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Jeffrey R. Moffitt
Jeffrey R. Moffitt
Assistant Professor, Boston Children's Hospital and Harvard Medical School
Adresse e-mail validée de childrens.harvard.edu - Page d'accueil
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Année
Spatially resolved, highly multiplexed RNA profiling in single cells
KH Chen*, AN Boettiger*, JR Moffitt*, S Wang, X Zhuang
Science 348 (6233), aaa6090, *equal authorship, 2015
19282015
Recent advances in optical tweezers
JR Moffitt, YR Chemla, SB Smith, C Bustamante
Annu. Rev. Biochem. 77, 205-228, 2008
13052008
Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region
JR Moffitt, D Bambah-Mukku, SW Eichhorn, E Vaughn, K Shekhar, ...
Science 362 (6416), eaau5324, 2018
8552018
Super-resolution imaging reveals distinct chromatin folding for different epigenetic states
AN Boettiger, B Bintu, JR Moffitt, S Wang, BJ Beliveau, G Fudenberg, ...
Nature 529 (7586), 418-422, 2016
8252016
Spatial organization of chromatin domains and compartments in single chromosomes
S Wang, JH Su, BJ Beliveau, B Bintu, JR Moffitt, C Wu, X Zhuang
Biophysical Journal 112 (3), 217a, 2017
6222017
High-throughput single-cell gene-expression profiling with multiplexed error-robust fluorescence in situ hybridization
JR Moffitt*`, J Hao`, G Wang`, KH Chen, HP Babcock, X Zhuang*
Proceedings of the National Academy of Sciences 113 (39), *co-corresponding …, 2016
4252016
Characterization and development of photoactivatable fluorescent proteins for single-molecule–based superresolution imaging
S Wang, JR Moffitt, GT Dempsey, XS Xie, X Zhuang
Proceedings of the National Academy of Sciences 111 (23), 8452-8457, 2014
3812014
Differential detection of dual traps improves the spatial resolution of optical tweezers
JR Moffitt*, YR Chemla*, D Izhaky, C Bustamante
Proceedings of the National Academy of Sciences 103 (24), 9006, *equal …, 2006
3772006
Intersubunit coordination in a homomeric ring ATPase
JR Moffitt*, YR Chemla*, K Aathavan, S Grimes, PJ Jardine, DL Anderson, ...
Nature 457 (7228), 446-450, *equal authorship, 2009
3252009
MAFG-driven astrocytes promote CNS inflammation
MA Wheeler, IC Clark, EC Tjon, Z Li, SEJ Zandee, CP Couturier, ...
Nature 578 (7796), 593-599, 2020
3202020
High-performance multiplexed fluorescence in situ hybridization in culture and tissue with matrix imprinting and clearing
JR Moffitt, J Hao, D Bambah-Mukku, T Lu, C Dulac, X Zhuang
Proceedings of the National Academy of Sciences 113 (50), 14456-14461, 2016
2562016
Multiplexed imaging of high-density libraries of RNAs with MERFISH and expansion microscopy
G Wang, JR Moffitt, X Zhuang
Scientific reports 8 (1), 4847, 2018
2152018
The single-cell chemostat: an agarose-based, microfluidic device for high-throughput, single-cell studies of bacteria and bacterial communities
JR Moffitt*, JB Lee*, P Cluzel
Lab Chip, *equal authorship, 2012
2052012
Time-gating improves the spatial resolution of STED microscopy
JR Moffitt*, C Osseforth, J Michaelis*
Optics express 19 (5), 4242-4254, *co-corresponding author, 2011
1702011
RNA Imaging with Multiplexed Error-Robust Fluorescence In Situ Hybridization (MERFISH)
JR Moffitt*, X Zhuang*
Methods in Enzymology, *corresponding author, 2016
1692016
Single–base pair unwinding and asynchronous RNA release by the hepatitis C virus NS3 helicase
W Cheng, SG Arunajadai, JR Moffitt, I Tinoco Jr, C Bustamante
Science 333 (6050), 1746-1749, 2011
1642011
The emerging landscape of spatial profiling technologies
JR Moffitt, E Lundberg, H Heyn
Nature Reviews Genetics 23 (12), 741-759, 2022
1562022
Robust circadian oscillations in growing cyanobacteria require transcriptional feedback
SW Teng, S Mukherji*, JR Moffitt*, S De Buyl*, EK O’shea
Science 340 (6133), 737-740, *equal authorship, 2013
1522013
Spatial organization shapes the turnover of a bacterial transcriptome
JR Moffitt, S Pandey, AN Boettiger, S Wang, X Zhuang
elife 5, e13065, 2016
1492016
Substrate interactions and promiscuity in a viral DNA packaging motor
K Aathavan*, AT Politzer*, A Kaplan*, JR Moffitt*, YR Chemla, S Grimes, ...
Nature 461 (7264), 669-673, *equal authorship, 2009
1292009
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