Coactivator condensation at super-enhancers links phase separation and gene control BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ... Science 361 (6400), eaar3958, 2018 | 2027 | 2018 |
Improving the density of jammed disordered packings using ellipsoids A Donev, I Cisse, D Sachs, EA Variano, FH Stillinger, R Connelly, ... Science 303 (5660), 990-993, 2004 | 1450 | 2004 |
Mediator and RNA polymerase II clusters associate in transcription-dependent condensates WK Cho, JH Spille, M Hecht, C Lee, C Li, V Grube, II Cisse Science 361 (6400), 412-415, 2018 | 1166 | 2018 |
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates YE Guo, JC Manteiga, JE Henninger, BR Sabari, A Dall’Agnese, ... Nature 572 (7770), 543-548, 2019 | 547 | 2019 |
Real-Time Dynamics of RNA Polymerase II Clustering in Live Human Cells II Cisse, I Izeddin, SZ Causse, L Boudarene, A Senecal, L Muresan, ... Science, 2013 | 528 | 2013 |
RNA-mediated feedback control of transcriptional condensates JE Henninger, O Oksuz, K Shrinivas, I Sagi, G LeRoy, MM Zheng, ... Cell 184 (1), 207-225. e24, 2021 | 404 | 2021 |
Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus I Izeddin, V Récamier, L Bosanac, II Cissé, L Boudarene, ... Elife 3, e02230, 2014 | 331 | 2014 |
RNA Polymerase II cluster dynamics predict mRNA output in living cells WK Cho, N Jayanth, BP English, T Inoue, JO Andrews, W Conway, ... elife 5, e13617, 2016 | 258 | 2016 |
Mediator condensates localize signaling factors to key cell identity genes AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ... Molecular cell 76 (5), 753-766. e6, 2019 | 217 | 2019 |
A rule of seven in Watson-Crick base-pairing of mismatched sequences II Cisse, H Kim, T Ha Nature structural & molecular biology 19 (6), 623-627, 2012 | 193 | 2012 |
Fueling protein–DNA interactions inside porous nanocontainers I Cisse, B Okumus, C Joo, T Ha Proceedings of the National Academy of Sciences 104 (31), 12646-12650, 2007 | 181 | 2007 |
A first order phase transition mechanism underlies protein aggregation in mammalian cells A Narayanan, A Meriin, JO Andrews, JH Spille, MY Sherman, II Cisse Elife 8, e39695, 2019 | 96 | 2019 |
Hsp70–Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation AB Meriin, A Narayanan, LE Meng, I Alexandrov, X Varelas, II Cissé, ... Proceedings of the National Academy of Sciences 115 (30), E7043-E7052, 2018 | 77 | 2018 |
Super-resolution imaging of fluorescently labeled, endogenous RNA Polymerase II in living cells with CRISPR/Cas9-mediated gene editing WK Cho, N Jayanth, S Mullen, TH Tan, YJ Jung, II Cissé Scientific reports 6 (1), 35949, 2016 | 64 | 2016 |
Hijacking of transcriptional condensates by endogenous retroviruses V Asimi, A Sampath Kumar, H Niskanen, C Riemenschneider, S Hetzel, ... Nature Genetics 54 (8), 1238-1247, 2022 | 44 | 2022 |
Direct observation of a condensate effect on super-enhancer controlled gene bursting M Du, SH Stitzinger, JH Spille, WK Cho, C Lee, M Hijaz, A Quintana, ... Cell 187 (2), 331-344. e17, 2024 | 39 | 2024 |
qSR: a quantitative super-resolution analysis tool reveals the cell-cycle dependent organization of RNA Polymerase I in live human cells JO Andrews, W Conway, WK Cho, A Narayanan, JH Spille, N Jayanth, ... Scientific reports 8 (1), 7424, 2018 | 38 | 2018 |
A CRISPR/Cas9 platform for MS2-labelling of single mRNA in live stem cells JH Spille, M Hecht, V Grube, W Cho, C Lee, II Cissé Methods 153, 35-45, 2019 | 27 | 2019 |
Global analysis of double-strand break processing reveals in vivo properties of the helicase-nuclease complex AddAB A Badrinarayanan, TBK Le, JH Spille, II Cisse, MT Laub PLoS Genetics 13 (5), e1006783, 2017 | 19 | 2017 |
A first order phase transition underlies the formation of sub-diffractive protein aggregates in mammalian cells A Narayanan, AB Meriin, MY Sherman, II Cissé BioRxiv, 148395, 2017 | 10 | 2017 |