Differential β-Arrestin–Dependent Conformational Signaling and Cellular Responses Revealed by Angiotensin Analogs B Zimmerman, A Beautrait, B Aguila, R Charles, E Escher, A Claing, ... Science signaling 5 (221), ra33-ra33, 2012 | 168 | 2012 |
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling A Beautrait, JS Paradis, B Zimmerman, J Giubilaro, L Nikolajev, ... Nature Communications 8, 15054, 2017 | 142 | 2017 |
Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression JS Paradis, S Ly, É Blondel-Tepaz, JA Galan, A Beautrait, MGH Scott, ... Proceedings of the National Academy of Sciences 112 (37), E5160-E5168, 2015 | 53 | 2015 |
Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2 INSIGHTS FROM INTACT CELL PHOSPHORYLATION AND RECRUITMENT ASSAYS A Beautrait, KR Michalski, TS Lopez, KM Mannix, DJ McDonald, ... Journal of Biological Chemistry 289 (36), 25262-25275, 2014 | 49 | 2014 |
Emerging paradigm of intracellular targeting of G protein-coupled receptors M Chaturvedi, J Schilling, A Beautrait, M Bouvier, JL Benovic, AK Shukla Trends in biochemical sciences 43 (7), 533-546, 2018 | 44 | 2018 |
Quantifying biased signaling in GPCRs using BRET-based biosensors Y Namkung, O Radresa, S Armando, D Devost, A Beautrait, C Le Gouill, ... Methods 92, 5-10, 2016 | 44 | 2016 |
Enhancing Hit Discovery in Virtual Screening through Absolute Protein–Ligand Binding Free-Energy Calculations W Chen, D Cui, SV Jerome, M Michino, EB Lenselink, DJ Huggins, ... Journal of Chemical Information and Modeling, 2023 | 30 | 2023 |
SHEF: a vHTS geometrical filter using coefficients of spherical harmonic molecular surfaces W Cai, J Xu, X Shao, V Leroux, A Beautrait, B Maigret Journal of molecular modeling 14 (5), 393-401, 2008 | 25 | 2008 |
Multiple-step virtual screening using VSM-G: overview and validation of fast geometrical matching enrichment A Beautrait, V Leroux, M Chavent, L Ghemtio, MD Devignes, ... Journal of molecular modeling 14 (2), 135-148, 2008 | 25 | 2008 |
A fast surface-matching procedure for protein–ligand docking MEB Yamagishi, NF Martins, G Neshich, W Cai, X Shao, A Beautrait, ... Journal of Molecular Modeling 12 (6), 965-972, 2006 | 20 | 2006 |
Identification of allosteric inhibitors against active caspase-6 A Tubeleviciute-Aydin, A Beautrait, J Lynham, G Sharma, A Gorelik, ... Scientific reports 9 (1), 1-19, 2019 | 19 | 2019 |
Identification of Polo-like kinase 1 interaction inhibitors using a novel cell-based assay K Normandin, JF Lavallée, M Futter, A Beautrait, J Duchaine, S Guiral, ... Scientific reports 6 (1), 1-20, 2016 | 18 | 2016 |
Induced-Fit Docking Enables Accurate Free Energy Perturbation Calculations in Homology Models T Xu, K Zhu, A Beautrait, J Vendome, KW Borrelli, R Abel, RA Friesner, ... Journal of Chemical Theory and Computation, 2022 | 11 | 2022 |
Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen J Giubilaro, DA Schuetz, TM Stepniewski, Y Namkung, E Khoury, ... Nature Communications 12 (1), 1-16, 2021 | 8 | 2021 |
Beta-arrestins operate an on/off control switch for focal adhesion kinase activity RA Alexander, I Lot, K Saha, G Abadie, M Lambert, E Decosta, ... Cellular and Molecular Life Sciences, 1-21, 2020 | 8 | 2020 |
Induced fit in liver X receptor beta: A molecular dynamics‐based investigation A Beautrait, AS Karaboga, M Souchet, B Maigret Proteins: Structure, Function, and Bioinformatics 72 (3), 873-882, 2008 | 8 | 2008 |
Développement et validation de la plateforme de criblage virtuel VSM-G et étude du domaine FAT de la kinase d'adhérence focale FAK A Beautrait Université Henri Poincaré-Nancy I, 2008 | 7 | 2008 |
Arrestin biosensor M Bouvier, PG Charest, C LeGouill, A Beautrait, SA Laporte, ... US Patent 8,883,486, 2014 | 5 | 2014 |
Do natural silks make good engineering materials? NA Morrison, FI Bell, A Beautrait, J Ritchie, C Smith, IJ McEwen, C Viney MRS Online Proceedings Library (OPL) 823, 2004 | 4 | 2004 |
Shape-Based Virtual Screening of a Billion-Compound Library Identifies Mycobacterial Lipoamide Dehydrogenase Inhibitors M Michino, A Beautrait, NA Boyles, A Nadupalli, A Dementiev, S Sun, ... ACS Bio & Med Chem Au, 2023 | | 2023 |