| Interpretation of fluctuation spectra in lipid bilayer simulations EG Brandt, AR Braun, JN Sachs, JF Nagle, O Edholm Biophysical journal 100 (9), 2104-2111, 2011 | 152 | 2011 |
| α-Synuclein induces both positive mean curvature and negative Gaussian curvature in membranes AR Braun, E Sevcsik, P Chin, E Rhoades, S Tristram-Nagle, JN Sachs Journal of the American Chemical Society 134 (5), 2613-2620, 2012 | 137 | 2012 |
| Curvature dynamics of α-synuclein familial parkinson disease mutants JD Perlmutter, AR Braun, JN Sachs Journal of biological chemistry 284 (11), 7177-7189, 2009 | 116 | 2009 |
| Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces death receptor 5 networks that are highly organized CC Valley, AK Lewis, DJ Mudaliar, JD Perlmutter, AR Braun, CB Karim, ... Journal of Biological Chemistry 287 (25), 21265-21278, 2012 | 108 | 2012 |
| α-Synuclein-induced membrane remodeling is driven by binding affinity, partition depth, and interleaflet order asymmetry AR Braun, MM Lacy, VC Ducas, E Rhoades, JN Sachs Journal of the American Chemical Society 136 (28), 9962-9972, 2014 | 104 | 2014 |
| Determination of electron density profiles and area from simulations of undulating membranes AR Braun, EG Brandt, O Edholm, JF Nagle, JN Sachs Biophysical journal 100 (9), 2112-2120, 2011 | 68 | 2011 |
| Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies CH Lo, CKW Lim, Z Ding, SP Wickramasinghe, AR Braun, KH Ashe, ... Alzheimer's & Dementia 15 (11), 1489-1502, 2019 | 58 | 2019 |
| Comparing simulations of lipid bilayers to scattering data: the GROMOS 43A1-S3 force field AR Braun, JN Sachs, JF Nagle The Journal of Physical Chemistry B 117 (17), 5065-5072, 2013 | 56 | 2013 |
| X-ray structure, thermodynamics, elastic properties and MD simulations of cardiolipin/dimyristoylphosphatidylcholine mixed membranes AL Boscia, BW Treece, D Mohammadyani, J Klein-Seetharaman, ... Chemistry and Physics of Lipids 178, 1-10, 2014 | 51 | 2014 |
| Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein A West, BE Brummel, AR Braun, E Rhoades, JN Sachs Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (7), 1594-1609, 2016 | 50 | 2016 |
| NaCl interactions with phosphatidylcholine bilayers do not alter membrane structure but induce long-range ordering of ions and water CC Valley, JD Perlmutter, AR Braun, JN Sachs The Journal of Membrane Biology 244, 35-42, 2011 | 49 | 2011 |
| Determining structural and mechanical properties from molecular dynamics simulations of lipid vesicles AR Braun, JN Sachs Journal of chemical theory and computation 10 (9), 4160-4168, 2014 | 31 | 2014 |
| α-Synuclein’s uniquely long amphipathic helix enhances its membrane binding and remodeling capacity AR Braun, MM Lacy, VC Ducas, E Rhoades, JN Sachs The Journal of membrane biology 250, 183-193, 2017 | 29 | 2017 |
| Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation AK Lewis, ZM James, JE McCaffrey, AR Braun, CB Karim, DD Thomas, ... Biophysical journal 106 (6), L21-L24, 2014 | 28 | 2014 |
| Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors AR Braun, EE Liao, M Horvath, P Kalra, K Acosta, MC Young, NN Kochen, ... npj Parkinson's Disease 7 (1), 52, 2021 | 23 | 2021 |
| α-Synuclein reduces tension and increases undulations in simulations of small unilamellar vesicles AR Braun, JN Sachs Biophysical journal 108 (8), 1848-1851, 2015 | 23 | 2015 |
| Death receptor 5 networks require membrane cholesterol for proper structure and function AK Lewis, CC Valley, SL Peery, B Brummel, AR Braun, CB Karim, ... Journal of molecular biology 428 (24), 4843-4855, 2016 | 21 | 2016 |
| Minimal Nucleation State of α-Synuclein Is Stabilized by Dynamic Threonine–Water Networks TD Romo, AK Lewis, AR Braun, A Grossfield, JN Sachs ACS chemical neuroscience 8 (9), 1859-1864, 2017 | 15 | 2017 |
| Polyunsaturated chains in asymmetric lipids disorder raft mixtures and preferentially associate with α-synuclein BE Brummel, AR Braun, JN Sachs Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (4), 529-536, 2017 | 13 | 2017 |
| 35th annual meeting of the European Association for the Study of diabetes: Brussels, Belgium, 28 September–2 October 1999 A Melander, J Olsson, G Lindberg, A Salzman, T Howard, P Stang, ... Diabetologia 42, A1-A330, 1999 | 9 | 1999 |
John F NagleProfessor emeritus of Physics, Carnegie Mellon UniversityAdresse e-mail validée de cmu.edu
