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| Molecular biomarkers of Alzheimer's disease: progress and prospects T Lashley, JM Schott, P Weston, CE Murray, H Wellington, A Keshavan, ... Disease models & mechanisms 11 (5), dmm031781, 2018 | 212 | 2018 |
| The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 207 | 2019 |
| G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 207 | 2018 |
| Modified ketogenic diet is associated with improved cerebrospinal fluid biomarker profile, cerebral perfusion, and cerebral ketone body uptake in older adults at risk for … BJ Neth, A Mintz, C Whitlow, Y Jung, KS Sai, TC Register, D Kellar, ... Neurobiology of aging 86, 54-63, 2020 | 165 | 2020 |
| Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay WE Heywood, D Galimberti, E Bliss, E Sirka, RW Paterson, ... Molecular neurodegeneration 10, 1-16, 2015 | 159 | 2015 |
| Evaluation of mutant huntingtin and neurofilament proteins as potential markers in Huntington’s disease LM Byrne, FB Rodrigues, EB Johnson, PA Wijeratne, E De Vita, ... Science translational medicine 10 (458), eaat7108, 2018 | 149 | 2018 |
| Human induced pluripotent stem cell-derived microglia-like cells harboring TREM2 missense mutations show specific deficits in phagocytosis P Garcia-Reitboeck, A Phillips, TM Piers, C Villegas-Llerena, M Butler, ... Cell Reports 24 (9), 2300-2311, 2018 | 141 | 2018 |
| Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia C Heller, MS Foiani, K Moore, R Convery, M Bocchetta, M Neason, ... Journal of Neurology, Neurosurgery & Psychiatry 91 (3), 263-270, 2020 | 133 | 2020 |
| Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta C Arber, J Toombs, C Lovejoy, NS Ryan, RW Paterson, N Willumsen, ... Molecular Psychiatry 25 (11), 2919-2931, 2020 | 127 | 2020 |
| Diagnosis across the spectrum of progressive supranuclear palsy and corticobasal syndrome E Jabbari, N Holland, V Chelban, PS Jones, R Lamb, C Rawlinson, T Guo, ... JAMA neurology 77 (3), 377-387, 2020 | 123 | 2020 |
| Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase N Stahmann, A Woods, K Spengler, A Heslegrave, R Bauer, S Krause, ... Journal of biological chemistry 285 (14), 10638-10652, 2010 | 118 | 2010 |
| Population-based blood screening for preclinical Alzheimer’s disease in a British birth cohort at age 70 A Keshavan, J Pannee, TK Karikari, JL Rodriguez, NJ Ashton, ... Brain 144 (2), 434-449, 2021 | 107 | 2021 |
| Cerebrospinal fluid in the differential diagnosis of Alzheimer’s disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic RW Paterson, CF Slattery, T Poole, JM Nicholas, NK Magdalinou, ... Alzheimer's research & therapy 10, 1-11, 2018 | 105 | 2018 |
| Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer’s disease: a longitudinal cohort study A O’Connor, TK Karikari, T Poole, NJ Ashton, J Lantero Rodriguez, ... Molecular psychiatry 26 (10), 5967-5976, 2021 | 93 | 2021 |
| Soluble TREM-2 in cerebrospinal fluid from patients with multiple sclerosis treated with natalizumab or mitoxantrone A Öhrfelt, M Axelsson, C Malmeström, L Novakova, A Heslegrave, ... Multiple Sclerosis Journal 22 (12), 1587-1595, 2016 | 93 | 2016 |
| Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and … ML Alosco, Y Tripodis, NG Fritts, A Heslegrave, CM Baugh, S Conneely, ... Alzheimer's & Dementia 14 (9), 1159-1170, 2018 | 91 | 2018 |
| Nitric oxide‐dependent damage to neuronal mitochondria involves the NMDA receptor VC Stewart, AJ Heslegrave, GC Brown, JB Clark, SJR Heales European Journal of Neuroscience 15 (3), 458-464, 2002 | 90 | 2002 |
| Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury NSN Graham, KA Zimmerman, F Moro, A Heslegrave, SA Maillard, ... Science translational medicine 13 (613), eabg9922, 2021 | 88 | 2021 |
| Laboratory biomarkers associated with COVID-19 severity and management S Keddie, O Ziff, MKL Chou, RL Taylor, A Heslegrave, E Garr, ... Clinical immunology 221, 108614, 2020 | 86 | 2020 |
Henrik ZetterbergSahlgrenskaVerified email at clinchem.gu.se
