Ludmil B. Alexandrov
Ludmil B. Alexandrov
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Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
71922013
Mutational Processes Molding the Genomes of 21 Breast Cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
15962012
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ...
Nature 534 (7605), 47-54, 2016
14572016
The Life History of 21 Breast Cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
12872012
High burden and pervasive positive selection of somatic mutations in normal human skin
I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ...
Science 348 (6237), 880-886, 2015
11432015
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
K Schulze, S Imbeaud, E Letouzé, LB Alexandrov, J Calderaro, ...
Nature Genetics 47 (5), 505–511, 2015
10742015
The evolutionary history of lethal metastatic prostate cancer
G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ...
Nature 520 (7547), 353–357, 2015
10512015
The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AWT Ng, Y Wu, A Boot, ...
Nature 578 (7793), 94-101, 2020
8832020
Deciphering Signatures of Mutational Processes Operative in Human Cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton
Cell Reports 3 (1), 246-259, 2013
8782013
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...
Nature Communications 5 (2997), 2014
7432014
Whole-genome landscapes of major melanoma subtypes
NK Hayward, JS Wilmott, N Waddell, PA Johansson, MA Field, K Nones, ...
Nature 545, 175–180, 2017
7262017
Mutational signatures associated with tobacco smoking in human cancer
LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ...
Science 354 (6312), 618-622, 2016
6632016
Clock-like mutational processes in human somatic cells
LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ...
Nature Genetics 47 (12), 1402–1407, 2015
6332015
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ...
Nature Medicine 21 (7), 751-759, 2015
6142015
Timing, rates and spectra of human germline mutation
R Rahbari, A Wuster, SJ Lindsay, RJ Hardwick, LB Alexandrov, S Al Turki, ...
Nature Genetics 48, 126–133, 2016
6092016
Pan-cancer analysis of whole genomes
ICGC Pan-Cancer Analysis of Whole Genomes Consortium
Nature 578 (7793), 82-93, 2020
5852020
Mutational signatures: the patterns of somatic mutations hidden in cancer genomes
LB Alexandrov, MR Stratton
Current Opinion in Genetics & Development 24, 52-60, 2014
4072014
Genomic evolution of breast cancer metastasis and relapse
LR Yates, S Knappskog, D Wedge, JHR Farmery, S Gonzalez, ...
Cancer cell 32 (2), 169-184. e7, 2017
3972017
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ...
Nature 538, 378–382, 2016
3872016
Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours
X Ma, Y Liu, Y Liu, LB Alexandrov, MN Edmonson, C Gawad, X Zhou, Y Li, ...
Nature 555 (7696), 371-376, 2018
3722018
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