High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections L Zhang, K Yan, Y Zhang, R Huang, J Bian, C Zheng, H Sun, Z Chen, ... Proceedings of the National Academy of Sciences 104 (11), 4606-4611, 2007 | 294 | 2007 |
Recent advances in engineering nonribosomal peptide assembly lines M Winn, JK Fyans, Y Zhuo, J Micklefield Natural product reports 33 (2), 317-347, 2016 | 274 | 2016 |
Medium optimization for the production of avermectin B1a by Streptomyces avermitilis 14-12A using response surface methodology H Gao, M Liu, J Liu, H Dai, X Zhou, X Liu, Y Zhuo, W Zhang, L Zhang Bioresource Technology 100 (17), 4012-4016, 2009 | 202 | 2009 |
Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis Y Zhuo, W Zhang, D Chen, H Gao, J Tao, M Liu, Z Gou, X Zhou, BC Ye, ... Proceedings of the National Academy of Sciences 107 (25), 11250-11254, 2010 | 112 | 2010 |
Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis J Qiu, Y Zhuo, D Zhu, X Zhou, L Zhang, L Bai, Z Deng Applied microbiology and biotechnology 92 (2), 337-345, 2011 | 92 | 2011 |
Systematics-guided bioprospecting for bioactive microbial natural products X Liu, K Bolla, EJ Ashforth, Y Zhuo, H Gao, P Huang, SA Stanley, ... Antonie van Leeuwenhoek 101 (1), 55-66, 2012 | 57 | 2012 |
An enzyme cascade for selective modification of tyrosine residues in structurally diverse peptides and proteins AW Struck, MR Bennett, SA Shepherd, BJC Law, Y Zhuo, LS Wong, ... Journal of the American Chemical Society 138 (9), 3038-3045, 2016 | 56 | 2016 |
Identification of avermectin-high-producing strains by high-throughput screening methods H Gao, M Liu, X Zhou, J Liu, Y Zhuo, Z Gou, B Xu, W Zhang, X Liu, A Luo, ... Applied microbiology and biotechnology 85 (4), 1219-1225, 2010 | 49 | 2010 |
Synthetic biology of avermectin for production improvement and structure diversification Y Zhuo, T Zhang, Q Wang, P Cruz‐Morales, B Zhang, M Liu, ... Biotechnology journal 9 (3), 316-325, 2014 | 45 | 2014 |
Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites H Gao, Y Zhuo, E Ashforth, L Zhang Protein & cell 1 (7), 621-626, 2010 | 41 | 2010 |
Engineering of a genome-reduced host: practical application of synthetic biology in the overproduction of desired secondary metabolites H Gao, Y Zhuo, E Ashforth, L Zhang Protein & cell 1 (7), 621-626, 2010 | 41 | 2010 |
ContigScape: a Cytoscape plugin facilitating microbial genome gap closing B Tang, Q Wang, M Yang, F Xie, Y Zhu, Y Zhuo, S Wang, H Gao, X Ding, ... BMC genomics 14 (1), 289, 2013 | 40 | 2013 |
ABC transporters coupled with the elevated ergosterol contents contribute to the azole resistance and amphotericin B susceptibility B Ren, HQ Dai, G Pei, YJ Tong, Y Zhuo, N Yang, MY Su, P Huang, ... Applied microbiology and biotechnology 98 (6), 2609-2616, 2014 | 36 | 2014 |
Cloning and characterization of the gene cluster required for beauvericin biosynthesis in Fusarium proliferatum T Zhang, Y Zhuo, XP Jia, JT Liu, H Gao, FH Song, M Liu, LX Zhang Science China Life Sciences 56 (7), 628-637, 2013 | 32 | 2013 |
Magnetic field is the dominant factor to induce the response of Streptomyces avermitilis in altered gravity simulated by diamagnetic levitation M Liu, H Gao, P Shang, X Zhou, E Ashforth, Y Zhuo, D Chen, B Ren, Z Liu, ... PLoS One 6 (10), e24697, 2011 | 32 | 2011 |
Gene editing enables rapid engineering of complex antibiotic assembly lines WL Thong, Y Zhang, Y Zhuo, KJ Robins, JK Fyans, AJ Herbert, BJC Law, ... Nature communications 12 (1), 1-10, 2021 | 30 | 2021 |
3DScapeCS: application of three dimensional, parallel, dynamic network visualization in Cytoscape Q Wang, B Tang, L Song, B Ren, Q Liang, F Xie, Y Zhuo, X Liu, L Zhang BMC bioinformatics 14 (1), 322, 2013 | 21 | 2013 |
Cloning and characterization of a novel 2-ketoisovalerate reductase from the beauvericin producer Fusarium proliferatum LF061 T Zhang, XP Jia, Y Zhuo, M Liu, H Gao, JT Liu, L Zhang BMC biotechnology 12 (1), 55, 2012 | 18 | 2012 |
Assessing the potential of an induced-mutation strategy for avermectin overproducers H Gao, M Liu, Y Zhuo, X Zhou, J Liu, D Chen, W Zhang, Z Gou, P Shang, ... Applied and environmental microbiology 76 (13), 4583-4586, 2010 | 18 | 2010 |
A vitamin K-dependent carboxylase orthologue is involved in antibiotic biosynthesis BJC Law, Y Zhuo, M Winn, D Francis, Y Zhang, M Samborskyy, A Murphy, ... Nature Catalysis, 1, 2018 | 15 | 2018 |