| A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy WWL Choi, DD Weisenburger, TC Greiner, MA Piris, AH Banham, ... Clinical cancer research 15 (17), 5494-5502, 2009 | 728 | 2009 |
| Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma J Iqbal, DD Weisenburger, TC Greiner, JM Vose, T McKeithan, C Kucuk, ... Blood 115 (5), 1026-1036, 2010 | 345 | 2010 |
| EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis I Velichutina, R Shaknovich, H Geng, NA Johnson, RD Gascoyne, ... Blood, The Journal of the American Society of Hematology 116 (24), 5247-5255, 2010 | 288 | 2010 |
| BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ... Nature 473 (7347), 384-388, 2011 | 190 | 2011 |
| Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies J Iqbal, C Kucuk, RJ Deleeuw, G Srivastava, W Tam, H Geng, D Klinkebiel, ... Leukemia 23 (6), 1139-1151, 2009 | 186 | 2009 |
| TET1 is a tumor suppressor of hematopoietic malignancy L Cimmino, MM Dawlaty, D Ndiaye-Lobry, YS Yap, S Bakogianni, Y Yu, ... Nature immunology 16 (6), 653-662, 2015 | 157 | 2015 |
| Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia S Swaminathan, L Klemm, E Park, E Papaemmanuil, A Ford, SM Kweon, ... Nature immunology 16 (7), 766-774, 2015 | 146 | 2015 |
| CREBBP inactivation promotes the development of HDAC3-dependent lymphomas Y Jiang, A Ortega-Molina, H Geng, HY Ying, K Hatzi, S Parsa, D McNally, ... Cancer discovery 7 (1), 38-53, 2017 | 135 | 2017 |
| DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma R Shaknovich, H Geng, NA Johnson, L Tsikitas, L Cerchietti, JM Greally, ... Blood, The Journal of the American Society of Hematology 116 (20), e81-e89, 2010 | 135 | 2010 |
| RUNX1 is a key target in t (4; 11) leukemias that contributes to gene activation through an AF4-MLL complex interaction AC Wilkinson, E Ballabio, H Geng, P North, M Tapia, J Kerry, D Biswas, ... Cell reports 3 (1), 116-127, 2013 | 116 | 2013 |
| Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile K Cramer-Morales, M Nieborowska-Skorska, K Scheibner, M Padget, ... Blood, The Journal of the American Society of Hematology 122 (7), 1293-1304, 2013 | 114 | 2013 |
| Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity S De, R Shaknovich, M Riester, O Elemento, H Geng, M Kormaksson, ... PLoS Genet 9 (1), e1003137, 2013 | 111 | 2013 |
| Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 109 | 2017 |
| Genome wide transcriptional analysis of resting and IL2 activated human natural killer cells: gene expression signatures indicative of novel molecular signaling pathways K Dybkaer, J Iqbal, G Zhou, H Geng, L Xiao, A Schmitz, F d'Amore, ... BMC genomics 8 (1), 1-17, 2007 | 102 | 2007 |
| Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia Z Chen, S Shojaee, M Buchner, H Geng, JW Lee, L Klemm, B Titz, ... Nature 521 (7552), 357-361, 2015 | 96 | 2015 |
| Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy YT Hsieh, EJ Gang, H Geng, E Park, S Huantes, D Chudziak, K Dauber, ... Blood, The Journal of the American Society of Hematology 121 (10), 1814-1818, 2013 | 95 | 2013 |
| MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199 JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, H Geng, I Marzo, ... Cell reports 13 (12), 2715-2727, 2015 | 88 | 2015 |
| Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia H Geng, C Hurtz, KB Lenz, Z Chen, D Baumjohann, S Thompson, ... Cancer cell 27 (3), 409-425, 2015 | 88 | 2015 |
| BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint S Swaminathan, C Huang, H Geng, Z Chen, R Harvey, H Kang, C Ng, ... Nature medicine 19 (8), 1014-1022, 2013 | 88 | 2013 |
| Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma MG Cardenas, W Yu, W Beguelin, MR Teater, H Geng, RL Goldstein, ... The Journal of clinical investigation 126 (9), 3351-3362, 2016 | 83 | 2016 |
Christian HurtzUniversity of PennsylvaniaAdresse e-mail validée de pennmedicine.upenn.edu
