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Hai-Young (Anne) Kim
Hai-Young (Anne) Kim
Director at Johnson & Johnson Innovated Medicine
Adresse e-mail validée de its.jnj.com - Page d'accueil
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Pre‐fibrillar α‐synuclein variants with impaired β‐structure increase neurotoxicity in Parkinson's disease models
DP Karpinar, MBG Balija, S Kügler, F Opazo, N Rezaei‐Ghaleh, ...
The EMBO journal 28 (20), 3256-3268, 2009
5692009
Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of α-synuclein
KE Paleologou, AW Schmid, CC Rospigliosi, HY Kim, GR Lamberto, ...
Journal of Biological Chemistry 283 (24), 16895, 2008
4242008
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits α-synuclein oligomerization, and influences synuclein-membrane interactions
KE Paleologou, A Oueslati, G Shakked, CC Rospigliosi, HY Kim, ...
Journal of Neuroscience 30 (9), 3184-3198, 2010
3912010
Structural properties of pore-forming oligomers of α-synuclein
HY Kim, MK Cho, A Kumar, E Maier, C Siebenhaar, S Becker, ...
Journal of the American Chemical Society 131 (47), 17482-17489, 2009
2522009
Structural characterization of α‐synuclein in an aggregation prone state
MK Cho, G Nodet, HY Kim, MR Jensen, P Bernado, CO Fernandez, ...
Protein Science 18 (9), 1840-1846, 2009
1292009
Phosphorylation drives a dynamic switch in serine/arginine-rich proteins
SQ Xiang, V Gapsys, HY Kim, S Bessonov, HH Hsiao, S Möhlmann, ...
Structure 21 (12), 2162-2174, 2013
1152013
Protecting group free radical C–H trifluoromethylation of peptides
N Ichiishi, JP Caldwell, M Lin, W Zhong, X Zhu, E Streckfuss, HY Kim, ...
Chemical science 9 (17), 4168-4175, 2018
1022018
Discovery of selective RNA-binding small molecules by affinity-selection mass spectrometry
NF Rizvi, JA Howe, A Nahvi, DJ Klein, TO Fischmann, HY Kim, MA McCoy, ...
ACS chemical biology 13 (3), 820-831, 2018
882018
Amino acid bulkiness defines the local conformations and dynamics of natively unfolded α-synuclein and tau
MK Cho, HY Kim, P Bernado, CO Fernandez, M Blackledge, ...
Journal of the American Chemical Society 129 (11), 3032-3033, 2007
822007
Correlation of amyloid fibril β‐structure with the unfolded state of α‐synuclein
HY Kim, H Heise, CO Fernandez, M Baldus, M Zweckstetter
ChemBioChem 8 (14), 1671-1674, 2007
762007
Functional and structural characteristics of anticancer peptide Pep27 analogues
DG Lee, KS Hahm, Y Park, HY Kim, W Lee, SC Lim, YK Seo, CH Choi
Cancer cell international 5 (1), 21, 2005
602005
Solution structure of human orexin-A: regulator of appetite and wakefulness
HY Kim, EM Hong, J Kim, WT Lee
BMB Reports 37 (5), 565-573, 2004
572004
Cold denaturation of a protein dimer monitored at atomic resolution
M Jaremko, Ł Jaremko, HY Kim, MK Cho, CD Schwieters, K Giller, ...
Nature chemical biology 9 (4), 264-270, 2013
532013
Dissociation of Amyloid Fibrils of α‐Synuclein in Supercooled Water
HY Kim, MK Cho, D Riedel, CO Fernandez, M Zweckstetter
Angewandte Chemie 120 (27), 5124-5126, 2008
512008
Conserved core of amyloid fibrils of wild type and A30P mutant α‐synuclein
MK Cho, HY Kim, CO Fernandez, S Becker, M Zweckstetter
Protein Science 20 (2), 387-395, 2011
422011
Photoredox Ni-catalyzed peptide C (sp 2)–O cross-coupling: from intermolecular reactions to side chain-to-tail macrocyclization
H Lee, NC Boyer, Q Deng, HY Kim, TK Sawyer, N Sciammetta
Chemical Science 10 (19), 5073-5078, 2019
402019
Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy
T Gruene, MK Cho, I Karyagina, HY Kim, C Grosse, K Giller, ...
Journal of biomolecular NMR 49, 111-119, 2011
312011
Charge‐induced molecular alignment of intrinsically disordered proteins
L Skora, MK Cho, HY Kim, S Becker, CO Fernandez, M Blackledge, ...
Angewandte Chemie International Edition 45 (42), 7012-7015, 2006
262006
Discovery and optimization of rationally designed bicyclic inhibitors of human arginase to enhance cancer immunotherapy
MJ Mitcheltree, D Li, A Achab, A Beard, K Chakravarthy, M Cheng, H Cho, ...
ACS Medicinal Chemistry Letters 11 (4), 582-588, 2020
232020
Automated, high-throughput infrared spectroscopy for secondary structure analysis of protein biopharmaceuticals
LL Liu, L Wang, J Zonderman, JC Rouse, HY Kim
Journal of Pharmaceutical Sciences 109 (10), 3223-3230, 2020
212020
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