|Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives|
L Baldi, DL Hacker, M Adam, FM Wurm
Biotechnology letters 29 (5), 677-684, 2007
|Critical Role for Lysines 21 and 22 in Signal-induced, Ubiquitin-mediated Proteolysis of IB|
L Baldi, K Brown, G Franzoso, U Siebenlist
Journal of Biological Chemistry 271 (1), 376-379, 1996
|CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56lck Complexes|
A Arcaro, C Grégoire, TR Bakker, L Baldi, M Jordan, L Goffin, ...
The Journal of experimental medicine 194 (10), 1485-1495, 2001
|Transient gene expression in suspension HEK‐293 cells: application to large‐scale protein production|
L Baldi, N Muller, S Picasso, R Jacquet, P Girard, HP Thanh, E Derow, ...
Biotechnology progress 21 (1), 148-153, 2005
|Recombinant therapeutic protein production in cultivated mammalian cells: current status and future prospects|
M Matasci, DL Hacker, L Baldi, FM Wurm
Drug Discovery Today: Technologies 5 (2-3), e37-e42, 2008
|A simple high-yielding process for transient gene expression in CHO cells|
Y Rajendra, D Kiseljak, L Baldi, DL Hacker, FM Wurm
Journal of biotechnology 153 (1-2), 22-26, 2011
|The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability|
M Matasci, L Baldi, DL Hacker, FM Wurm
Biotechnology and bioengineering 108 (9), 2141-2150, 2011
|DNA delivery with hyperbranched polylysine: A comparative study with linear and dendritic polylysine|
Z Kadlecova, Y Rajendra, M Matasci, L Baldi, DL Hacker, FM Wurm, ...
Journal of Controlled Release 169 (3), 276-288, 2013
|Sustained activation and tumor targeting of NKT cells using a CD1d–anti-HER2–scFv fusion protein induce antitumor effects in mice|
K Stirnemann, JF Romero, L Baldi, B Robert, V Cesson, GS Besra, ...
The Journal of clinical investigation 118 (3), 994-1005, 2008
|Comparative study on the in vitro cytotoxicity of linear, dendritic, and hyperbranched polylysine analogues|
Z Kadlecova, L Baldi, D Hacker, FM Wurm, HA Klok
Biomacromolecules 13 (10), 3127-3137, 2012
|Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells|
S Wulhfard, L Baldi, DL Hacker, F Wurm
Journal of biotechnology 148 (2-3), 128-132, 2010
|Specific recognition of the viral protein UL18 by CD85j/LIR-1/ILT2 on CD8+ T cells mediates the non-MHC-restricted lysis of human cytomegalovirus-infected cells|
D Saverino, F Ghiotto, A Merlo, S Bruno, L Battini, M Occhino, M Maffei, ...
The Journal of Immunology 172 (9), 5629-5637, 2004
|Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells|
DL Hacker, D Kiseljak, Y Rajendra, S Thurnheer, L Baldi, FM Wurm
Protein expression and purification 92 (1), 67-76, 2013
|The signal response of IkappaB alpha is regulated by transferable N-and C-terminal domains.|
K Brown, G Franzoso, L Baldi, L Carlson, L Mills, YC Lin, S Gerstberger, ...
Molecular and Cellular Biology 17 (6), 3021-3027, 1997
|Natural anti-FcεRIα autoantibodies may interfere with diagnostic tests for autoimmune urticaria|
JM Pachlopnik, MP Horn, M Fux, M Dahinden, M Mandallaz, ...
Journal of autoimmunity 22 (1), 43-51, 2004
|Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers–a Swiss contribution|
S Werner, R Eibl, C Lettenbauer, M Röll, D Eibl, M De Jesus, X Zhang, ...
CHIMIA International Journal for Chemistry 64 (11), 819-823, 2010
|Natural anti-FcεRIα autoantibodies isolated from healthy donors and chronic idiopathic urticaria patients reveal a restricted repertoire and autoreactivity on human basophils|
SM Miescher, MP Horn, JM Pachlopnik, L Baldi, M Vogel, BM Stadler
Human antibodies 10 (3-4), 119-126, 2001
|High-titer, serum-free production of adeno-associated virus vectors by polyethyleneimine-mediated plasmid transfection in mammalian suspension cells|
M Hildinger, L Baldi, M Stettler, FM Wurm
Biotechnology letters 29 (11), 1713-1721, 2007
|Role of non‐specific DNA in reducing coding DNA requirement for transient gene expression with CHO and HEK‐293E cells|
Y Rajendra, D Kiseljak, S Manoli, L Baldi, DL Hacker, FM Wurm
Biotechnology and bioengineering 109 (9), 2271-2278, 2012
|Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools|
S Balasubramanian, M Matasci, Z Kadlecova, L Baldi, DL Hacker, ...
Journal of biotechnology 200, 61-69, 2015