A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing G Chen, AA Abdeen, Y Wang, PK Shahi, S Robertson, R Xie, M Suzuki, ... Nature nanotechnology 14 (10), 974-980, 2019 | 283 | 2019 |
A pH-responsive silica–metal–organic framework hybrid nanoparticle for the delivery of hydrophilic drugs, nucleic acids, and CRISPR-Cas9 genome-editing machineries Y Wang, PK Shahi, R Xie, H Zhang, AA Abdeen, N Yodsanit, Z Ma, ... Journal of controlled release 324, 194-203, 2020 | 66 | 2020 |
A Novel KCNJ13 Nonsense Mutation and Loss of Kir7.1 Channel Function Causes Leber Congenital Amaurosis (LCA16) BR Pattnaik, PK Shahi, MJ Marino, X Liu, N York, S Brar, J Chiang, ... Human mutation 36 (7), 720-727, 2015 | 60 | 2015 |
The possible roles of hyperpolarization-activated cyclic nucleotide channels in regulating pacemaker activity in colonic interstitial cells of Cajal PK Shahi, S Choi, DC Zuo, MY Kim, CG Park, YD Kim, J Lee, KJ Park, I So, ... Journal of gastroenterology 49, 1001-1010, 2014 | 56 | 2014 |
In vivo targeted delivery of nucleic acids and CRISPR genome editors enabled by GSH-responsive silica nanoparticles Y Wang, PK Shahi, X Wang, R Xie, Y Zhao, M Wu, S Roge, BR Pattnaik, ... Journal of Controlled Release 336, 296-309, 2021 | 45 | 2021 |
Human iPSC modeling reveals mutation-specific responses to gene therapy in a genotypically diverse dominant maculopathy D Sinha, B Steyer, PK Shahi, KP Mueller, R Valiauga, KL Edwards, ... The American Journal of Human Genetics 107 (2), 278-292, 2020 | 39 | 2020 |
Abnormal electroretinogram after Kir7. 1 channel suppression suggests role in retinal electrophysiology PK Shahi, X Liu, B Aul, A Moyer, A Pattnaik, J Denton, DAM Pillers, ... Scientific Reports 7 (1), 10651, 2017 | 39 | 2017 |
Gene augmentation and readthrough rescue channelopathy in an iPSC-RPE model of congenital blindness PK Shahi, D Hermans, D Sinha, S Brar, H Moulton, S Stulo, KD Borys, ... The American Journal of Human Genetics 104 (2), 310-318, 2019 | 36 | 2019 |
Role of the sigma-1 receptor chaperone in rod and cone photoreceptor degenerations in a mouse model of retinitis pigmentosa H Yang, Y Fu, X Liu, PK Shahi, TA Mavlyutov, J Li, A Yao, SZW Guo, ... Molecular neurodegeneration 12, 1-15, 2017 | 36 | 2017 |
Inhibition of pacemaker activity in interstitial cells of Cajal by LPS via NF-κB and MAP kinase DC Zuo, S Choi, PK Shahi, MY Kim, CG Park, YD Kim, J Lee, IY Chang, ... World Journal of Gastroenterology: WJG 19 (8), 1210, 2013 | 31 | 2013 |
5-hydroxytryptamine generates tonic inward currents on pacemaker activity of interstitial cells of cajal from mouse small intestine PK Shahi, S Choi, DC Zuo, CH Yeum, PJ Yoon, J Lee, YD Kim, CG Park, ... The Korean Journal of Physiology & Pharmacology: Official Journal of the …, 2011 | 26 | 2011 |
Interplay of hydrogen sulfide and nitric oxide on the pacemaker activity of interstitial cells of cajal from mouse small intestine PJ Yoon, SP Parajuli, DC Zuo, PK Shahi, HJ Oh, HR Shin, MJ Lee, ... Chonnam medical journal 47 (2), 72, 2011 | 25 | 2011 |
Novel anti-angiogenic PEDF-derived small peptides mitigate choroidal neovascularization N Sheibani, S Wang, SR Darjatmoko, DL Fisk, PK Shahi, BR Pattnaik, ... Experimental eye research 188, 107798, 2019 | 24 | 2019 |
Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration L Zhao, J Li, Y Fu, M Zhang, B Wang, J Ouellette, PK Shahi, BR Pattnaik, ... Journal of neuroinflammation 14, 1-15, 2017 | 22 | 2017 |
Neurotensin modulates pacemaker activity in interstitial cells of Cajal from the mouse small intestine J Lee, YD Kim, CG Park, MY Kim, IY Chang, DC Zuo, PK Shahi, S Choi, ... Molecules and cells 33, 509-516, 2012 | 16 | 2012 |
Kir7.1 disease mutant T153I within the inner pore affects K+ conduction KM Beverley, PK Shahi, M Kabra, Q Zhao, J Heyrman, J Steffen, ... American Journal of Physiology-Cell Physiology 323 (1), C56-C68, 2022 | 15 | 2022 |
Action of lipopolysaccharide on interstitial cells of cajal from mouse small intestine DC Zuo, S Choi, PK Shahi, MY Kim, CG Park, YD Kim, J Lee, IY Chang, ... Pharmacology 90 (3-4), 151-159, 2012 | 14 | 2012 |
Modulation of Tmem135 leads to retinal pigmented epithelium pathologies in mice M Landowski, S Grindel, PK Shahi, A Johnson, D Western, A Race, F Shi, ... Investigative Ophthalmology & Visual Science 61 (12), 16-16, 2020 | 10 | 2020 |
Basal cGMP regulates the resting pacemaker potential frequency of cultured mouse colonic interstitial cells of Cajal PK Shahi, S Choi, YJ Jeong, CG Park, I So, JY Jun Naunyn-Schmiedeberg's archives of pharmacology 387, 641-648, 2014 | 10 | 2014 |
Capsaicin inhibits the spontaneous pacemaker activity in interstitial cells of Cajal from the small intestine of mouse S Choi, JM Sun, PK Shahi, DC Zuo, HI Kim, JY Jun Journal of Neurogastroenterology and Motility 16 (3), 265, 2010 | 10 | 2010 |