Suivre
Qian Xie
Qian Xie
Dana-Farber Cancer Institute
Adresse e-mail validée de crystal.harvard.edu
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Functional characterization of wheat ent-kaurene (-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals
K Zhou, M Xu, M Tiernan, Q Xie, T Toyomasu, C Sugawara, M Oku, ...
Phytochemistry 84, 47-55, 2012
612012
Identification of an allosteric signaling network within Tec family kinases
RE Joseph, Q Xie, AH Andreotti
Journal of molecular biology 403 (2), 231-242, 2010
482010
Functional plasticity of the AgrC receptor histidine kinase required for staphylococcal virulence
B Wang, A Zhao, Q Xie, PD Olinares, BT Chait, RP Novick, TW Muir
Cell chemical biology 24 (1), 76-86, 2017
372017
Activation loop dynamics determine the different catalytic efficiencies of B cell–and T cell–specific tec kinases
RE Joseph, I Kleino, TE Wales, Q Xie, DB Fulton, JR Engen, LJ Berg, ...
Science signaling 6 (290), ra76-ra76, 2013
372013
Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the Staphylococcus aureus receptor histidine kinase, AgrC
Q Xie, MM Wiedmann, A Zhao, IR Pagan, RP Novick, H Suga, TW Muir
Chemical Communications 56 (76), 11223-11226, 2020
222020
Substrate recognition of PLCγ1 via a specific docking surface on Itk
Q Xie, RE Joseph, DB Fulton, AH Andreotti
Journal of molecular biology 425 (4), 683-696, 2013
192013
Identification of a molecular latch that regulates staphylococcal virulence
Q Xie, A Zhao, PD Jeffrey, MK Kim, BL Bassler, HA Stone, RP Novick, ...
Cell chemical biology 26 (4), 548-558. e4, 2019
182019
Reconstitution of the S. aureus agr quorum sensing pathway reveals a direct role for the integral membrane protease MroQ in pheromone biosynthesis
A Zhao, SP Bodine, Q Xie, B Wang, G Ram, RP Novick, TW Muir
Proceedings of the National Academy of Sciences 119 (33), e2202661119, 2022
142022
A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase
SE Boyken, N Chopra, Q Xie, RE Joseph, TE Wales, DB Fulton, JR Engen, ...
Journal of molecular biology 426 (21), 3656-3669, 2014
142014
A selective NMR probe to monitor the conformational transition from inactive to active kinase
Q Xie, DB Fulton, AH Andreotti
ACS chemical biology 10 (1), 262-268, 2015
112015
Macrocyclic Peptides: Novel Antibiotic Treatment against Staphylococcus Aureus
A Zhao, Q Xie, T Muir, M Wiedmann, H Suga
2020
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