Defining substrate and blocker activity of alanine-serine-cysteine transporter 2 (ASCT2) ligands with novel serine analogs T Albers, W Marsiglia, T Thomas, A Gameiro, C Grewer Molecular pharmacology 81 (3), 356-365, 2012 | 45 | 2012 |
Two FGF receptor kinase molecules act in concert to recruit and transphosphorylate phospholipase Cγ Z Huang, WM Marsiglia, UB Roy, N Rahimi, D Ilghari, H Wang, H Chen, ... Molecular cell 61 (1), 98-110, 2016 | 27 | 2016 |
Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases H Chen, WM Marsiglia, MK Cho, Z Huang, J Deng, SP Blais, W Gai, ... Elife 6, e21137, 2017 | 23 | 2017 |
Multiple frequency saturation pulses reduce CEST acquisition time for quantifying conformational exchange in biomolecules M Leninger, WM Marsiglia, A Jerschow, NJ Traaseth Journal of biomolecular NMR 71 (1), 19-30, 2018 | 10 | 2018 |
Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF A Gao, N Vasilyev, DJ Luciano, R Levenson-Palmer, J Richards, ... Nucleic acids research 46 (13), 6841-6856, 2018 | 8 | 2018 |
Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation L Chen, WM Marsiglia, H Chen, J Katigbak, H Erdjument-Bromage, ... Nature Chemical Biology 16 (3), 267-277, 2020 | 5 | 2020 |
Structural basis for the action of the drug trametinib at KSR-bound MEK ZM Khan, AM Real, WM Marsiglia, A Chow, ME Duffy, JR Yerabolu, ... Nature 588 (7838), 509-514, 2020 | 3 | 2020 |
A Conserved Allosteric Pathway in Tyrosine Kinase Regulation WM Marsiglia, J Katigbak, S Zheng, M Mohammadi, Y Zhang, NJ Traaseth Structure 27 (8), 1308-1315. e3, 2019 | 3 | 2019 |
A CURE Biochemistry Laboratory Module to Study Protein–Protein Interactions by NMR Spectroscopy WM Marsiglia, R Qamra, KM Jackson, NJ Traaseth Journal of Chemical Education 97 (2), 437-442, 2020 | 2 | 2020 |
TRAMETINIB PROMOTES MEK BINDING TO THE RAF-FAMILY PSEUDOKINASE KSR ZM Khan, AM Real, WM Marsiglia, A Chow, ME Duffy, JR Yerabolu CANCER DISCOVERY 10 (11), 1624-1624, 2020 | | 2020 |
Ploidy Leads a Molecular Motor to Walk Different Paths to Drug Resistance AM Real, WM Marsiglia, AC Dar Cell Chemical Biology 27 (7), 770-772, 2020 | | 2020 |
Elucidating the Activating Mechanism of Gatekeeper Mutations on Receptor Tyrosine Kinases A Besch, W Marsiglia, M Mohammadi, Y Zhang, N Traaseth Biophysical Journal 118 (3), 53a, 2020 | | 2020 |
Allostery and Conformational Dynamics in Tyrosine Kinase Regulation W Marsiglia, J Katigbak, S Zheng, M Mohammadi, Y Zhang, N Traaseth Biophysical Journal 118 (3), 522a, 2020 | | 2020 |
Characterization of Disease Causing Mutations Associated with FGF Receptor Tyrosine Kinases using NMR Spectroscopy WM Marsiglia, H Chen, M Cho, M Mohammadi, NJ Traaseth Biophysical Journal 112 (3), 64a, 2017 | | 2017 |
NMR Experiments on Wild-Type and Mutant Fibroblast Growth Factor Receptor Kinases Reveal Conformational Dynamics Associated with Enzyme Activation W Marsiglia, H Chen, M Cho, M Mohammadi, NJ Traaseth Biophysical Journal 110 (3), 220a, 2016 | | 2016 |
Supplemental Information Two FGFR Kinase Molecules Act in Concert to Recruit and Transphosphorylate PLCγ Z Huang, WM Marsiglia, UB Roy, N Rahimi, D Ilghari, H Wang, H Chen, ... | | |