Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer C Isella, F Brundu, SE Bellomo, F Galimi, E Zanella, R Porporato, C Petti, ... Nature communications 8 (1), 15107, 2017 | 268 | 2017 |
The MET Oncogene Is a Functional Marker of a Glioblastoma Stem Cell Subtype F De Bacco, E Casanova, E Medico, S Pellegatta, F Orzan, R Albano, ... Cancer research 72 (17), 4537-4550, 2012 | 162 | 2012 |
MET signaling in colon cancer stem-like cells blunts the therapeutic response to EGFR inhibitors P Luraghi, G Reato, E Cipriano, F Sassi, F Orzan, V Bigatto, F De Bacco, ... Cancer research 74 (6), 1857-1869, 2014 | 150 | 2014 |
Enhancer of Zeste 2 (EZH2) is up‐regulated in malignant gliomas and in glioma stem‐like cells F Orzan, S Pellegatta, PL Poliani, F Pisati, V Caldera, F Menghi, D Kapetis, ... Neuropathology and applied neurobiology 37 (4), 381-394, 2011 | 148 | 2011 |
MET inhibition overcomes radiation resistance of glioblastoma stem‐like cells F De Bacco, A D'Ambrosio, E Casanova, F Orzan, R Neggia, R Albano, ... EMBO molecular medicine 8 (5), 550-568, 2016 | 91 | 2016 |
Mapping of candidate region for chordoma development to 1p36. 13 by LOH analysis P Riva, F Crosti, F Orzan, L Dalprà, P Mortini, A Parafioriti, B Pollo, ... International journal of cancer 107 (3), 493-497, 2003 | 65 | 2003 |
Genetic evolution of glioblastoma stem-like cells from primary to recurrent tumor F Orzan, F De Bacco, G Crisafulli, S Pellegatta, B Mussolin, G Siravegna, ... Stem cells 35 (11), 2218-2228, 2017 | 61 | 2017 |
Evidence for non-homologous end joining and non-allelic homologous recombination in atypical NF1 microdeletions M Venturin, C Gervasini, F Orzan, A Bentivegna, L Corrado, P Colapietro, ... Human genetics 115, 69-80, 2004 | 54 | 2004 |
Evaluation of 1p36 markers and clinical outcome in a skull base chordoma study M Longoni, F Orzan, M Stroppi, N Boari, P Mortini, P Riva Neuro-oncology 10 (1), 52-60, 2008 | 48 | 2008 |
Intra-tumoral dendritic cells increase efficacy of peripheral vaccination by modulation of glioma microenvironment S Pellegatta, PL Poliani, E Stucchi, D Corno, CA Colombo, F Orzan, ... Neuro-oncology 12 (4), 377-388, 2010 | 47 | 2010 |
A molecularly annotated model of patient-derived colon cancer stem–like cells to assess genetic and nongenetic mechanisms of resistance to anti-EGFR therapy P Luraghi, V Bigatto, E Cipriano, G Reato, F Orzan, F Sassi, F De Bacco, ... Clinical Cancer Research 24 (4), 807-820, 2018 | 30 | 2018 |
Expression study of the target receptor tyrosine kinase of Imatinib mesylate in skull base chordomas F Orzan, MR Terreni, M Longoni, N Boari, P Mortini, C Doglioni, P Riva Oncology reports 18 (1), 249-252, 2007 | 30 | 2007 |
DNA Microarray Analysis Identifies CKS2 and LEPR as Potential Markers of Meningioma Recurrence F Menghi, FN Orzan, M Eoli, M Farinotti, E Maderna, F Pisati, ... The oncologist 16 (10), 1440-1450, 2011 | 27 | 2011 |
Cerebrospinal fluid tumor DNA for liquid biopsy in glioma patients’ management: Close to the clinic? M Simonelli, A Dipasquale, F Orzan, E Lorenzi, P Persico, P Navarria, ... Critical Reviews in Oncology/Hematology 146, 102879, 2020 | 26 | 2020 |
Uncommon Alu-mediated NF1 microdeletion with a breakpoint inside the NF1 gene C Gervasini, M Venturin, F Orzan, A Friso, M Clementi, R Tenconi, ... Genomics 85 (2), 273-279, 2005 | 24 | 2005 |
ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma F De Bacco, F Orzan, J Erriquez, E Casanova, L Barault, R Albano, ... Cell Reports 36 (4), 2021 | 19 | 2021 |
Liquid biopsy of cerebrospinal fluid enables selective profiling of glioma molecular subtypes at first clinical presentation F Orzan, F De Bacco, E Lazzarini, G Crisafulli, A Gasparini, A Dipasquale, ... Clinical Cancer Research 29 (7), 1252-1266, 2023 | 17 | 2023 |
A simplified integrated molecular and immunohistochemistry-based algorithm allows high accuracy prediction of glioblastoma transcriptional subtypes F Orzan, F Pagani, M Cominelli, L Triggiani, S Calza, F De Bacco, ... Laboratory Investigation 100 (10), 1330-1344, 2020 | 16 | 2020 |
Evolutionary genomic remodelling of the human 4q subtelomere (4q35. 2) B Bodega, MF Cardone, S Müller, M Neusser, F Orzan, E Rossi, ... BMC evolutionary biology 7, 1-13, 2007 | 13 | 2007 |
Breakpoint characterization of a novel NF1 multiexonic deletion: a case showing expression of the mutated allele F Orzan, M Stroppi, M Venturin, MC Valero, C Hernández, P Riva neurogenetics 9, 95-100, 2008 | 6 | 2008 |