| Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles RB Best, X Zhu, J Shim, PEM Lopes, J Mittal, M Feig, AD MacKerell Jr Journal of chemical theory and computation 8 (9), 3257-3273, 2012 | 4044 | 2012 |
| ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain AE Conicella, GH Zerze, J Mittal, NL Fawzi Structure 24 (9), 1537-1549, 2016 | 711 | 2016 |
| Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association RB Best, W Zheng, J Mittal Journal of chemical theory and computation 10 (11), 5113-5124, 2014 | 618 | 2014 |
| Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ... The EMBO journal 36 (20), 2951-2967, 2017 | 579 | 2017 |
| Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi Nature Structural & Molecular Biology 26 (7), 637, 2019 | 482 | 2019 |
| Sequence determinants of protein phase behavior from a coarse-grained model GL Dignon, W Zheng, YC Kim, RB Best, J Mittal PLoS computational biology 14 (1), e1005941, 2018 | 413 | 2018 |
| Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties GL Dignon, RB Best, J Mittal Annual Review of Physical Chemistry 71, 53-75, 2020 | 373 | 2020 |
| Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ... Molecular cell 69 (3), 465-479. e7, 2018 | 338 | 2018 |
| Protein simulations with an optimized water model: cooperative helix formation and temperature-induced unfolded state collapse RB Best, J Mittal The Journal of Physical Chemistry B 114 (46), 14916-14923, 2010 | 277 | 2010 |
| Relation between single-molecule properties and phase behavior of intrinsically disordered proteins GL Dignon, W Zheng, RB Best, YC Kim, J Mittal Proceedings of the National Academy of Sciences 115 (40), 9929-9934, 2018 | 271 | 2018 |
| TDP-43 α-helical structure tunes liquid–liquid phase separation and function AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D’Ordine, YC Kim, ... Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020 | 268 | 2020 |
| Temperature-controlled liquid–liquid phase separation of disordered proteins GL Dignon, W Zheng, YC Kim, J Mittal ACS central science 5 (5), 821-830, 2019 | 203 | 2019 |
| Layering and position-dependent diffusive dynamics of confined fluids J Mittal, TM Truskett, JR Errington, G Hummer Physical review letters 100 (14), 145901, 2008 | 202 | 2008 |
| Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior BS Schuster, GL Dignon, WS Tang, FM Kelley, AK Ranganath, ... Proceedings of the National Academy of Sciences 117 (21), 11421-11431, 2020 | 193 | 2020 |
| Excess-entropy-based anomalies for a waterlike fluid JR Errington, TM Truskett, J Mittal The Journal of chemical physics 125 (24), 2006 | 189 | 2006 |
| A carbon nanotube reporter of microRNA hybridization events in vivo JD Harvey, PV Jena, HA Baker, GH Zerze, RM Williams, TV Galassi, ... Nature Biomedical Engineering 1, 0041, 2017 | 188 | 2017 |
| Temperature-dependent solvation modulates the dimensions of disordered proteins R Wuttke, H Hofmann, D Nettels, MB Borgia, J Mittal, RB Best, B Schuler Proceedings of the National Academy of Sciences 111 (14), 5213-5218, 2014 | 186 | 2014 |
| Thermodynamics and kinetics of protein folding under confinement J Mittal, RB Best Proceedings of the National Academy of Sciences 105 (51), 20233-20238, 2008 | 181 | 2008 |
| Thermodynamics predicts how confinement modifies the dynamics of the equilibrium hard-sphere fluid J Mittal, JR Errington, TM Truskett Physical review letters 96 (17), 177804, 2006 | 165 | 2006 |
| Static and dynamic correlations in water at hydrophobic interfaces J Mittal, G Hummer Proceedings of the National Academy of Sciences 105 (51), 20130-20135, 2008 | 157 | 2008 |
Robert BestSenior Investigator, National Institutes of HealthVerified email at helix.nih.gov
