Cell lines: a tool for in vitro drug metabolism studies MJ Gomez-Lechon, MT Donato, A Lahoz, JV Castell Current drug metabolism 9 (1), 1-11, 2008 | 408 | 2008 |
Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells S Antherieu, C Chesne, R Li, S Camus, A Lahoz, L Picazo, M Turpeinen, ... Drug Metabolism and Disposition 38 (3), 516-525, 2010 | 287 | 2010 |
Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method JC García-Cañaveras, MT Donato, JV Castell, A Lahoz Journal of lipid research 53 (10), 2231-2241, 2012 | 264 | 2012 |
Mammalian cell metabolomics: experimental design and sample preparation Z León, JC García‐Cañaveras, MT Donato, A Lahoz Electrophoresis 34 (19), 2762-2775, 2013 | 218 | 2013 |
Unprecedented Blue Intrinsic Photoluminescence from Hyperbranched and Linear Polyethylenimines: Polymer Architectures and pH‐Effects L Pastor‐Pérez, Y Chen, Z Shen, A Lahoz, SE Stiriba Macromolecular rapid communications 28 (13), 1404-1409, 2007 | 194 | 2007 |
A score model for the continuous grading of early allograft dysfunction severity E Pareja, M Cortes, D Hervás, J Mir, A Valdivieso, JV Castell, A Lahoz Liver Transplantation 21 (1), 38-46, 2015 | 185 | 2015 |
Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts MT Donato, A Lahoz, N Jimenez, G Pérez, A Serralta, J Mir, JV Castell, ... Drug metabolism and disposition 34 (9), 1556-1562, 2006 | 169 | 2006 |
A comprehensive untargeted metabonomic analysis of human steatotic liver tissue by RP and HILIC chromatography coupled to mass spectrometry reveals important metabolic alterations JC García-Canaveras, MT Donato, JV Castell, A Lahoz Journal of proteome research 10 (10), 4825-4834, 2011 | 152 | 2011 |
Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs L Tolosa, S Pinto, MT Donato, A Lahoz, JV Castell, JE O’Connor, ... Toxicological Sciences 127 (1), 187-198, 2012 | 139 | 2012 |
In vitro evaluation of potential hepatotoxicity induced by drugs MJ Gomez-Lechon, A Lahoz, L Gombau, JV Castell, MT Donato Current pharmaceutical design 16 (17), 1963-1977, 2010 | 139 | 2010 |
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ... Nature chemical biology 16 (7), 731-739, 2020 | 122 | 2020 |
Polypodium leucotomos extract: antioxidant activity and disposition L Gombau, F García, A Lahoz, M Fabre, P Roda-Navarro, P Majano, ... Toxicology in vitro 20 (4), 464-471, 2006 | 99 | 2006 |
Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes K Mathijs, AS Kienhuis, KJJ Brauers, DGJ Jennen, A Lahoz, ... Drug Metabolism and Disposition 37 (6), 1305-1311, 2009 | 90 | 2009 |
Prediagnostic plasma bile acid levels and colon cancer risk: a prospective study T Kühn, M Stepien, M López-Nogueroles, A Damms-Machado, ... JNCI: Journal of the National Cancer Institute 112 (5), 516-524, 2020 | 85 | 2020 |
Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies MT Donato, S Montero, JV Castell, MJ Gómez-Lechón, A Lahoz Analytical and bioanalytical chemistry 396, 2251-2263, 2010 | 82 | 2010 |
Metabolomics discloses donor liver biomarkers associated with early allograft dysfunction M Cortes, E Pareja, JC García-Cañaveras, M Teresa Donato, S Montero, ... Journal of Hepatology, 2014 | 78 | 2014 |
Human Embryonic Stem Cell Derived Hepatocyte-Like Cells as a Tool for In Vitro Hazard Assessment of Chemical Carcinogenicity R Yildirimman, G Brolén, M Vilardell, G Eriksson, J Synnergren, ... Toxicological Sciences 124 (2), 278-290, 2011 | 75 | 2011 |
Chemometric approaches to improve PLSDA model outcome for predicting human non-alcoholic fatty liver disease using UPLC-MS as a metabolic profiling tool G Quintás, N Portillo, JC García-Cañaveras, JV Castell, A Ferrer, A Lahoz Metabolomics 8, 86-98, 2012 | 74 | 2012 |
A metabolomics cell-based approach for anticipating and investigating drug-induced liver injury JC García-Cañaveras, JV Castell, MT Donato, A Lahoz Scientific reports 6 (1), 27239, 2016 | 73 | 2016 |
Interactions of polyphenols with the P450 system: possible implications on human therapeutics. I Rodeiro, MT Donato, A Lahoz, G Garrido, R Delgado, MJ Gómez-Lechón Mini reviews in medicinal chemistry 8 (2), 97-106, 2008 | 71 | 2008 |