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Julio Saez Rodriguez
Julio Saez Rodriguez
Heidelberg University
Adresse e-mail validée de bioquant.uni-heidelberg.de - Page d'accueil
Titre
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Année
Systematic identification of genomic markers of drug sensitivity in cancer cells
MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ...
Nature 483 (7391), 570-575, 2012
22092012
Prospective derivation of a living organoid biobank of colorectal cancer patients
M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ...
Cell 161 (4), 933-945, 2015
14992015
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
11572016
Structural and functional analysis of cellular networks with CellNetAnalyzer
S Klamt, J Saez-Rodriguez, ED Gilles
BMC systems biology 1 (1), 1-13, 2007
6052007
A community effort to assess and improve drug sensitivity prediction algorithms
JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ...
Nature biotechnology 32 (12), 1202-1212, 2014
6042014
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ...
Nature 568 (7753), 511-516, 2019
5742019
Critical assessment of automated flow cytometry data analysis techniques
N Aghaeepour, G Finak, H Hoos, TR Mosmann, R Brinkman, R Gottardo, ...
Nature methods 10 (3), 228-238, 2013
5702013
The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ...
Cell 182 (3), 685-712. e19, 2020
4972020
A methodology for the structural and functional analysis of signaling and regulatory networks
S Klamt, J Saez-Rodriguez, JA Lindquist, L Simeoni, ED Gilles
BMC bioinformatics 7 (1), 1-26, 2006
4602006
Towards a rigorous assessment of systems biology models: the DREAM3 challenges
RJ Prill, D Marbach, J Saez-Rodriguez, PK Sorger, LG Alexopoulos, ...
PloS one 5 (2), e9202, 2010
4472010
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia
K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ...
Cell reports 17 (4), 1193-1205, 2016
4312016
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties
MP Menden, F Iorio, M Garnett, U McDermott, CH Benes, PJ Ballester, ...
PLoS one 8 (4), e61318, 2013
4112013
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
3782016
Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction
J Saez‐Rodriguez, LG Alexopoulos, J Epperlein, R Samaga, ...
Molecular systems biology 5 (1), 331, 2009
3652009
A logical model provides insights into T cell receptor signaling
J Saez-Rodriguez, L Simeoni, JA Lindquist, R Hemenway, U Bommhardt, ...
PLoS computational biology 3 (8), e163, 2007
3602007
Logic-based models for the analysis of cell signaling networks
MK Morris, J Saez-Rodriguez, PK Sorger, DA Lauffenburger
Biochemistry 49 (15), 3216-3224, 2010
3552010
Evaluation of methods for modeling transcription factor sequence specificity
MT Weirauch, A Cote, R Norel, M Annala, Y Zhao, TR Riley, ...
Nature biotechnology 31 (2), 126-134, 2013
3382013
OmniPath: guidelines and gateway for literature-curated signaling pathway resources
D Türei, T Korcsmáros, J Saez-Rodriguez
Nature methods 13 (12), 966-967, 2016
2652016
Pharmacogenomic agreement between two cancer cell line data sets
CCLE Consortium, GDSC Consortium
Nature 528 (7580), 84-87, 2015
261*2015
Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling
DM Wittmann, J Krumsiek, J Saez-Rodriguez, DA Lauffenburger, S Klamt, ...
BMC systems biology 3 (1), 1-21, 2009
2402009
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