Lucia Baldi
Lucia Baldi
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Recombinant protein production by large-scale transient gene expression in mammalian cells: state of the art and future perspectives
L Baldi, DL Hacker, M Adam, FM Wurm
Biotechnology letters 29 (5), 677-684, 2007
3122007
Critical Role for Lysines 21 and 22 in Signal-induced, Ubiquitin-mediated Proteolysis of IB
L Baldi, K Brown, G Franzoso, U Siebenlist
Journal of Biological Chemistry 271 (1), 376-379, 1996
2371996
CD8β Endows CD8 with Efficient Coreceptor Function by Coupling T Cell Receptor/CD3 to Raft-associated CD8/p56lck Complexes
A Arcaro, C Grégoire, TR Bakker, L Baldi, M Jordan, L Goffin, ...
The Journal of experimental medicine 194 (10), 1485-1495, 2001
2302001
Transient gene expression in suspension HEK‐293 cells: application to large‐scale protein production
L Baldi, N Muller, S Picasso, R Jacquet, P Girard, HP Thanh, E Derow, ...
Biotechnology progress 21 (1), 148-153, 2005
1622005
Recombinant therapeutic protein production in cultivated mammalian cells: current status and future prospects
M Matasci, DL Hacker, L Baldi, FM Wurm
Drug Discovery Today: Technologies 5 (2-3), e37-e42, 2008
1272008
A simple high-yielding process for transient gene expression in CHO cells
Y Rajendra, D Kiseljak, L Baldi, DL Hacker, FM Wurm
Journal of biotechnology 153 (1-2), 22-26, 2011
1092011
The PiggyBac transposon enhances the frequency of CHO stable cell line generation and yields recombinant lines with superior productivity and stability
M Matasci, L Baldi, DL Hacker, FM Wurm
Biotechnology and bioengineering 108 (9), 2141-2150, 2011
972011
DNA delivery with hyperbranched polylysine: A comparative study with linear and dendritic polylysine
Z Kadlecova, Y Rajendra, M Matasci, L Baldi, DL Hacker, FM Wurm, ...
Journal of Controlled Release 169 (3), 276-288, 2013
942013
Sustained activation and tumor targeting of NKT cells using a CD1d–anti-HER2–scFv fusion protein induce antitumor effects in mice
K Stirnemann, JF Romero, L Baldi, B Robert, V Cesson, GS Besra, ...
The Journal of clinical investigation 118 (3), 994-1005, 2008
852008
Comparative study on the in vitro cytotoxicity of linear, dendritic, and hyperbranched polylysine analogues
Z Kadlecova, L Baldi, D Hacker, FM Wurm, HA Klok
Biomacromolecules 13 (10), 3127-3137, 2012
802012
Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells
S Wulhfard, L Baldi, DL Hacker, F Wurm
Journal of biotechnology 148 (2-3), 128-132, 2010
702010
Specific recognition of the viral protein UL18 by CD85j/LIR-1/ILT2 on CD8+ T cells mediates the non-MHC-restricted lysis of human cytomegalovirus-infected cells
D Saverino, F Ghiotto, A Merlo, S Bruno, L Battini, M Occhino, M Maffei, ...
The Journal of Immunology 172 (9), 5629-5637, 2004
692004
Polyethyleneimine-based transient gene expression processes for suspension-adapted HEK-293E and CHO-DG44 cells
DL Hacker, D Kiseljak, Y Rajendra, S Thurnheer, L Baldi, FM Wurm
Protein expression and purification 92 (1), 67-76, 2013
662013
The signal response of IkappaB alpha is regulated by transferable N-and C-terminal domains.
K Brown, G Franzoso, L Baldi, L Carlson, L Mills, YC Lin, S Gerstberger, ...
Molecular and Cellular Biology 17 (6), 3021-3027, 1997
541997
Natural anti-FcεRIα autoantibodies may interfere with diagnostic tests for autoimmune urticaria
JM Pachlopnik, MP Horn, M Fux, M Dahinden, M Mandallaz, ...
Journal of autoimmunity 22 (1), 43-51, 2004
482004
Innovative, non-stirred bioreactors in scales from milliliters up to 1000 liters for suspension cultures of cells using disposable bags and containers–a Swiss contribution
S Werner, R Eibl, C Lettenbauer, M Röll, D Eibl, M De Jesus, X Zhang, ...
CHIMIA International Journal for Chemistry 64 (11), 819-823, 2010
452010
Natural anti-FcεRIα autoantibodies isolated from healthy donors and chronic idiopathic urticaria patients reveal a restricted repertoire and autoreactivity on human basophils
SM Miescher, MP Horn, JM Pachlopnik, L Baldi, M Vogel, BM Stadler
Human antibodies 10 (3-4), 119-126, 2001
432001
High-titer, serum-free production of adeno-associated virus vectors by polyethyleneimine-mediated plasmid transfection in mammalian suspension cells
M Hildinger, L Baldi, M Stettler, FM Wurm
Biotechnology letters 29 (11), 1713-1721, 2007
422007
Role of non‐specific DNA in reducing coding DNA requirement for transient gene expression with CHO and HEK‐293E cells
Y Rajendra, D Kiseljak, S Manoli, L Baldi, DL Hacker, FM Wurm
Biotechnology and bioengineering 109 (9), 2271-2278, 2012
382012
Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools
S Balasubramanian, M Matasci, Z Kadlecova, L Baldi, DL Hacker, ...
Journal of biotechnology 200, 61-69, 2015
362015
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