Suivre
David Hot
David Hot
Lab director, Transcriptomics & Applied Genomics, Institut Pasteur de Lille
Adresse e-mail validée de pasteur-lille.fr
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Année
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer
A Couturier-Maillard, T Secher, A Rehman, S Normand, A De Arcangelis, ...
The Journal of clinical investigation 123 (2), 2013
6242013
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
S Normand, A Delanoye-Crespin, A Bressenot, L Huot, T Grandjean, ...
Proceedings of the National Academy of Sciences 108 (23), 9601-9606, 2011
3952011
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease
J Chapuis, D Hot, F Hansmannel, O Kerdraon, S Ferreira, C Hubans, ...
Molecular psychiatry 14 (11), 1004-1016, 2009
2372009
Detection of somatic phages, infectious enteroviruses and enterovirus genomes as indicators of human enteric viral pollution in surface water
D Hot, O Legeay, J Jacques, C Gantzer, Y Caudrelier, K Guyard, M Lange, ...
Water research 37 (19), 4703-4710, 2003
2012003
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
N Blondiaux, M Moune, M Desroses, R Frita, M Flipo, V Mathys, ...
Science 355 (6330), 1206-1211, 2017
1382017
Comparison of mapping algorithms used in high-throughput sequencing: application to Ion Torrent data
S Caboche, C Audebert, Y Lemoine, D Hot
BMC genomics 15, 1-16, 2014
1092014
Enteroviruses can persist with or without active viral replication in cardiac tissue of patients with end-stage ischemic or dilated cardiomyopathy
L Andréoletti, T Bourlet, D Moukassa, L Rey, D Hot, Y Li, V Lambert, ...
The Journal of infectious diseases 182 (4), 1222-1227, 2000
1062000
The Toxoplasma nuclear factor TgAP2XI‐4 controls bradyzoite gene expression and cyst formation
R Walker, M Gissot, MM Croken, L Huot, D Hot, K Kim, S Tomavo
Molecular microbiology 87 (3), 641-655, 2013
1032013
Identification of novel TMPRSS2: ERG mechanisms in prostate cancer metastasis: involvement of MMP9 and PLXNA2
TV Tian, N Tomavo, L Huot, A Flourens, E Bonnelye, S Flajollet, D Hot, ...
Oncogene 33 (17), 2204-2214, 2014
982014
Assessment of common and emerging bioinformatics pipelines for targeted metagenomics
L Siegwald, H Touzet, Y Lemoine, D Hot, C Audebert, S Caboche
PLoS One 12 (1), e0169563, 2017
902017
Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes
C Bougault, E Aubert-Foucher, A Paumier, E Perrier-Groult, L Huot, D Hot, ...
PloS one 7 (5), e36964, 2012
892012
Differential modulation of Bordetella pertussis virulence genes as evidenced by DNA microarray analysis
D Hot, R Antoine, G Renauld-Mongenie, V Caro, B Hennuy, E Levillain, ...
Molecular Genetics and Genomics 269, 475-486, 2003
832003
Airway structural cells regulate TLR5-mediated mucosal adjuvant activity
L Van Maele, D Fougeron, L Janot, A Didierlaurent, D Cayet, J Tabareau, ...
Mucosal immunology 7 (3), 489-500, 2014
792014
ATF6α regulates morphological changes associated with senescence in human fibroblasts
C Druelle, C Drullion, J Desle, N Martin, L Saas, J Cormenier, N Malaquin, ...
Oncotarget 7 (42), 67699, 2016
772016
Temporal analysis of French Bordetella pertussis isolates by comparative whole-genome hybridization
V Caro, D Hot, G Guigon, C Hubans, M Arrivé, G Soubigou, ...
Microbes and infection 8 (8), 2228-2235, 2006
732006
Involvement of the immune system, endocytosis and EIF2 signaling in both genetically determined and sporadic forms of Parkinson's disease
E Mutez, A Nkiliza, K Belarbi, A de Broucker, C Vanbesien-Mailliot, ...
Neurobiology of disease 63, 165-170, 2014
642014
α-Oxo semicarbazone peptide or oligodeoxynucleotide microarrays
C Olivier, D Hot, L Huot, N Ollivier, O El-Mahdi, C Gouyette, T Huynh-Dinh, ...
Bioconjugate chemistry 14 (2), 430-439, 2003
632003
Toxoplasma gondii Alba proteins are involved in translational control of gene expression
M Gissot, R Walker, S Delhaye, TD Alayi, L Huot, D Hot, I Callebaut, ...
Journal of molecular biology 425 (8), 1287-1301, 2013
592013
Transcriptomic analysis in the leech Theromyzon tessulatum: involvement of cystatin B in innate immunity
C Lefebvre, C Cocquerelle, F Vandenbulcke, D Hot, L Huot, Y Lemoine, ...
Biochemical Journal 380 (3), 617-625, 2004
592004
Chronic ingestion of deoxynivalenol at human dietary levels impairs intestinal homeostasis and gut microbiota in mice
C Vignal, M Djouina, M Pichavant, S Caboche, C Waxin, D Beury, D Hot, ...
Archives of Toxicology 92, 2327-2338, 2018
572018
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