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Flavia Chiuppesi
Flavia Chiuppesi
Discovery Project Leader Herpesviruses, GSK
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Viral vectors: a look back and ahead on gene transfer technology
L Vannucci, M Lai, F Chiuppesi, L Ceccherini-Nelli, M Pistello
New Microbiologica 36 (1), 1-22, 2013
4412013
Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex
F Wussow, F Chiuppesi, J Martinez, J Campo, E Johnson, C Flechsig, ...
PLoS pathogens 10 (11), e1004524, 2014
1472014
Vaccine-derived neutralizing antibodies to the human cytomegalovirus gH/gL pentamer potently block primary cytotrophoblast infection
F Chiuppesi, F Wussow, E Johnson, C Bian, M Zhuo, A Rajakumar, ...
Journal of virology 89 (23), 11884-11898, 2015
982015
Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission
KM Bialas, T Tanaka, D Tran, V Varner, E Cisneros De La Rosa, ...
Proceedings of the National Academy of Sciences 112 (44), 13645-13650, 2015
972015
Ferritin as a reporter gene for in vivo tracking of stem cells by 1.5-T cardiac MRI in a rat model of myocardial infarction
M Campan, V Lionetti, GD Aquaro, F Forini, M Matteucci, L Vannucci, ...
American Journal of Physiology-Heart and Circulatory Physiology 300 (6 …, 2011
952011
MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults
C La Rosa, J Longmate, J Martinez, Q Zhou, TI Kaltcheva, W Tsai, J Drake, ...
Blood, The Journal of the American Society of Hematology 129 (1), 114-125, 2017
912017
Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform
F Chiuppesi, MA Salazar, H Contreras, VH Nguyen, J Martinez, Y Park, ...
Nature communications 11 (1), 6121, 2020
882020
Modeling human cytomegalovirus-induced microcephaly in human iPSC-derived brain organoids
G Sun, F Chiuppesi, X Chen, C Wang, E Tian, J Nguyen, M Kha, D Trinh, ...
Cell Reports Medicine 1 (1), 2020
792020
Adaptive NK cell reconstitution is associated with better clinical outcomes
F Cichocki, E Taras, F Chiuppesi, JE Wagner, BR Blazar, C Brunstein, ...
JCI insight 4 (2), 2019
692019
Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys
CS Nelson, DV Cruz, D Tran, KM Bialas, L Stamper, H Wu, M Gilbert, ...
JCI insight 2 (13), 2017
672017
Feline tetherin is characterized by a short N-terminal region and is counteracted by the feline immunodeficiency virus envelope glycoprotein
M Celestino, A Calistri, C Del Vecchio, C Salata, F Chiuppesi, M Pistello, ...
Journal of virology 86 (12), 6688-6700, 2012
482012
A fifty-year odyssey: prospects for a cytomegalovirus vaccine in transplant and congenital infection
DJ Diamond, C La Rosa, F Chiuppesi, H Contreras, S Dadwal, F Wussow, ...
Expert review of vaccines 17 (10), 889-911, 2018
452018
Synthetic multiantigen MVA vaccine COH04S1 protects against SARS-CoV-2 in Syrian hamsters and non-human primates
F Chiuppesi, VH Nguyen, Y Park, H Contreras, V Karpinski, K Faircloth, ...
npj Vaccines 7 (1), 7, 2022
382022
A lentiviral vector-based, herpes simplex virus 1 (HSV-1) glycoprotein B vaccine affords cross-protection against HSV-1 and HSV-2 genital infections
F Chiuppesi, L Vannucci, A De Luca, M Lai, B Matteoli, G Freer, ...
Journal of virology 86 (12), 6563-6574, 2012
382012
Neutralization of human cytomegalovirus entry into fibroblasts and epithelial cells
F Wussow, F Chiuppesi, H Contreras, DJ Diamond
Vaccines 5 (4), 39, 2017
372017
Safety and immunogenicity of a synthetic multiantigen modified vaccinia virus Ankara-based COVID-19 vaccine (COH04S1): an open-label and randomised, phase 1 trial
F Chiuppesi, JA Zaia, PH Frankel, R Stan, J Drake, B Williams, AM Acosta, ...
The Lancet Microbe 3 (4), e252-e264, 2022
362022
Multiantigenic modified vaccinia virus ankara vaccine vectors to elicit potent humoral and cellular immune reponses against human cytomegalovirus in mice
F Chiuppesi, J Nguyen, S Park, H Contreras, M Kha, Z Meng, T Kaltcheva, ...
Journal of virology 92 (19), 10.1128/jvi. 01012-18, 2018
342018
The AGMA1 poly (amidoamine) inhibits the infectivity of herpes simplex virus in cell lines, in human cervicovaginal histocultures, and in vaginally infected mice
M Donalisio, P Quaranta, F Chiuppesi, M Pistello, V Cagno, R Cavalli, ...
Biomaterials 85, 40-53, 2016
322016
Streamlined design of a self-inactivating feline immunodeficiency virus vector for transducing ex vivodendritic cells and T lymphocytes
M Pistello, L Vannucci, A Ravani, F Bonci, F Chiuppesi, B Del Santo, ...
Genetic vaccines and therapy 5, 1-13, 2007
272007
Plasmablast response to primary rhesus cytomegalovirus (CMV) infection in a monkey model of congenital CMV transmission
Q Fan, CS Nelson, KM Bialas, F Chiuppesi, J Amos, TC Gurley, ...
Clinical and Vaccine Immunology 24 (5), e00510-16, 2017
162017
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