Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 2629 | 2012 |
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 1952 | 2012 |
Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 962 | 2012 |
Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ... Journal of Clinical Oncology 31 (23), 2927-2935, 2013 | 510 | 2013 |
Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma AM Fontebasso, S Papillon-Cavanagh, J Schwartzentruber, H Nikbakht, ... Nature genetics 46 (5), 462-466, 2014 | 444 | 2014 |
Cytogenetic prognostication within medulloblastoma subgroups DJH Shih, PA Northcott, M Remke, A Korshunov, V Ramaswamy, M Kool, ... Journal of clinical oncology 32 (9), 886-896, 2014 | 358 | 2014 |
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis EM Thompson, T Hielscher, E Bouffet, M Remke, B Luu, S Gururangan, ... The lancet oncology 17 (4), 484-495, 2016 | 356 | 2016 |
Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas AM Fontebasso, J Schwartzentruber, DA Khuong-Quang, XY Liu, D Sturm, ... Acta neuropathologica 125, 659-669, 2013 | 329 | 2013 |
MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism P Bandopadhayay, LA Ramkissoon, P Jain, G Bergthold, J Wala, R Zeid, ... Nature genetics 48 (3), 273-282, 2016 | 272 | 2016 |
Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors D Faury, A Nantel, SE Dunn, MC Guiot, T Haque, P Hauser, M Garami, ... Journal of Clinical Oncology 25 (10), 1196-1208, 2007 | 272 | 2007 |
Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ... Cancer cell 30 (6), 891-908, 2016 | 224 | 2016 |
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR CL Kleinman, N Gerges, S Papillon-Cavanagh, P Sin-Chan, ... Nature genetics 46 (1), 39-44, 2014 | 217 | 2014 |
Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours K Jacob, S Albrecht, C Sollier, D Faury, E Sader, A Montpetit, D Serre, ... British journal of cancer 101 (4), 722-733, 2009 | 203 | 2009 |
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma M Remke, V Ramaswamy, J Peacock, DJH Shih, C Koelsche, ... Acta neuropathologica 126, 917-929, 2013 | 199 | 2013 |
Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis V Ramaswamy, T Hielscher, SC Mack, A Lassaletta, T Lin, KW Pajtler, ... Journal of Clinical Oncology 34 (21), 2468, 2016 | 188 | 2016 |
Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis J Torchia, D Picard, L Lafay-Cousin, CE Hawkins, SK Kim, L Letourneau, ... The lancet oncology 16 (5), 569-582, 2015 | 181 | 2015 |
The circadian clock controls the expression pattern of the circadian input photoreceptor, phytochrome B LK Bognár, A Hall, É Ádám, SC Thain, F Nagy, AJ Millar Proceedings of the National Academy of Sciences 96 (25), 14652-14657, 1999 | 174 | 1999 |
Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas K Jacob, DA Quang-Khuong, DTW Jones, H Witt, S Lambert, S Albrecht, ... Clinical Cancer Research 17 (14), 4650-4660, 2011 | 156 | 2011 |
Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma H Suzuki, SA Kumar, S Shuai, A Diaz-Navarro, A Gutierrez-Fernandez, ... Nature 574 (7780), 707-711, 2019 | 148 | 2019 |
Real time analysis of brain tissue by direct combination of ultrasonic surgical aspiration and sonic spray mass spectrometry KC Schafer, J Balog, T Szaniszló, D Szalay, G Mezey, J Dénes, L Bognár, ... Analytical Chemistry 83 (20), 7729-7735, 2011 | 122 | 2011 |