Oscar krijgsman
Oscar krijgsman
Postdoctoral fellow, Netherlands Cancer Institute
Adresse e-mail validée de nki.nl
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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma
J Müller, O Krijgsman, J Tsoi, L Robert, W Hugo, C Song, X Kong, ...
Nature communications 5 (1), 1-15, 2014
3782014
Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma
CU Blank, EA Rozeman, LF Fanchi, K Sikorska, B van de Wiel, ...
Nature medicine 24 (11), 1655-1661, 2018
2112018
B cells and tertiary lymphoid structures promote immunotherapy response
BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ...
Nature 577 (7791), 549-555, 2020
1942020
Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases
F Weeber, M van de Wetering, M Hoogstraat, KK Dijkstra, O Krijgsman, ...
Proceedings of the National Academy of Sciences 112 (43), 13308-13311, 2015
1822015
CopywriteR: DNA copy number detection from off-target sequence data
T Kuilman, A Velds, K Kemper, M Ranzani, L Bombardelli, M Hoogstraat, ...
Genome biology 16 (1), 49, 2015
1272015
Focal aberrations indicate EYA2 and hsa‐miR‐375 as oncogene and tumor suppressor in cervical carcinogenesis
M Bierkens, O Krijgsman, SM Wilting, L Bosch, A Jaspers, GA Meijer, ...
Genes, Chromosomes and Cancer 52 (1), 56-68, 2013
1102013
TSPYL5 suppresses p53 levels and function by physical interaction with USP7
MT Epping, LAT Meijer, O Krijgsman, JL Bos, PP Pandolfi, R Bernards
Nature cell biology 13 (1), 102-108, 2011
1062011
A diagnostic gene profile for molecular subtyping of breast cancer associated with treatment response
O Krijgsman, P Roepman, W Zwart, JS Carroll, S Tian, FA de Snoo, ...
Breast cancer research and treatment 133 (1), 37-47, 2012
1052012
Microarray-based determination of estrogen receptor, progesterone receptor, and HER2 receptor status in breast cancer
P Roepman, HM Horlings, O Krijgsman, M Kok, JM Bueno-de-Mesquita, ...
Clinical Cancer Research 15 (22), 7003-7011, 2009
1022009
Intra‐and inter‐tumor heterogeneity in a vemurafenib‐resistant melanoma patient and derived xenografts
K Kemper, O Krijgsman, P Cornelissen‐Steijger, A Shahrabi, F Weeber, ...
EMBO molecular medicine 7 (9), 1104-1118, 2015
972015
Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2 …
EA Rozeman, AM Menzies, ACJ van Akkooi, C Adhikari, C Bierman, ...
The Lancet Oncology 20 (7), 948-960, 2019
942019
Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors
J Boshuizen, LA Koopman, O Krijgsman, A Shahrabi, ...
Nature medicine 24 (2), 203, 2018
792018
PRAME expression and clinical outcome of breast cancer
MT Epping, AAM Hart, AM Glas, O Krijgsman, R Bernards
British journal of cancer 99 (3), 398-403, 2008
762008
Transcription factor NFIB is a driver of small cell lung cancer progression in mice and marks metastatic disease in patients
EA Semenova, M Kwon, K Monkhorst, JY Song, R Bhaskaran, ...
Cell reports 16 (3), 631-643, 2016
742016
High lymph node yield is related to microsatellite instability in colon cancer
EJ Belt, EA te Velde, O Krijgsman, RP Brosens, M Tijssen, HF van Essen, ...
Annals of surgical oncology 19 (4), 1222-1230, 2012
632012
Gene‐dosage dependent overexpression at the 13q amplicon identifies DIS3 as candidate oncogene in colorectal cancer progression
FLM de Groen, O Krijgsman, M Tijssen, LEM Vriend, B Ylstra, E Hooijberg, ...
Genes, Chromosomes and Cancer 53 (4), 339-348, 2014
502014
CGH arrays compared for DNA isolated from formalin‐fixed, paraffin‐embedded material
O Krijgsman, D Israeli, JC Haan, HF van Essen, SJ Smeets, PP Eijk, ...
Genes, Chromosomes and Cancer 51 (4), 344-352, 2012
482012
BRAFV600E kinase domain duplication identified in therapy-refractory melanoma patient-derived xenografts
K Kemper, O Krijgsman, X Kong, P Cornelissen-Steijger, A Shahrabi, ...
Cell reports 16 (1), 263-277, 2016
412016
High prevalence and clinical relevance of genes affected by chromosomal breaks in colorectal cancer
E van den Broek, MJJ Dijkstra, O Krijgsman, D Sie, JC Haan, JJH Traets, ...
PLoS One 10 (9), e0138141, 2015
352015
Parallel in vivo and in vitro melanoma RNAi dropout screens reveal synthetic lethality between hypoxia and DNA damage response inhibition
PA Possik, J Müller, C Gerlach, JCN Kenski, X Huang, A Shahrabi, ...
Cell reports 9 (4), 1375-1386, 2014
352014
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