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Titus Boggon
Titus Boggon
Yale University School of Medicine
Adresse e-mail validée de yale.edu
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Année
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
JG Paez, PA Janne, JC Lee, S Tracy, H Greulich, S Gabriel, P Herman, ...
Science 304 (5676), 1497-1500, 2004
119362004
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
S Kobayashi, TJ Boggon, T Dayaram, PA Jänne, O Kocher, M Meyerson, ...
New England Journal of Medicine 352 (8), 786-792, 2005
47612005
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ...
Cancer cell 7 (4), 387-397, 2005
38142005
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
M Krauthammer, Y Kong, BH Ha, P Evans, A Bacchiocchi, JP McCusker, ...
Nature genetics 44 (9), 1006-1014, 2012
13212012
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
Z Zhang, JC Lee, L Lin, V Olivas, V Au, T LaFramboise, M Abdel-Rahman, ...
Nature genetics 44 (8), 852-860, 2012
12752012
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity
CH Yun, TJ Boggon, Y Li, MS Woo, H Greulich, M Meyerson, MJ Eck
Cancer cell 11 (3), 217-227, 2007
12022007
Structure and regulation of Src family kinases
TJ Boggon, MJ Eck
Oncogene 23 (48), 7918-7927, 2004
9002004
C-cadherin ectodomain structure and implications for cell adhesion mechanisms
TJ Boggon, J Murray, S Chappuis-Flament, E Wong, BM Gumbiner, ...
Science 296 (5571), 1308-1313, 2002
8472002
Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth
T Hitosugi, S Kang, MG Vander Heiden, TW Chung, S Elf, K Lythgoe, ...
Science signaling 2 (97), ra73-ra73, 2009
8302009
BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations
DB Costa, B Halmos, A Kumar, ST Schumer, MS Huberman, TJ Boggon, ...
PLoS medicine 4 (10), e315, 2007
5802007
Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation
N Romberg, K Al Moussawi, C Nelson-Williams, AL Stiegler, E Loring, ...
Nature genetics 46 (10), 1135-1139, 2014
4952014
G-protein signaling through tubby proteins
S Santagata, TJ Boggon, CL Baird, CA Gomez, J Zhao, WS Shan, ...
Science 292 (5524), 2041-2050, 2001
4602001
The structure and clinical relevance of the EGF receptor in human cancer
A Kumar, ET Petri, B Halmos, TJ Boggon
Journal of clinical oncology: official journal of the American Society of …, 2008
4552008
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth
T Hitosugi, L Zhou, S Elf, J Fan, HB Kang, JH Seo, C Shan, Q Dai, ...
Cancer cell 22 (5), 585-600, 2012
4242012
Genomic landscape of cutaneous T cell lymphoma
J Choi, G Goh, T Walradt, BS Hong, CG Bunick, K Chen, RD Bjornson, ...
Nature genetics 47 (9), 1011-1019, 2015
4212015
Activating alleles of JAK3 in acute megakaryoblastic leukemia
DK Walters, T Mercher, TL Gu, T O'Hare, JW Tyner, M Loriaux, VL Goss, ...
Cancer cell 10 (1), 65-75, 2006
3622006
Activating alleles of JAK3 in acute megakaryoblastic leukemia
DK Walters, T Mercher, TL Gu, T O'Hare, JW Tyner, M Loriaux, VL Goss, ...
Cancer cell 10 (1), 65-75, 2006
3622006
Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism
T Hitosugi, J Fan, TW Chung, K Lythgoe, X Wang, J Xie, Q Ge, TL Gu, ...
Molecular cell 44 (6), 864-877, 2011
3382011
Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth
L Jin, D Li, GN Alesi, J Fan, HB Kang, Z Lu, TJ Boggon, P Jin, H Yi, ...
Cancer cell 27 (2), 257-270, 2015
3242015
Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma
S Zhao, M Choi, JD Overton, S Bellone, DM Roque, E Cocco, F Guzzo, ...
Proceedings of the National Academy of Sciences 110 (8), 2916-2921, 2013
3122013
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