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Daniel R. Woldring
Daniel R. Woldring
Adresse e-mail validée de egr.msu.edu
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Année
A 45-amino-acid scaffold mined from the PDB for high-affinity ligand engineering
MA Kruziki, S Bhatnagar, DR Woldring, VT Duong, BJ Hackel
Chemistry & biology 22 (7), 946-956, 2015
692015
High-throughput ligand discovery reveals a sitewise gradient of diversity in broadly evolved hydrophilic fibronectin domains
DR Woldring, PV Holec, H Zhou, BJ Hackel
PLoS One 10 (9), e0138956, 2015
482015
A gradient of sitewise diversity promotes evolutionary fitness for binder discovery in a three-helix bundle protein scaffold
DR Woldring, PV Holec, LA Stern, Y Du, BJ Hackel
Biochemistry 56 (11), 1656-1671, 2017
402017
Titratable avidity reduction enhances affinity discrimination in mammalian cellular selections of yeast-displayed ligands
LA Stern, CM Csizmar, DR Woldring, CR Wagner, BJ Hackel
ACS combinatorial science 19 (5), 315-323, 2017
332017
64Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor
MA Kruziki, BA Case, JY Chan, EJ Zudock, DR Woldring, D Yee, ...
Molecular pharmaceutics 13 (11), 3747-3755, 2016
212016
ScaffoldSeq: Software for characterization of directed evolution populations
DR Woldring, PV Holec, BJ Hackel
Proteins: Structure, Function, and Bioinformatics 84 (7), 869-874, 2016
122016
DesigN and evaluation of engineered extracellular vesicle (EV)-based targeting for EGFR-overexpressing tumor cells using monobody display
H Komuro, S Aminova, K Lauro, D Woldring, M Harada
Bioengineering 9 (2), 56, 2022
112022
Proposed three-phenylalanine motif involved in magnetoreception signalling of an Actinopterygii protein expressed in mammalian cells
B Ricker, S Mitra, EA Castellanos, CJ Grady, D Woldring, G Pelled, ...
Open Biology 13 (11), 230019, 2023
82023
Protein fitness prediction is impacted by the interplay of language models, ensemble learning, and sampling methods
M Mardikoraem, D Woldring
Pharmaceutics 15 (5), 1337, 2023
82023
Generative models for protein sequence modeling: recent advances and future directions
M Mardikoraem, Z Wang, N Pascual, D Woldring
Briefings in Bioinformatics 24 (6), bbad358, 2023
52023
Machine Learning-Driven Protein Library Design: A Path Toward Smarter Libraries
M Mardikoraem, D Woldring
Yeast Surface Display, 87-104, 2022
32022
Phytochemical drug discovery for COVID-19 using high-resolution computational docking and machine learning assisted binder prediction
Z Wang, T Belecciu, J Eaves, M Reimers, MH Bachmann, D Woldring
Journal of Biomolecular Structure and Dynamics 41 (14), 6643-6663, 2023
22023
Topological deep learning based deep mutational scanning
J Chen, DR Woldring, F Huang, X Huang, GW Wei
Computers in Biology and Medicine 164, 107258, 2023
22023
Ancestral Sequence Reconstruction and Alternate Amino Acid States Guide Protein Library Design for Directed Evolution
J VanAntwerp, P Finneran, B Dolgikh, D Woldring
Yeast Surface Display, 75-86, 2022
22022
Site-wise Diversification of Combinatorial Libraries Using Insights from Structure-guided StabilityStabilities Calculations
B Dolgikh, D Woldring
Yeast Surface Display, 63-73, 2022
22022
AP-LASR: Automated Protein Libraries from Ancestral Sequence Reconstruction
J VanAntwerp, M Mardikoraem, N Pascual, D Woldring
bioRxiv, 2023.10. 09.561537, 2023
12023
Evaluation of High Affinity Scaffolds from High-Throughput Discovery and Targeting DR5 and TNFR1
TL Senkow, DR Woldring, M Kruziki, BJ Hackel, JN Sachs
Biophysical Journal 112 (3), 530a, 2017
12017
Machine Learning Based Protein Engineering
D Woldring, L Stern
2023 AIChE Annual Meeting, 2023
2023
Computational, Structure, Biophysical Protein Engineering
D Woldring, P Jain
2023 AIChE Annual Meeting, 2023
2023
Single-Cell B-Cell Sequencing to Generate Natively Paired scFab Yeast Surface Display Libraries
N Pascual, T Belecciu, S Schmidt, A Nakisa, X Huang, D Woldring
Genotype Phenotype Coupling: Methods and Protocols, 175-212, 2023
2023
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