| Detergent-free purification of ABC (ATP-binding-cassette) transporters S Gulati, M Jamshad, TJ Knowles, KA Morrison, R Downing, N Cant, ... Biochemical Journal 461 (2), 269-278, 2014 | 244 | 2014 |
| The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence A Rothnie, D Theron, L Soceneantu, C Martin, M Traikia, G Berridge, ... European Biophysics Journal 30, 430-442, 2001 | 158 | 2001 |
| Towards understanding promiscuity in multidrug efflux pumps K Wong, J Ma, A Rothnie, PC Biggin, ID Kerr Trends in biochemical sciences 39 (1), 8-16, 2014 | 152 | 2014 |
| Membrane protein extraction and purification using styrene–maleic acid (SMA) copolymer: effect of variations in polymer structure KA Morrison, A Akram, A Mathews, ZA Khan, JH Patel, C Zhou, DJ Hardy, ... Biochemical Journal 473 (23), 4349-4360, 2016 | 151 | 2016 |
| An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles SCL Hall, C Tognoloni, J Charlton, ÉC Bragginton, AJ Rothnie, P Sridhar, ... Nanoscale 10 (22), 10609-10619, 2018 | 109 | 2018 |
| Structure and function of membrane proteins encapsulated in a polymer-bound lipid bilayer NL Pollock, SC Lee, JH Patel, AA Gulamhussein, AJ Rothnie Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (4), 809-817, 2018 | 104 | 2018 |
| A sequential mechanism for clathrin cage disassembly by 70-kDa heat-shock cognate protein (Hsc70) and auxilin A Rothnie, AR Clarke, P Kuzmic, A Cameron, CJ Smith Proceedings of the National Academy of Sciences 108 (17), 6927-6932, 2011 | 74 | 2011 |
| The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein A Rothnie, J Storm, J Campbell, KJ Linton, ID Kerr, R Callaghan Journal of Biological Chemistry 279 (33), 34913-34921, 2004 | 73 | 2004 |
| A comparison of SMA (styrene maleic acid) and DIBMA (di-isobutylene maleic acid) for membrane protein purification AA Gulamhussein, R Uddin, BJ Tighe, DR Poyner, AJ Rothnie Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (7), 183281, 2020 | 72 | 2020 |
| The synthesis of recombinant membrane proteins in yeast for structural studies SJ Routledge, L Mikaliunaite, A Patel, M Clare, SP Cartwright, Z Bawa, ... Methods 95, 26-37, 2016 | 70 | 2016 |
| Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1/ABCC1) A Rothnie, R Callaghan, RG Deeley, SPC Cole Journal of biological chemistry 281 (20), 13906-13914, 2006 | 64 | 2006 |
| APP controls the formation of PI(3,5)P2 vesicles through its binding of the PIKfyve complex H Currinn, B Guscott, Z Balklava, A Rothnie, T Wassmer Cellular and molecular life sciences 73, 393-408, 2016 | 63 | 2016 |
| The expression of P-glycoprotein does influence the distribution of novel fluorescent compounds in solid tumour models C Martin, J Walker, A Rothnie, R Callaghan British journal of cancer 89 (8), 1581-1589, 2003 | 63 | 2003 |
| Overcoming bottlenecks in the membrane protein structural biology pipeline D Hardy, RM Bill, A Jawhari, AJ Rothnie Biochemical Society Transactions 44 (3), 838-844, 2016 | 60 | 2016 |
| Expression and purification of recombinant G protein-coupled receptors: A review DN Wiseman, A Otchere, JH Patel, R Uddin, NL Pollock, SJ Routledge, ... Protein Expression and Purification 167, 105524, 2020 | 55 | 2020 |
| Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1) K Maeno, A Nakajima, G Conseil, A Rothnie, RG Deeley, SPC Cole Drug metabolism and disposition 37 (7), 1411-1420, 2009 | 53 | 2009 |
| Expression of eukaryotic membrane proteins in eukaryotic and prokaryotic hosts A Kesidis, P Depping, A Lodé, A Vaitsopoulou, RM Bill, AD Goddard, ... Methods 180, 3-18, 2020 | 52 | 2020 |
| Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport A Rothnie, G Conseil, AYT Lau, RG Deeley, SPC Cole Molecular pharmacology 74 (6), 1630-1640, 2008 | 50 | 2008 |
| AP-2-complex-mediated endocytosis of Drosophila Crumbs regulates polarity by antagonizing Stardust YH Lin, H Currinn, SM Pocha, A Rothnie, T Wassmer, E Knust Journal of cell science 128 (24), 4538-4549, 2015 | 44 | 2015 |
| The yin and yang of solubilization and stabilization for wild-type and full-length membrane protein D Hardy, ED Mandon, AJ Rothnie, A Jawhari Methods 147, 118-125, 2018 | 42 | 2018 |
