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| Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance LA Kirkman, W Zhan, J Visone, A Dziedziech, PK Singh, H Fan, X Tong, ... Proceedings of the National Academy of Sciences 115 (29), E6863-E6870, 2018 | 80 | 2018 |
| The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC R Verity, O Aydemir, NF Brazeau, OJ Watson, NJ Hathaway, ... Nature communications 11 (1), 2107, 2020 | 77 | 2020 |
| Lack of artemisinin resistance in Plasmodium falciparum in Uganda based on parasitological and molecular assays RA Cooper, MD Conrad, QD Watson, SJ Huezo, H Ninsiima, ... Antimicrobial agents and chemotherapy 59 (8), 5061-5064, 2015 | 77 | 2015 |
| Evolution of partial resistance to artemisinins in malaria parasites in Uganda MD Conrad, V Asua, S Garg, D Giesbrecht, K Niaré, S Smith, ... New England Journal of Medicine 389 (8), 722-732, 2023 | 65 | 2023 |
| Impact of antimalarial treatment and chemoprevention on the drug sensitivity of malaria parasites isolated from Ugandan children P Tumwebaze, MD Conrad, A Walakira, N LeClair, O Byaruhanga, ... Antimicrobial agents and chemotherapy 59 (6), 3018-3030, 2015 | 65 | 2015 |
| Changing antimalarial drug sensitivities in Uganda SA Rasmussen, FG Ceja, MD Conrad, PK Tumwebaze, O Byaruhanga, ... Antimicrobial agents and chemotherapy 61 (12), 10.1128/aac. 01516-17, 2017 | 64 | 2017 |
| Changing antimalarial drug resistance patterns identified by surveillance at three sites in Uganda P Tumwebaze, S Tukwasibwe, A Taylor, M Conrad, E Ruhamyankaka, ... The Journal of infectious diseases 215 (4), 631-635, 2017 | 56 | 2017 |
| Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda PK Tumwebaze, MD Conrad, M Okitwi, S Orena, O Byaruhanga, T Katairo, ... Nature communications 13 (1), 6353, 2022 | 47 | 2022 |
| Tools for mass screening of G6PD deficiency: validation of the WST8/1-methoxy-PMS enzymatic assay in Uganda M De Niz, AC Eziefula, L Othieno, E Mbabazi, D Nabukeera, ... Malaria journal 12, 1-11, 2013 | 43 | 2013 |
| Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study PK Tumwebaze, T Katairo, M Okitwi, O Byaruhanga, S Orena, V Asua, ... The Lancet Microbe 2 (9), e441-e449, 2021 | 42 | 2021 |
| The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance JM Murithi, C Pascal, J Bath, X Boulenc, NF Gnädig, CFA Pasaje, ... Science translational medicine 13 (603), eabg6013, 2021 | 34 | 2021 |
| Validation of the ligase detection reaction fluorescent microsphere assay for the detection of Plasmodium falciparum resistance mediating polymorphisms in Uganda S Nankoberanyi, GW Mbogo, NP LeClair, MD Conrad, P Tumwebaze, ... Malaria journal 13, 1-5, 2014 | 33 | 2014 |
| Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series MJ Palmer, X Deng, S Watts, G Krilov, A Gerasyuto, S Kokkonda, ... Journal of medicinal chemistry 64 (9), 6085-6136, 2021 | 31 | 2021 |
| Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors W Zhan, J Visone, T Ouellette, JC Harris, R Wang, H Zhang, PK Singh, ... Journal of medicinal chemistry 62 (13), 6137-6145, 2019 | 30 | 2019 |
| Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance–Mediating Polymorphisms in Uganda MD Conrad, D Mota, M Foster, S Tukwasibwe, J Legac, P Tumwebaze, ... The Journal of Infectious Diseases 216 (8), 1008-1017, 2017 | 30 | 2017 |
| Intermittent preventive treatment with dihydroartemisinin-piperaquine in Ugandan schoolchildren selects for Plasmodium falciparum transporter polymorphisms that modify drug … JI Nankabirwa, MD Conrad, J Legac, S Tukwasibwe, P Tumwebaze, ... Antimicrobial agents and chemotherapy 60 (10), 5649-5654, 2016 | 30 | 2016 |
| Fitness Consequences of Plasmodium falciparum pfmdr1 Polymorphisms Inferred from Ex Vivo Culture of Ugandan Parasites E Ochong, PK Tumwebaze, O Byaruhanga, B Greenhouse, PJ Rosenthal Antimicrobial agents and chemotherapy 57 (9), 4245-4251, 2013 | 23 | 2013 |
| Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice W Zhan, H Zhang, J Ginn, A Leung, YJ Liu, M Michino, A Toita, ... Angewandte Chemie 133 (17), 9365-9369, 2021 | 22 | 2021 |
| Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183 LE de Vries, PAM Jansen, C Barcelo, J Munro, JMJ Verhoef, CFA Pasaje, ... Nature communications 13 (1), 2158, 2022 | 21 | 2022 |
