Wen Hwa Lee
Wen Hwa Lee
Action Against AMD, SGC and University of Oxford
Adresse e-mail validée de actionagainstamd.org - Page d'accueil
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Large-scale structural analysis of the classical human protein tyrosine phosphatome
AJ Barr, E Ugochukwu, WH Lee, ONF King, P Filippakopoulos, I Alfano, ...
Cell 136 (2), 352-363, 2009
4072009
Structural basis for protein–protein interactions in the 14-3-3 protein family
X Yang, WH Lee, F Sobott, E Papagrigoriou, CV Robinson, ...
Proceedings of the National Academy of Sciences 103 (46), 17237-17242, 2006
2892006
Structure of the CaMKIIδ/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation
P Rellos, ACW Pike, FH Niesen, E Salah, WH Lee, F Von Delft, S Knapp
PLoS Biol 8 (7), e1000426, 2010
1932010
Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases
TL Davis, JR Walker, V Campagna-Slater, PJ Finerty Jr, R Paramanathan, ...
PLoS Biol 8 (7), e1000439, 2010
1812010
Fast structure-based virtual ligand screening combining FRED, DOCK, and Surflex
MA Miteva, WH Lee, MO Montes, BO Villoutreix
Journal of medicinal chemistry 48 (19), 6012-6022, 2005
1302005
Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs
J Eswaran, WH Lee, JÉ Debreczeni, P Filippakopoulos, A Turnbull, ...
Structure 15 (2), 201-213, 2007
1172007
Reduced phosphatase activity of SHP‐2 in LEOPARD syndrome: Consequences for PI3K binding on Gab1
N Hanna, A Montagner, WH Lee, M Miteva, M Vidal, M Vidaud, B Parfait, ...
FEBS letters 580 (10), 2477-2482, 2006
1102006
Comparative structural analysis of lipid binding START domains
AG Thorsell, WH Lee, C Persson, MI Siponen, M Nilsson, RD Busam, ...
Plos one 6 (6), e19521, 2011
1012011
Structural Basis for Low Catalytic Activity in Lys49 Phospholipases A2A Hypothesis:  The Crystal Structure of Piratoxin II Complexed to Fatty Acid,
WH Lee, MT da Silva Giotto, S Marangoni, MH Toyama, I Polikarpov, ...
Biochemistry 40 (1), 28-36, 2001
952001
Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity
P Lukacik, B Keller, G Bunkoczi, K Kavanagh, W Hwa Lee, J Adamski, ...
Biochemical Journal 402 (3), 419-427, 2007
812007
Novel mutations in ACVR1 result in atypical features in two fibrodysplasia ossificans progressiva patients
KA Petrie, WH Lee, AN Bullock, JJ Pointon, R Smith, RGG Russell, ...
PloS one 4 (3), e5005, 2009
782009
Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor
AN Bullock, S Russo, A Amos, N Pagano, H Bregman, JE Debreczeni, ...
PLoS One 4 (10), e7112, 2009
772009
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins
O Gileadi, S Knapp, WH Lee, BD Marsden, S Müller, FH Niesen, ...
Journal of structural and functional genomics 8 (2-3), 107-119, 2007
702007
Structural basis for substrate specificity in human monomeric carbonyl reductases
ES Pilka, FH Niesen, WH Lee, Y El-Hawari, JE Dunford, G Kochan, ...
PloS one 4 (10), e7113, 2009
592009
Characterization of Human DHRS6, an Orphan Short Chain Dehydrogenase/Reductase Enzyme A NOVEL, CYTOSOLIC TYPE 2 R-β-HYDROXYBUTYRATE DEHYDROGENASE
K Guo, P Lukacik, E Papagrigoriou, M Meier, WH Lee, J Adamski, ...
Journal of Biological Chemistry 281 (15), 10291-10297, 2006
542006
Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases
J Eswaran, JP von Kries, B Marsden, E Longman, JÉ Debreczeni, ...
Biochemical Journal 395 (3), 483-491, 2006
532006
Disseminating structural genomics data to the public: from a data dump to an animated story
R Abagyan, WH Lee, E Raush, L Budagyan, M Totrov, M Sundstrom, ...
Trends in biochemical sciences 31 (2), 76-78, 2006
492006
Structural basis of fumarate hydratase deficiency
S Picaud, KL Kavanagh, WW Yue, WH Lee, S Muller-Knapp, O Gileadi, ...
Journal of inherited metabolic disease 34 (3), 671-676, 2011
462011
Structural comparison of human mammalian ste20-like kinases
CJ Record, A Chaikuad, P Rellos, S Das, ACW Pike, O Fedorov, ...
PloS one 5 (8), e11905, 2010
452010
The Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin and cell surfaces via positively charged amino acids in CCP1–2
L Mark, WH Lee, OB Spiller, BO Villoutreix, AM Blom
Molecular immunology 43 (10), 1665-1675, 2006
452006
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