Promoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening V Kloten, B Becker, K Winner, MG Schrauder, PA Fasching, T Anzeneder, ... Breast Cancer Research 15, 1-11, 2013 | 169 | 2013 |
Multicenter evaluation of circulating cell-free DNA extraction and downstream analyses for the development of standardized (pre) analytical work flows R Lampignano, MHD Neumann, S Weber, V Kloten, A Herdean, T Voss, ... Clinical chemistry 66 (1), 149-160, 2020 | 117 | 2020 |
Circulating tumor cell PD-L1 expression as biomarker for therapeutic efficacy of immune checkpoint inhibition in NSCLC V Kloten, R Lampignano, T Krahn, T Schlange Cells 8 (8), 809, 2019 | 90 | 2019 |
Liquid biopsy in colon cancer: comparison of different circulating DNA extraction systems following absolute quantification of KRAS mutations using Intplex allele-specific PCR V Kloten, N Rüchel, NO Brüchle, J Gasthaus, N Freudenmacher, F Steib, ... Oncotarget 8 (49), 86253, 2017 | 72 | 2017 |
Technical evaluation of commercial mutation analysis platforms and reference materials for liquid biopsy profiling S Weber, B Spiegl, SO Perakis, CM Ulz, PM Abuja, K Kashofer, ... Cancers 12 (6), 1588, 2020 | 49 | 2020 |
Multicenter evaluation of circulating plasma microRNA extraction technologies for the development of clinically feasible reverse transcription quantitative PCR and next … V Kloten, MHD Neumann, F Di Pasquale, M Sprenger-Haussels, ... Clinical Chemistry 65 (9), 1132-1140, 2019 | 45 | 2019 |
ITIH5 mediates epigenetic reprogramming of breast cancer cells M Rose, V Kloten, E Noetzel, L Gola, J Ehling, T Heide, SK Meurer, ... Molecular cancer 16, 1-22, 2017 | 40 | 2017 |
Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients M Schlensog, L Magnus, T Heide, J Eschenbruch, F Steib, M Tator, ... Epigenetics 13 (3), 214-227, 2018 | 38 | 2018 |
Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator … V Kloten, M Rose, S Kaspar, S von Stillfried, R Knüchel, E Dahl Epigenetics 9 (9), 1290-1301, 2014 | 37 | 2014 |
Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcome MM Doetsch, V Kloten, M Schlensog, T Heide, T Braunschweig, J Veeck, ... Epigenetics 10 (10), 903-912, 2015 | 36 | 2015 |
Integrating circulating miRNA analysis in the clinical management of lung cancer: Present or future? R Lampignano, V Kloten, T Krahn, T Schlange Molecular Aspects of Medicine 72, 100844, 2020 | 29 | 2020 |
ITIH5 induces a shift in TGF‐β superfamily signaling involving endoglin and reduces risk for breast cancer metastasis and tumor death M Rose, SK Meurer, V Kloten, R Weiskirchen, B Denecke, ... Molecular carcinogenesis 57 (2), 167-181, 2018 | 29 | 2018 |
SNiPER: A novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection J Mijnes, J Tiedemann, J Eschenbruch, J Gasthaus, S Bringezu, ... Oncotarget 10 (60), 6494, 2019 | 20 | 2019 |
Gene expression analysis combined with functional genomics approach identifies ITIH5 as tumor suppressor gene in cervical carcinogenesis J Dittmann, A Ziegfeld, L Jansen, M Gajda, V Kloten, E Dahl, ... Molecular Carcinogenesis 56 (6), 1578-1589, 2017 | 18 | 2017 |
Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients’ Outcome in Basal-Like Breast Cancer V Kloten, M Schlensog, J Eschenbruch, J Gasthaus, J Tiedemann, ... PLoS One 11 (7), e0159073, 2016 | 15 | 2016 |
Multicenter evaluation of independent high-throughput and RT-qPCR technologies for the development of analytical workflows for circulating miRNA analysis A Babayan, MHD Neumann, A Herdean, JM Shaffer, M Janning, F Kobus, ... Cancers 12 (5), 1166, 2020 | 11 | 2020 |
Liquid biopsy analysis using cell-free DNA (cfDNA) Opportunities and limitations E Dahl, V Kloten Der Pathologe 36, 572-578, 2015 | 4 | 2015 |
Correction: SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection J Mijnes, J Tiedemann, J Eschenbruch, J Gasthaus, S Bringezu, ... Oncotarget 11 (30), 2958, 2020 | 3 | 2020 |
Liquid-biopsy-Analysen mithilfe zellfreier DNA (cfDNA) E Dahl, V Kloten Der Pathologe 6 (36), 572-578, 2015 | 3 | 2015 |
Liquid biopsy in human non-small-cell lung cancer: Blood-based analysis of ctDNA methylation H Schulz, M Tator, J Spillner, M Dreher, R Knüchel-Clarke, V Kloten, ... Der Pathologe 39, 193-198, 2018 | 2 | 2018 |