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Matthew Eaton
Matthew Eaton
Senior Scientist @ Syros Pharmaceuticals
Adresse e-mail validée de mit.edu - Page d'accueil
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An integrated encyclopedia of DNA elements in the human genome.
BE Bernstein, E Birney, I Dunham, ED Green, C Gunter, M Snyder
Nature 489 (7414), 57, 2012
13829*2012
Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
59522015
Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE
modENCODE Consortium, S Roy, J Ernst, PV Kharchenko, P Kheradpour, ...
Science 330 (6012), 1787-1797, 2010
10722010
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
PL De Jager, G Srivastava, K Lunnon, J Burgess, LC Schalkwyk, L Yu, ...
Nature neuroscience 17 (9), 1156-1163, 2014
9012014
A cis-regulatory map of the Drosophila genome
N Nègre, CD Brown, L Ma, CA Bristow, SW Miller, U Wagner, ...
Nature 471 (7339), 527-531, 2011
5672011
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ...
PLoS genetics 6 (2), e1000841, 2010
4582010
BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair
E Hatchi, K Skourti-Stathaki, S Ventz, L Pinello, A Yen, ...
Molecular cell 57 (4), 636-647, 2015
4482015
Conserved nucleosome positioning defines replication origins
ML Eaton, K Galani, S Kang, SP Bell, DM MacAlpine
Genes & development 24 (8), 748-753, 2010
4272010
Chromatin signatures of the Drosophila replication program
ML Eaton, JA Prinz, HK MacAlpine, G Tretyakov, PV Kharchenko, ...
Genome research 21 (2), 164-174, 2011
2052011
WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration.
MDDP Dwyer MA, Joseph JD, Wade HE, Eaton ML, Kunder RS
Cancer Research 70 (22), 9298-9308, 2010
1632010
Superenhancer analysis defines novel epigenomic subtypes of non-APL AML, including an RARα dependency targetable by SY-1425, a potent and selective RARα agonist
MR McKeown, MR Corces, ML Eaton, C Fiore, E Lee, JT Lopez, ...
Cancer discovery 7 (10), 1136-1153, 2017
1322017
Developmental control of gene copy number by repression of replication initiation and fork progression
N Sher, GW Bell, S Li, J Nordman, T Eng, ML Eaton, DM MacAlpine, ...
Genome research 22 (1), 64-75, 2012
1102012
The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin
P Müller, S Park, E Shor, DJ Huebert, CL Warren, AZ Ansari, M Weinreich, ...
Genes & development 24 (13), 1418-1433, 2010
972010
DNA copy number evolution in Drosophila cell lines
H Lee, CJ McManus, DY Cho, M Eaton, F Renda, MP Somma, L Cherbas, ...
Genome biology 15, 1-20, 2014
942014
Alzheimer's loci: epigenetic associations and interaction with genetic factors
LB Chibnik, L Yu, ML Eaton, G Srivastava, JA Schneider, M Kellis, ...
Annals of clinical and translational neurology 2 (6), 636-647, 2015
592015
Noncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant Cells
J Feng, H Gan, ML Eaton, H Zhou, S Li, JA Belsky, DM MacAlpine, ...
Molecular and cellular biology 36 (13), 1856-1867, 2016
422016
Multimodal regulation of E2F1 gene expression by progestins
HE Wade, S Kobayashi, ML Eaton, MS Jansen, EK Lobenhofer, M Lupien, ...
Molecular and cellular biology 30 (8), 1866, 2010
332010
Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML
S de Botton, T Cluzeau, C Vigil, RJ Cook, P Rousselot, DA Rizzieri, ...
Blood advances 7 (9), 1858-1870, 2023
132023
ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells
AW Lambert, C Fiore, Y Chutake, ER Verhaar, PC Strasser, MW Chen, ...
Developmental cell 57 (24), 2714-2730. e8, 2022
112022
Challenging the spliceosome machine
M Weir, M Eaton, M Rice
Genome biology 7, 1-15, 2006
102006
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