Oscar krijgsman
Oscar krijgsman
Postdoctoral fellow, Netherlands Cancer Institute
Adresse e-mail validée de nki.nl
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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma
J Müller, O Krijgsman, J Tsoi, L Robert, W Hugo, C Song, X Kong, ...
Nature communications 5 (1), 1-15, 2014
3422014
Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma
CU Blank, EA Rozeman, LF Fanchi, K Sikorska, B van de Wiel, ...
Nature medicine 24 (11), 1655-1661, 2018
1672018
Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases
F Weeber, M van de Wetering, M Hoogstraat, KK Dijkstra, O Krijgsman, ...
Proceedings of the National Academy of Sciences 112 (43), 13308-13311, 2015
1522015
CopywriteR: DNA copy number detection from off-target sequence data
T Kuilman, A Velds, K Kemper, M Ranzani, L Bombardelli, M Hoogstraat, ...
Genome biology 16 (1), 49, 2015
1162015
A diagnostic gene profile for molecular subtyping of breast cancer associated with treatment response
O Krijgsman, P Roepman, W Zwart, JS Carroll, S Tian, FA de Snoo, ...
Breast cancer research and treatment 133 (1), 37-47, 2012
1022012
TSPYL5 suppresses p53 levels and function by physical interaction with USP7
MT Epping, LAT Meijer, O Krijgsman, JL Bos, PP Pandolfi, R Bernards
Nature cell biology 13 (1), 102-108, 2011
1012011
Focal aberrations indicate EYA2 and hsa‐miR‐375 as oncogene and tumor suppressor in cervical carcinogenesis
M Bierkens, O Krijgsman, SM Wilting, L Bosch, A Jaspers, GA Meijer, ...
Genes, Chromosomes and Cancer 52 (1), 56-68, 2013
1002013
B cells and tertiary lymphoid structures promote immunotherapy response
BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ...
Nature 577 (7791), 549-555, 2020
992020
Microarray-based determination of estrogen receptor, progesterone receptor, and HER2 receptor status in breast cancer
P Roepman, HM Horlings, O Krijgsman, M Kok, JM Bueno-de-Mesquita, ...
Clinical Cancer Research 15 (22), 7003-7011, 2009
972009
Intra‐and inter‐tumor heterogeneity in a vemurafenib‐resistant melanoma patient and derived xenografts
K Kemper, O Krijgsman, P Cornelissen‐Steijger, A Shahrabi, F Weeber, ...
EMBO molecular medicine 7 (9), 1104-1118, 2015
922015
PRAME expression and clinical outcome of breast cancer
MT Epping, AAM Hart, AM Glas, O Krijgsman, R Bernards
British journal of cancer 99 (3), 398-403, 2008
752008
Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors
J Boshuizen, LA Koopman, O Krijgsman, A Shahrabi, ...
Nature medicine 24 (2), 203, 2018
682018
Transcription factor NFIB is a driver of small cell lung cancer progression in mice and marks metastatic disease in patients
EA Semenova, M Kwon, K Monkhorst, JY Song, R Bhaskaran, ...
Cell reports 16 (3), 631-643, 2016
652016
Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2 …
EA Rozeman, AM Menzies, ACJ van Akkooi, C Adhikari, C Bierman, ...
The Lancet Oncology 20 (7), 948-960, 2019
632019
High lymph node yield is related to microsatellite instability in colon cancer
EJ Belt, EA te Velde, O Krijgsman, RP Brosens, M Tijssen, HF van Essen, ...
Annals of surgical oncology 19 (4), 1222-1230, 2012
622012
CGH arrays compared for DNA isolated from formalin‐fixed, paraffin‐embedded material
O Krijgsman, D Israeli, JC Haan, HF van Essen, SJ Smeets, PP Eijk, ...
Genes, Chromosomes and Cancer 51 (4), 344-352, 2012
482012
Gene‐dosage dependent overexpression at the 13q amplicon identifies DIS3 as candidate oncogene in colorectal cancer progression
FLM de Groen, O Krijgsman, M Tijssen, LEM Vriend, B Ylstra, E Hooijberg, ...
Genes, Chromosomes and Cancer 53 (4), 339-348, 2014
472014
BRAFV600E kinase domain duplication identified in therapy-refractory melanoma patient-derived xenografts
K Kemper, O Krijgsman, X Kong, P Cornelissen-Steijger, A Shahrabi, ...
Cell reports 16 (1), 263-277, 2016
392016
Parallel in vivo and in vitro melanoma RNAi dropout screens reveal synthetic lethality between hypoxia and DNA damage response inhibition
PA Possik, J Müller, C Gerlach, JCN Kenski, X Huang, A Shahrabi, ...
Cell reports 9 (4), 1375-1386, 2014
352014
High prevalence and clinical relevance of genes affected by chromosomal breaks in colorectal cancer
E van den Broek, MJJ Dijkstra, O Krijgsman, D Sie, JC Haan, JJH Traets, ...
PLoS One 10 (9), e0138141, 2015
332015
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