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Matteo Gentili
Matteo Gentili
Broad Institute - Cell Circuits
Verified email at broadinstitute.org
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Cited by
Year
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
M Raab, M Gentili, H de Belly, HR Thiam, P Vargas, AJ Jimenez, ...
Science 352 (6283), 359-362, 2016
8152016
Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations
N Jeremiah, B Neven, M Gentili, I Callebaut, S Maschalidi, ...
The Journal of clinical investigation 124 (12), 5516-5520, 2014
4942014
The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells
X Lahaye, T Satoh, M Gentili, S Cerboni, C Conrad, I Hurbain, A El Marjou, ...
Immunity 39 (6), 1132-1142, 2013
4222013
Transmission of innate immune signaling by packaging of cGAMP in viral particles
M Gentili, J Kowal, M Tkach, T Satoh, X Lahaye, C Conrad, M Boyron, ...
Science 349 (6253), 1232-1236, 2015
2982015
Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes
S Cerboni, N Jeremiah, M Gentili, U Gehrmann, C Conrad, ...
Journal of Experimental Medicine 214 (6), 1769-1785, 2017
2232017
The N-terminal domain of cGAS determines preferential association with centromeric DNA and innate immune activation in the nucleus
M Gentili, X Lahaye, F Nadalin, GPF Nader, EP Lombardi, S Herve, ...
Cell reports 26 (9), 2377-2393. e13, 2019
2212019
NONO detects the nuclear HIV capsid to promote cGAS-mediated innate immune activation
X Lahaye, M Gentili, A Silvin, C Conrad, L Picard, M Jouve, E Zueva, ...
Cell 175 (2), 488-501. e22, 2018
1952018
Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions
MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess, M Gentili, ...
Cell Reports Medicine 2 (5), 2021
1902021
SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication
Y Zhang, R Guo, SH Kim, H Shah, S Zhang, JH Liang, Y Fang, M Gentili, ...
Nature communications 12 (1), 1676, 2021
1282021
Compromised nuclear envelope integrity drives TREX1-dependent DNA damage and tumor cell invasion
GP de Freitas Nader, S Agüera-Gonzalez, F Routet, M Gratia, M Maurin, ...
Cell 184 (20), 5230-5246. e22, 2021
1172021
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs
S Weingarten-Gabbay, S Klaeger, S Sarkizova, LR Pearlman, DY Chen, ...
Cell 184 (15), 3962-3980. e17, 2021
1092021
SARS-CoV-2 viremia is associated with distinct proteomic pathways and predicts COVID-19 outcomes
Y Li, AM Schneider, A Mehta, M Sade-Feldman, KR Kays, M Gentili, ...
The Journal of Clinical Investigation 131 (13), 2021
1082021
Diversity of pathogen sensors in dendritic cells
S Cerboni, M Gentili, N Manel
Advances in immunology 120, 211-237, 2013
582013
Nuclear envelope protein SUN2 promotes cyclophilin-A-dependent steps of HIV replication
X Lahaye, T Satoh, M Gentili, S Cerboni, A Silvin, C Conrad, ...
Cell reports 15 (4), 879-892, 2016
492016
A cell-free nanobody engineering platform rapidly generates SARS-CoV-2 neutralizing nanobodies
X Chen, M Gentili, N Hacohen, A Regev
Nature communications 12 (1), 5506, 2021
472021
Sensing of HIV-1 entry triggers a type I interferon response in human primary macrophages
J Decalf, M Desdouits, V Rodrigues, FX Gobert, M Gentili, ...
Journal of virology 91 (15), 10.1128/jvi. 00147-17, 2017
452017
Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients
MR Filbin, A Mehta, AM Schneider, KR Kays, JR Guess, M Gentili, ...
BioRxiv, 2020.11. 02.365536, 2020
432020
Human STING is a proton channel
B Liu, RJ Carlson, IS Pires, M Gentili, E Feng, Q Hellier, MA Schwartz, ...
Science 381 (6657), 508-514, 2023
412023
ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling
M Gentili, B Liu, M Papanastasiou, D Dele-Oni, MA Schwartz, RJ Carlson, ...
Nature Communications 14 (1), 611, 2023
252023
SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs
S Weingarten-Gabbay, S Klaeger, S Sarkizova, LR Pearlman, DY Chen, ...
bioRxiv, 2020.10. 02.324145, 2020
252020
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