal of the Chemometrics Society 20 (8‐10 …, 2006 | 1097 | 2006 |
| Symbiotic gut microbes modulate human metabolic phenotypes M Li, B Wang, M Zhang, M Rantalainen, S Wang, H Zhou, Y Zhang, ... Proceedings of the National Academy of Sciences 105 (6), 2117-2122, 2008 | 1065 | 2008 |
| Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice ME Dumas, RH Barton, A Toye, O Cloarec, C Blancher, A Rothwell, ... Proceedings of the national academy of sciences 103 (33), 12511-12516, 2006 | 1040 | 2006 |
| Gut microorganisms, mammalian metabolism and personalized health care JK Nicholson, E Holmes, ID Wilson Nature Reviews Microbiology 3 (5), 431-438, 2005 | 1021 | 2005 |
| Human metabolic phenotype diversity and its association with diet and blood pressure E Holmes, RL Loo, J Stamler, M Bictash, IKS Yap, Q Chan, T Ebbels, ... Nature 453 (7193), 396-400, 2008 | 1010 | 2008 |
| Gut microbiomes of Malawian twin pairs discordant for kwashiorkor MI Smith, T Yatsunenko, MJ Manary, I Trehan, R Mkakosya, J Cheng, ... Science 339 (6119), 548-554, 2013 | 946 | 2013 |
| Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets O Cloarec, ME Dumas, A Craig, RH Barton, J Trygg, J Hudson, ... Analytical chemistry 77 (5), 1282-1289, 2005 | 853 | 2005 |
| Global metabolic profiling procedures for urine using UPLC–MS EJ Want, ID Wilson, H Gika, G Theodoridis, RS Plumb, J Shockcor, ... Nature protocols 5 (6), 1005, 2010 | 687 | 2010 |
| Metabolic phenotyping in health and disease E Holmes, ID Wilson, JK Nicholson Cell 134 (5), 714-717, 2008 | 670 | 2008 |
| Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR … O Cloarec, ME Dumas, J Trygg, A Craig, RH Barton, JC Lindon, ... Analytical chemistry 77 (2), 517-526, 2005 | 593 | 2005 |
| Pattern recognition methods and applications in biomedical magnetic resonance JC Lindon Prog Nucl Mag Res Sp 39, 1-40, 2001 | 577 | 2001 |
| Systemic gut microbial modulation of bile acid metabolism in host tissue compartments JR Swann, EJ Want, FM Geier, K Spagou, ID Wilson, JE Sidaway, ... Proceedings of the National Academy of Sciences 108 (Supplement 1), 4523-4530, 2011 | 558 | 2011 |
Jeremy K NicholsonPro-Vice Chancellor, Health Sciences; Director, Australian National Phenome Center, MurdochAdresse e-mail validée de murdoch.edu.au
