Identification of candidate disease genes by integrating Gene Ontologies and protein-interaction networks: case study of primary immunodeficiencies C Ortutay, M Vihinen Nucleic acids research 37 (2), 622-628, 2009 | 112 | 2009 |
KinMutBase: a registry of disease‐causing mutations in protein kinase domains C Ortutay, J Väliaho, K Stenberg, M Vihinen Human mutation 25 (5), 435-442, 2005 | 79 | 2005 |
Immunome: a reference set of genes and proteins for systems biology of the human immune system C Ortutay, M Vihinen Cellular immunology 244 (2), 87-89, 2006 | 77 | 2006 |
Carbonic anhydrase related proteins: molecular biology and evolution A Aspatwar, MEE Tolvanen, C Ortutay, S Parkkila Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial …, 2014 | 70 | 2014 |
Carbonic anhydrase related protein VIII and its role in neurodegeneration and cancer A Aspatwar, M EE Tolvanen, C Ortutay, S Parkkila Current pharmaceutical design 16 (29), 3264-3276, 2010 | 62 | 2010 |
Immunome knowledge base (IKB): an integrated service for immunome research C Ortutay, M Vihinen BMC immunology 10, 1-5, 2009 | 54 | 2009 |
Molecular characterization of the immune system: emergence of proteins, processes, and domains C Ortutay, M Siermala, M Vihinen Immunogenetics 59, 333-348, 2007 | 54 | 2007 |
Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish A Aspatwar, MEE Tolvanen, E Jokitalo, M Parikka, C Ortutay, SKE Harjula, ... Human molecular genetics 22 (3), 417-432, 2013 | 50 | 2013 |
Characterization of all possible single‐nucleotide change caused amino acid substitutions in the kinase domain of Bruton tyrosine kinase J Väliaho, I Faisal, C Ortutay, CIE Smith, M Vihinen Human Mutation 36 (6), 638-647, 2015 | 49 | 2015 |
DoOP: Databases of Orthologous Promoters, collections of clusters of orthologous upstream sequences from chordates and plants E Barta, E Sebestyen, TB Palfy, G Toth, CP Ortutay, L Patthy Nucleic acids research 33 (suppl_1), D86-D90, 2005 | 46 | 2005 |
Bioinformatic analysis of beta carbonic anhydrase sequences from protozoans and metazoans R Zolfaghari Emameh, H Barker, MEE Tolvanen, C Ortutay, S Parkkila Parasites & vectors 7, 1-12, 2014 | 44 | 2014 |
Systematic classification of primary immunodeficiencies based on clinical, pathological, and laboratory parameters C Samarghitean, C Ortutay, M Vihinen The Journal of Immunology 183 (11), 7569-7575, 2009 | 38 | 2009 |
Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML E O’Reilly, SPS Dhami, DV Baev, C Ortutay, A Halpin-McCormick, ... Scientific Reports 8 (1), 15752, 2018 | 36 | 2018 |
Phylogeny of Tec family kinases: identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5 C Ortutay, BF Nore, M Vihinen, CIE Smith Advances in genetics 64, 51-80, 2008 | 34 | 2008 |
Distribution and evolution of short tandem repeats in closely related bacterial genomes E Kassai-Jáger, C Ortutay, G Tóth, T Vellai, Z Gáspári Gene 410 (1), 18-25, 2008 | 33 | 2008 |
Speciation in Chlamydia: Genomewide Phylogenetic Analyses Identified a Reliable Set of Acquired Genes C Ortutay, Z Gaspari, G Toth, E Jager, G Vida, L Orosz, T Vellai Journal of molecular evolution 57, 672-680, 2003 | 27 | 2003 |
ImmTree: database of evolutionary relationships of genes and proteins in the human immune system C Ortutay, M Siermala, M Vihinen Immunome Research 3, 1-6, 2007 | 26 | 2007 |
PseudoGeneQuest–Service for identification of different pseudogene types in the human genome C Ortutay, M Vihinen BMC bioinformatics 9, 1-6, 2008 | 23 | 2008 |
Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in Zebrafish A Aspatwar, MEE Tolvanen, MJT Ojanen, HR Barker, AK Saralahti, ... PLoS One 10 (7), e0134263, 2015 | 22 | 2015 |
Analysis of evolution of carbonic anhydrases IV and XV reveals a rich history of gene duplications and a new group of isozymes MEE Tolvanen, C Ortutay, HR Barker, A Aspatwar, M Patrikainen, ... Bioorganic & medicinal chemistry 21 (6), 1503-1510, 2013 | 22 | 2013 |