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Jefferson Henrich Amaral
Jefferson Henrich Amaral
FMRP USP
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Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension
MF Montenegro, JH Amaral, LC Pinheiro, EK Sakamoto, GC Ferreira, ...
Free Radical Biology and Medicine 51 (1), 144-152, 2011
1492011
Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension
LC Pinheiro, JH Amaral, GC Ferreira, RL Portella, CS Ceron, ...
Free Radical Biology and Medicine 87, 252-262, 2015
942015
Increase in gastric pH reduces hypotensive effect of oral sodium nitrite in rats
LC Pinheiro, MF Montenegro, JH Amaral, GC Ferreira, AM Oliveira, ...
Free Radical Biology and Medicine 53 (4), 701-709, 2012
892012
The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1
DN Meijles, S Sahoo, I Al Ghouleh, JH Amaral, R Bienes-Martinez, ...
Science signaling 10 (501), eaaj1784, 2017
732017
Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension
JH Amaral, GC Ferreira, LC Pinheiro, MF Montenegro, JE Tanus-Santos
Redox biology 5, 340-346, 2015
662015
Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation
IA Ghouleh, S Sahoo, DN Meijles, JH Amaral, DS de Jesus, J Sembrat, ...
Clinical Science 131 (15), 2019-2035, 2017
522017
Antihypertensive and antioxidant effects of a single daily dose of sodium nitrite in a model of renovascular hypertension
MF Montenegro, LC Pinheiro, JH Amaral, DMO Marçal, ACT Palei, ...
Naunyn-Schmiedeberg's archives of pharmacology 385, 509-517, 2012
512012
TEMPOL enhances the antihypertensive effects of sodium nitrite by mechanisms facilitating nitrite-derived gastric nitric oxide formation
JH Amaral, MF Montenegro, LC Pinheiro, GC Ferreira, RP Barroso, ...
Free Radical Biology and Medicine 65, 446-455, 2013
492013
Vascular xanthine oxidoreductase contributes to the antihypertensive effects of sodium nitrite in l-NAME hypertension
MF Montenegro, LC Pinheiro, JH Amaral, GC Ferreira, RL Portella, ...
Naunyn-Schmiedeberg's archives of pharmacology 387, 591-598, 2014
462014
The relationship between blood and serum lead levels in peripartum women and their respective umbilical cords
JH Amaral, VB Rezende, SM Quintana, RF Gerlach, F Barbosa Jr, ...
Basic & clinical pharmacology & toxicology 107 (6), 971-975, 2010
452010
Antioxidant and antihypertensive responses to oral nitrite involves activation of the Nrf2 pathway
JH Amaral, ES Rizzi, R Alves-Lopes, LC Pinheiro, RC Tostes, ...
Free Radical Biology and Medicine 141, 261-268, 2019
382019
Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect
LC Pinheiro, GC Ferreira, JH Amaral, RL Portella, S de OC Tella, ...
Free Radical Biology and Medicine 101, 226-235, 2016
372016
Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype
I Al Ghouleh, DN Meijles, S Mutchler, Q Zhang, S Sahoo, A Gorelova, ...
Proceedings of the National Academy of Sciences 113 (36), E5308-E5317, 2016
352016
Hydrogen peroxide modulates phenylephrine-induced contractile response in renal hypertensive rat aorta
BR Silva, L Pernomian, MD Grando, JH Amaral, JE Tanus-Santos, ...
European journal of pharmacology 721 (1-3), 193-200, 2013
322013
Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects
E Rizzi, JH Amaral, DA Guimaraes, SO Conde-Tella, LC Pinheiro, ...
Free Radical Biology and Medicine 130, 234-243, 2019
302019
Nitrite exerts antioxidant effects, inhibits the mTOR pathway and reverses hypertension-induced cardiac hypertrophy
DA Guimaraes, MA Dos Passos, E Rizzi, LC Pinheiro, JH Amaral, ...
Free Radical Biology and Medicine 120, 25-32, 2018
302018
Analytical method for determination of nitric oxide in zebrafish larvae: toxicological and pharmacological applications
CE Leite, A da Cruz Teixeira, FF Cruz, SC Concatto, JH Amaral, ...
Analytical biochemistry 421 (2), 534-540, 2012
272012
Should we measure serum or plasma lead concentrations?
VB Rezende, JH Amaral, RF Gerlach, F Barbosa Jr, JE Tanus-Santos
Journal of Trace Elements in Medicine and Biology 24 (3), 147-151, 2010
262010
The antihypertensive effects of sodium nitrite are not associated with circulating angiotensin converting enzyme inhibition
LC Pinheiro, JH Amaral, GC Ferreira, MF Montenegro, GH Oliveira-Paula, ...
Nitric Oxide 40, 52-59, 2014
242014
Vitamin D receptor haplotypes affect lead levels during pregnancy
VB Rezende, JH Amaral, SM Quintana, RF Gerlach, F Barbosa Jr, ...
Science of the total environment 408 (21), 4955-4960, 2010
222010
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