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Charles H. Li
Charles H. Li
Choate, Hall & Stewart LLP
Adresse e-mail validée de choate.com
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Coactivator condensation at super-enhancers links phase separation and gene control
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
Science 361 (6400), eaar3958, 2018
18772018
Transcription factors activate genes through the phase-separation capacity of their activation domains
A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ...
Cell 175 (7), 1842-1855. e16, 2018
13382018
Mediator and RNA polymerase II clusters associate in transcription-dependent condensates
WK Cho, JH Spille, M Hecht, C Lee, C Li, V Grube, II Cisse
Science 361 (6400), 412-415, 2018
10802018
Activation of proto-oncogenes by disruption of chromosome neighborhoods
D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ...
Science 351 (6280), 1454-1458, 2016
10332016
YY1 is a structural regulator of enhancer-promoter loops
AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ...
Cell 171 (7), 1573-1588. e28, 2017
8562017
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene
XS Liu, H Wu, M Krzisch, X Wu, J Graef, J Muffat, D Hnisz, CH Li, B Yuan, ...
Cell 172 (5), 979-992. e6, 2018
4462018
Partitioning of cancer therapeutics in nuclear condensates
IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ...
Science 368 (6497), 1386-1392, 2020
3142020
Mediator condensates localize signaling factors to key cell identity genes
AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ...
Molecular Cell 76 (5), 753-766. e6, 2019
2032019
MeCP2 links heterochromatin condensates and neurodevelopmental disease
CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ...
Nature, 1-8, 2020
1342020
Small genomic insertions form enhancers that misregulate oncogenes
BJ Abraham, D Hnisz, AS Weintraub, N Kwiatkowski, CH Li, Z Li, ...
Nature communications 8, 14385, 2017
912017
Engineering of a histone-recognition domain in Dnmt3a alters the epigenetic landscape and phenotypic features of mouse ESCs
KM Noh, H Wang, HR Kim, W Wenderski, F Fang, CH Li, S Dewell, ...
Molecular cell 59 (1), 89-103, 2015
912015
Chromatin kinases act on transcription factors and histone tails in regulation of inducible transcription
SZ Josefowicz, M Shimada, A Armache, CH Li, RM Miller, S Lin, A Yang, ...
Molecular cell 64 (2), 347-361, 2016
682016
Differential cofactor dependencies define distinct types of human enhancers
C Neumayr, V Haberle, L Serebreni, K Karner, O Hendy, A Boija, ...
Nature, 1-8, 2022
532022
Regulation and dysregulation of chromosome structure in cancer
D Hnisz, J Schuijers, CH Li, RA Young
Annual Review of Cancer Biology 2, 21-40, 2018
372018
Multiplex epigenome editing of MECP2 to rescue Rett syndrome neurons
J Qian, X Guan, B Xie, C Xu, J Niu, X Tang, CH Li, HM Colecraft, ...
Science Translational Medicine 15 (679), eadd4666, 2023
242023
Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription
S Pomplun, M Jbara, CK Schissel, S Wilson Hawken, A Boija, C Li, I Klein, ...
ACS Central Science, 2021
192021
Methods of altering gene expression by perturbing transcription factor multimers that structure regulatory loops
RA Young, AS Weintraub, CH Li, AA Sigova
US Patent App. 16/476,868, 2019
2019
Three-dimensional gene regulatory landscapes in normal and cancer cells
BJ Abraham, YE Guo, D Hnisz, CH Li, AS Weintraub, DS Day, J Schuijers, ...
Cancer Research 78 (13 Supplement), 971-971, 2018
2018
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