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Chantal Guillemette
Chantal Guillemette
Professor and Canada Research Chair, Université Laval and CHU de Québec, Québec, Canada
Adresse e-mail validée de crchul.ulaval.ca
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Membrane transporters in drug development
Nature reviews Drug discovery 9 (3), 215-236, 2010
34852010
Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily
PI Mackenzie, KW Bock, B Burchell, C Guillemette, S Ikushiro, T Iyanagi, ...
Pharmacogenetics and genomics 15 (10), 677-685, 2005
9732005
Pharmacogenomics of human UDP-glucuronosyltransferase enzymes
C Guillemette
The pharmacogenomics journal 3 (3), 136-158, 2003
5582003
Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38)
JF Gagné, V Montminy, P Belanger, K Journault, G Gaucher, ...
Molecular pharmacology 62 (3), 608-617, 2002
4222002
Glucuronidation and the UDP-glucuronosyltransferases in health and disease
PG Wells, PI Mackenzie, JR Chowdhury, C Guillemette, PA Gregory, ...
Drug metabolism and disposition 32 (3), 281-290, 2004
3202004
Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans
C Guillemette, RC Millikan, B Newman, DE Housman
Cancer research 60 (4), 950-956, 2000
2762000
Direct haplotyping of kilobase-size DNA using carbon nanotube probes
AT Woolley, C Guillemette, C Li Cheung, DE Housman, CM Lieber
Nature biotechnology 18 (7), 760-763, 2000
2632000
The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants
O Bernard, C Guillemette
Drug Metabolism and Disposition 32 (8), 775-778, 2004
2512004
Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho …
J Lépine, O Bernard, M Plante, B Têtu, G Pelletier, F Labrie, A Bélanger, ...
The journal of clinical endocrinology & metabolism 89 (10), 5222-5232, 2004
2432004
Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10 …
L Villeneuve, H Girard, LC Fortier, JF Gagné, C Guillemette
Journal of Pharmacology and Experimental Therapeutics 307 (1), 117-128, 2003
2342003
Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene
C Guillemette, JK Ritter, DJ Auyeung, FK Kessler, DE Housman
Pharmacogenetics and Genomics 10 (7), 629-644, 2000
2212000
The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers
E Levesque, R Delage, MO Benoit‐Biancamano, P Caron, O Bernard, ...
Clinical Pharmacology & Therapeutics 81 (3), 392-400, 2007
2022007
Tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk
Z Zheng, JY Park, C Guillemette, SP Schantz, P Lazarus
Journal of the National Cancer Institute 93 (18), 1411-1418, 2001
1992001
Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver
H Girard, O Bernard, LC Fortier, L Villeneuve, Q Hao, DJ Greenblatt, ...
Pharmacogenetics and Genomics 14 (8), 501-515, 2004
1942004
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes
S Ogawa, J Surapisitchat, C Virtanen, M Ogawa, M Niapour, KS Sugamori, ...
Development 140 (15), 3285-3296, 2013
1882013
UGT genomic diversity: beyond gene duplication
C Guillemette, E Lévesque, M Harvey, J Bellemare, V Menard
Drug metabolism reviews 42 (1), 24-44, 2010
1862010
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing
RS Gammal, MH Court, CE Haidar, OF Iwuchukwu, AH Gaur, M Alvarellos, ...
Clinical Pharmacology & Therapeutics 99 (4), 363-369, 2016
1812016
The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor α and γ target gene
O Barbier, L Villeneuve, V Bocher, C Fontaine, IP Torra, C Duhem, ...
Journal of Biological Chemistry 278 (16), 13975-13983, 2003
1772003
Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine
AS Bélanger, P Caron, M Harvey, PA Zimmerman, RK Mehlotra, ...
Drug Metabolism and Disposition 37 (9), 1793-1796, 2009
1762009
Pharmacogenomics of human uridine diphospho‐glucuronosyltransferases and clinical implications
C Guillemette, É Lévesque, M Rouleau
Clinical Pharmacology & Therapeutics 96 (3), 324-339, 2014
1722014
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